GlpBio

BI 01383298

目录号: GC34486纯度: >99.50%
An NaCT inhibitor
BI 01383298
Cas No.: 2227549-00-8
规格价格库存数量操作
1mg¥140.00现货
1
5mg¥325.00现货
1
10mg¥571.00现货
1
25mg¥1,164.00现货
1
50mg¥1,715.00现货
1
100mg¥2,529.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    641, 529–536 (2025)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

BI-01383298 is an inhibitor of the sodium-coupled citrate transporter (NaCT; IC50 = ~100 nM).1 It irreversibly inhibits sodium-dependent citrate uptake, but not nicotinate, arginine, glutamine, tryptophan, or lactate uptake, in HepG2 cells when used at concentrations ranging from 0.01 to 1 ?M.

1.Higuchi, K., Kopel, J.J., Sivaprakasam, S., et al.Functional analysis of a species-specific inhibitor selective for human Na+-coupled citrate transporter (NaCT/SLC13A5/mINDY)Biochem. J.477(21)4149-4165(2020)

产品文档 Product Documents

Purity:>99.50%

化学性质Chemical Properties

CAS 号
2227549-00-8
SMILES
O=C(C1CCN(S(=O)(C2=CC(Cl)=CC(Cl)=C2)=O)CC1)NCC3=CC=C(F)C=C3
分子式
C19H19Cl2FN2O3S
分子量
445.34 g/mol
溶解性
DMSO : 37.5 mg/mL (84.21 mM);Water : < 0.1 mg/mL (insoluble)
保存条件
Store at -20°C,protect from light
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol