EAAT2
EAAT2(兴奋性氨基酸转运蛋白2)
Excitatory amino acid transporter 2 (EAAT2) is the major glutamate transporter and functions to remove glutamate from synapses. An increase in EAAT2 protein expression and function may provide a means to prevent insufficient glutamate reuptake and consequently reduce neuronal damage.
The glial glutamate transporter EAAT2 plays a major role in glutamate clearance. EAAT2 can be upregulated by transcriptional or translational activation.EAAT2 is a potential target for the prevention of excitotoxicity.
EAAT2 相关产品(5)
- GC38524WAY-213613 hydrochlorideCAS: 2450268-84-3纯度: >98.50%
WAY-213613 is a potent, selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 with IC50 of 85 nM for excitatory amino acid transporter subtype 2 (EAAT2).
- GC64288EAAT2 activator 1CAS: 892415-28-0纯度: >98.00%
EAAT2 activator 1 是兴奋性氨基酸转运蛋白 2 (EAAT2) 的有效激活剂。EAAT2 是主要的谷氨酸转运蛋白，具有从突触中去除谷氨酸的功能。EAAT2 activator 1 以剂量依赖性方式增加 EAAT2 蛋白水平。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC10875 | LDN 212320 | 894002-50-7 | >98.00% | |
An activator of EAAT2 | ||||
| GC13659 | WAY 213613 | 868359-05-1 | >99.00% | |
WAY 213613 是一种有效的选择性人 EAAT2 抑制剂。 | ||||
| GC31075 | GT 949 | 460330-27-2 | >99.50% | |
A positive allosteric modulator of EEAT2 | ||||
| GC38524 | WAY-213613 hydrochloride | 2450268-84-3 | >98.50% | |
WAY-213613 is a potent, selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 with IC50 of 85 nM for excitatory amino acid transporter subtype 2 (EAAT2). | ||||
| GC64288 | EAAT2 activator 1 | 892415-28-0 | >98.00% | |
EAAT2 activator 1 是兴奋性氨基酸转运蛋白 2 (EAAT2) 的有效激活剂。EAAT2 是主要的谷氨酸转运蛋白，具有从突触中去除谷氨酸的功能。EAAT2 activator 1 以剂量依赖性方式增加 EAAT2 蛋白水平。 | ||||