GlpBio

Membrane Transporter/Ion Channel

Membrane Transporter/Ion Channel(跨膜转运)

研究方向

Membrane Transporter/Ion Channel 相关产品(2265)

  • GC30917 structure
    GC30917AM-2099
    CAS: 1443373-17-8
    纯度: >98.00%

    AM-2099是电压门控钠通道Nav1.7的有效，选择性的抑制剂，对人类Nav1.7的IC50值为0.16μM。

  • GC30927 structure
    GC30927Acevaltrate
    CAS: 25161-41-5
    纯度: >98.00%

    Acevaltrate, an active component derived from the herbal plant Valeriana jatamansi Jones, is strikingly potent to induce GBM cell apoptosis. Acevaltrate inhibits the Na+/K+-ATPase activity in the rat kidney and brain hemispheres with IC50 of 22.8 μM and 42.3 μM, respectively.

  • GC30930 structure
    GC30930DAA-1106
    CAS: 220551-92-8
    纯度: >99.50%

    A TSPO agonist

  • GC30933 structure
    GC30933(+)-Kavain
    CAS: 500-64-1
    纯度: >98.00%

    A kavalactone with diverse biological activities

  • GC30943 structure
    GC309436,2'-Dihydroxyflavone
    CAS: 92439-20-8
    纯度: >99.50% / >98.00%

    6,2'-Dihydroxyflavone是一个新型的GABAA受体拮抗剂。

  • GC30946 structure
    GC30946Procyclidine hydrochloride ((±)-Procyclidine hydrochlorid)
    CAS: 1508-76-5
    纯度: >99.00%

    A muscarinic acetylcholine receptor antagonist

  • GC30950 structure
    GC30950TTA-Q6
    CAS: 910484-28-5
    纯度: >99.50%

    TTA-Q6是T型Ca2+通道的选择性拮抗剂，可用于神经学研究。

  • GC30951 structure
    GC30951MDL 105519
    CAS: 161230-88-2

    MDL105519是有效和选择性的甘氨酸与NMDA受体结合的拮抗剂。

  • GC30957 structure
    GC30957Propoxycaine hydrochloride
    CAS: 550-83-4
    纯度: >99.50%

    Propoxycaine盐酸盐是一种局部麻醉剂,结合并抑制电压门控钠通道,抑制脉冲起始和传导所需的离子通量,从而导致感觉的丢失。

  • GC30961 structure
    GC30961Mirogabalin besylate (DS 5565 besylate)
    CAS: 1138245-21-2
    纯度: >99.00%

    A calcium channel blocker

  • GC30973 structure
    GC30973Mephenesin
    CAS: 59-47-2
    纯度: >98.00%

    Mephenesin (Decontractyl, Cresoxydiol, Memphenesin, Mephedan) is centrally acting muscle relaxant, a topical analgesic and may be an NMDA receptor antagonist.

  • GC30977 structure
    GC30977Ca2+ channel agonist 1
    CAS: 1402821-24-2
    纯度: >99.50%

    Ca2+channelagonist1是一种N-型钙离子通道(N-typeCa2+channel)激动剂和Cdk2的抑制剂，EC50分别为14.23μM和3.34μM，对运动神经终端功能障碍有潜在疗效。

  • GC30983 structure
    GC30983alpha-Asarone (α-Asarone)
    CAS: 2883-98-9
    纯度: >99.50%

    An inhibitor of HMG- CoA reductase and CYP450 isoforms

  • GC30984 structure
    GC30984XEN907
    CAS: 912656-34-9
    纯度: >99.50%

    XEN907是一种新型的螺羟吲哚类NaV1.7阻断剂,抑制hNaV1.7,IC50为3nM。

  • GC30986 structure
    GC30986Nicardipine (YC-93)
    CAS: 55985-32-5
    纯度: >99.50%

    Nicardipine is a potent calcium channel blockader with marked vasodilator action.

  • GC30994 structure
    GC30994Vanilpyruvic acid (Vanylpyruvic acid)
    CAS: 1081-71-6
    纯度: >98.00%

    香草丙酮酸 (Vanylpyruvic acid) 是儿茶酚胺代谢物和香草乳酸的前体。

  • GC30997 structure
    GC30997NS-638
    CAS: 150493-34-8
    纯度: >98.00%

    An N- and L-type calcium channel inhibitor

  • GC31002 structure
    GC31002Nav1.7-IN-2
    CAS: 1332295-35-8
    纯度: >99.50%

    Nav1.7-IN-2是电压门控钠通道抑制剂,尤其是Nav1.7,IC50值为80nM。

  • GC31010 structure
    GC31010AZD-6280
    CAS: 942436-93-3
    纯度: >99.00%

    AZD-6280 is a selective GABAA (α2/3) receptor modulator, used for treatment of generalized anxiety disorder.

  • GC31013 structure
    GC31013U-101017 (PNU 101017)
    CAS: 170568-47-5

    U-101017 (PNU 101017) 是苯二氮卓受体和 GABAA 受体的部分激动剂，具有抗焦虑作用。

  • GC31018 structure
    GC31018NEO 376 (SPI-376)
    CAS: 496921-73-4

    NEO 376 (SPI-376) 是 5-HT1 受体、GABA 受体和多巴胺受体的选择性调节剂，具有抗精神病活性。

  • GC31019 structure
    GC31019GV-196771A
    CAS: 166974-23-8

    GV-196771A是GV196771的钠盐形式。是NMDA受体拮抗剂。

  • GC31023 structure
    GC31023Ethyl dirazepate
    CAS: 23980-14-5

    Ethyldirazepate是一种苯并二氮杂(benzodiazepine)衍生物。具有抗焦虑和催眠特性。

  • GC31036 structure
    GC31036MRZ 2-514
    CAS: 202808-11-5

    MRZ2-514是一种NMDAreceptor(glycineB)的拮抗剂，Ki值为33μM。