GlpBio

Membrane Transporter/Ion Channel

Membrane Transporter/Ion Channel(跨膜转运)

研究方向

Membrane Transporter/Ion Channel 相关产品(2265)

  • GC30807 structure
    GC30807ZSET1446 (ST-101)
    CAS: 887603-94-3
    纯度: >98.00%

    ZSET1446 (ST-101) 是一种新型认知增强剂，可显着改善各种类型的阿尔茨海默病 (AD) 模型中的学习缺陷。

  • GC30813 structure
    GC30813Raxatrigine hydrochloride (GSK-1014802 hydrochloride)
    CAS: 934240-31-0
    纯度: >99.00%

    An inhibitor of voltage-gated sodium channels

  • GC30815 structure
    GC30815Synaptamide (Dehydroepiandrosteron(DHEA))
    CAS: 162758-94-3
    纯度: >98.00%

    Synaptamide (Dehydroepiandrosteron(DHEA))是一种内源性GPR110（ADGRF1）配体，可刺激cAMP生成，EC 50 值为1.27nM。

  • GC30818 structure
    GC30818ZL006
    CAS: 1181226-02-7
    纯度: >98.00%

    An nNOS/PSD-95 interaction inhibitor

  • GC30827 structure
    GC30827Pipequaline (PK-8165)
    CAS: 77472-98-1
    纯度: >99.50%

    A partial agonist of central benzodiazepine receptors

  • GC30835 structure
    GC30835Rislenemdaz (MK-0657)
    CAS: 808732-98-1
    纯度: >99.50%

    Rislenemdaz (MK-0657) (CERC-301) 是一种口服生物可利用的选择性 N-甲基-D-天冬氨酸 (NMDA) 受体亚基 2B (GluN2B) 拮抗剂，其 Ki 和 IC 50 分别为 8.1 nM 和 3.6 nM。

  • GC30837 structure
    GC30837A-1165442
    CAS: 1221443-94-2
    纯度: >99.50%

    A-1165442是有效，竞争性，有口服活性的TRPV1拮抗剂，对人TRPV1的IC50值为9nM。

  • GC30839 structure
    GC30839Traxoprodil
    CAS: 134234-12-1
    纯度: >99.00%

    An antagonist of NR2B subunit-containing NMDA receptors

  • GC30844 structure
    GC30844Afloqualone
    CAS: 56287-74-2
    纯度: >98.00%

    An Analytical Reference Standard

  • GC30847 structure
    GC30847IC87201
    CAS: 866927-10-8

    An inhibitor of the nNOS-PSD-95 protein-protein interaction

  • GC30850 structure
    GC30850GV-58
    CAS: 1402821-41-3
    纯度: >99.50%

    GV-58 is a novel, selective N-type and P/Q-type Ca2+ channels agonist with IC50s of 7.21 μM and 8.81 μM, respectively.

  • GC30852 structure
    GC30852Org-26576
    CAS: 1026791-61-6
    纯度: >99.50%

    Org26576是AMPA受体的正变构调节剂。

  • GC30860 structure
    GC30860Neu2000
    CAS: 640290-67-1
    纯度: >98.50%

    Neu2000 (Salfaprodil free base) 是 N-甲基-D-天冬氨酸 (NMDA) 的 NR2B 选择性和非竞争性拮抗剂。

  • GC30862 structure
    GC30862L-Cycloserine ((S)-4-Amino-3-isoxazolidone)
    CAS: 339-72-0
    纯度: >99.00%

    An inhibitor of sphingolipid synthesis and aminotransferases

  • GC30865 structure
    GC30865TPA 023
    CAS: 252977-51-8
    纯度: >99.50%

    TPA023是GABAAα2/α3的选择性的激动剂，Ki值为0.19-0.41nM。

  • GC30866 structure
    GC30866Anabasine ((S)-Anabasine)
    CAS: 494-52-0
    纯度: >99.00%

    Anabasine ((S)-Anabasine) ((S)-Anabasine ((S)-Anabasine)) 是一种生物碱，在烟草 (Nicotiana) 中是一种微量成分。

  • GC30873 structure
    GC30873Mirogabalin (DS5565)
    CAS: 1138245-13-2
    纯度: >99.00%

    A calcium channel blocker

  • GC30889 structure
    GC30889(-)-Securinine
    CAS: 5610-40-2
    纯度: >98.00%

    An alkaloid

  • GC30891 structure
    GC30891Almitrine mesylate (Almitrine bismesylate)
    CAS: 29608-49-9
    纯度: >98.00%

    Almitrine mesylate (Almitrine bismesylate, Almitrine dimethanesulfonate, Almitrine dimesylate), a pharmacologically unique respiratory stimulant, acts as an agonist of peripheral chemoreceptors located on the carotid bodies. Almitrine mesylate inhibits the activity of Ca2+-dependent K+ channel by decreasing its open probability with IC50 of 0.22 μM.

  • GC30893 structure
    GC30893TRPM8 Antagonist
    CAS: 259674-19-6
    纯度: >98.00%

    TRPM8 antagonist 2 (TRPM8 Antagonist) is a potent and selective antagonist of TRPM8 with IC50 of 0.2 nM that can be used for the pharmacological treatment of neuropathic pain syndromes.

  • GC30898 structure
    GC308986-Methylflavone
    CAS: 29976-75-8
    纯度: >98.00%

    6-methylflavone是α1β2γ2L和α1β2GABAA受体的激活剂。

  • GC30910 structure
    GC30910Eucalyptol (1,8-Cineole)
    CAS: 470-82-6

    Eucalyptol是5-HT3受体,钾通道,TNF-α和IL-1β的抑制剂。

  • GC30911 structure
    GC30911Apimostinel (NRX-1074)
    CAS: 1421866-48-9
    纯度: >99.00%

    Apimostinel (NRX-1074) (NRX-1074; AGN-241660) 是一种具有口服活性的 NMDA 受体部分激动剂。

  • GC30914 structure
    GC30914Butamben (Butyl 4-aminobenzoate)
    CAS: 94-25-7
    纯度: >98.00%

    Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.