GlpBio

Membrane Transporter/Ion Channel

Membrane Transporter/Ion Channel(跨膜转运)

研究方向

Membrane Transporter/Ion Channel 相关产品(2265)

  • GC34049 structure
    GC34049Aranidipine (MPC1304)
    CAS: 86780-90-7
    纯度: >99.00%

    Aranidipine (MPC1304) (MPC1304) 是一种 Ca2+ 通道拮抗剂，具有强效和持久的抗高血压作用。

  • GC34064 structure
    GC34064Aminooxyacetic acid hemihydrochloride (Carboxymethoxylamine Hemihydrochloride)
    CAS: 2921-14-4
    纯度: >98.00%

    Aminooxyacetic acid hemihydrochloride (Carboxymethoxylamine Hemihydrochloride)是一种苹果酸-天冬氨酸穿梭（MAS）抑制剂和γ-氨基丁酸转氨酶（GABA-T）抑制剂。

  • GC34079 structure
    GC34079Monepantel (AAD1566)
    CAS: 887148-69-8
    纯度: >99.50%

    Monepantel (AAD1566)是一种氨基乙腈衍生物类驱虫药，Monepantel可抑制mTOR/p70S6K信号通路诱导自噬。

  • GC34352 structure
    GC34352NMDAR antagonist 1
    CAS: 2220162-06-9

    NMDAR antagonist 1 is a potent and orally bioavailable NR2B-selective antagonist of NMDAR. It has neuroprotective activity.

  • GC34362 structure
    GC34362SSD114 hydrochloride
    CAS: 2319790-02-6
    纯度: >99.00%

    SSD114hydrochloride是一种新型GABAB受体正变构调节剂。

  • GC34486 structure
    GC34486BI 01383298
    CAS: 2227549-00-8
    纯度: >99.50%

    An NaCT inhibitor

  • GC34489 structure
    GC34489BI-749327
    CAS: 2361241-23-6
    纯度: >98.00%

    BI-749327是一种可口服利用的TRPC6拮抗剂，

  • GC34492 structure
    GC34492BI-9627
    CAS: 1204329-34-9
    纯度: >98.50%

    An NHE1 inhibitor

  • GC34494 structure
    GC34494Bifenazate
    CAS: 149877-41-8
    纯度: >99.50%

    An acaricide

  • GC34532 structure
    GC34532CFTR corrector 2
    CAS: 1628416-28-3
    纯度: >99.50%

    FDL169 is a CFTR corrector that is designed to fix and restore the function of the defective CFTR protein.

  • GC34574 structure
    GC34574Endovion
    CAS: 265646-85-3
    纯度: >99.00%

    Endovion (NS 3728, SCO-101) is a potent anion channel inhibitor that blocks the Volume Regulated Anion Channels (VRAC).

  • GC34616 structure
    GC34616HMR 1556
    CAS: 223749-46-0
    纯度: >99.50%

    HMR1556，色氨醇衍生物，是一种IKs阻滞剂，在犬和豚鼠的左心室肌细胞中的IC50值分别为10.5nM、34nM。

  • GC34638 structure
    GC34638JNJ-61432059
    CAS: 2035814-50-5
    纯度: >99.00%

    JNJ-61432059是具有口服活性的、选择性的AMPAR的负向调节剂，其对GluA1/γ-8的pIC50值为9.7。在老鼠的海马体中显示出具有时间和剂量依赖性的AMPA受体占用情况，在角膜点燃癫痫动物模型中显示出较强的保护作用。

  • GC34665 structure
    GC34665Metaflumizone
    CAS: 139968-49-3

    Metaflumizone是一种缩氨基脲杀虫剂，为有效的钠离子通道(sodiumchannel)阻滞剂。

  • GC34745 structure
    GC34745PTI-428
    CAS: 1953130-87-4
    纯度: >99.50%

    PTI-428是一种可增强并稳定囊性纤维化跨膜传导调节因子（CFTR）蛋白功能的特异性调节剂。

  • GC34753 structure
    GC34753Radiprodil
    CAS: 496054-87-6
    纯度: >99.00%

    An NMDA receptor antagonist

  • GC34828 structure
    GC34828Tat-NR2B9c TFA
    CAS: 1834571-04-8
    纯度: >99.50%

    Tat-NR2B9c(TFA)是由20个氨基酸组成的多肽，为PSD-95的抑制剂，对PSD-95d2和PSD-95d1的EC50值分别为6.7nM和670nM。Tat-NR2B9c同时可降低NMDA诱导的p38的活化，具有神经保护作用。

  • GC34833 structure
    GC34833TC-I 2014
    CAS: 1221349-53-6
    纯度: >99.00%

    TC-I2014(compound5)是一种强效的、苯并咪唑类的、TRPM8的拮抗剂，其对犬类、人和大鼠通道的IC50值分别为0.8nM,3.0nM和4.4nM。在疼痛动物模型中具有抗痛觉超敏作用。

  • GC34912 structure
    GC34912Levamlodipine besylate
    CAS: 150566-71-5
    纯度: >99.50%

    Levamlodipine Besylate is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina.

  • GC34951 structure
    GC34951(-)-Menthol
    CAS: 2216-51-5
    纯度: >98.00%

    A monoterpene with diverse biological activities

  • GC34952 structure
    GC34952(-)-Sparteine sulfate pentahydrate
    CAS: 6160-12-9
    纯度: >98.00%

    Sparteine Sulfate, a quinolizidine alkaloid, is the sulfate form of sparteini, which is a sodium channel blocker used as an oxytocic and an anti-arrhythmia agent.

  • GC34954 structure
    GC34954(+)-Borneol
    CAS: 464-43-7
    纯度: >98.00%

    A bicyclic monoterpene with diverse biological activities

  • GC34959 structure
    GC34959(+)-Sparteine
    CAS: 492-08-0
    纯度: >98.60%

    A quinolizidine alkaloid

  • GC34986 structure
    GC34986(R)-Baclofen hydrochloride
    CAS: 63701-55-3
    纯度: >98.00%

    A GABA B receptor agonist