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Home >> Signaling Pathways >> Membrane Transporter/Ion Channel

Membrane Transporter/Ion Channel(跨膜转运)

  1. Cat.No. 产品名称 Information
  2. GC49820 10,11-dihydro-10,11-dihydroxy Carbamazepine

    奥卡西平杂质

     A metabolite of carbamazepine and oxcarbazepine
  3. GC13863 10Panx

    10Panx

     A peptide inhibitor of PANX1
  4. GC46047 14-Anhydrodigitoxigenin A cardenolide
  5. GC40453 16(R)-HETE

    16(R)-Hydroxyeicosatetraenoic Acid

     A potent vasodilator
  6. GC40454 16(S)-HETE

    16(S)-Hydroxyeicosatetraenoic Acid

     A potent inhibitor of proximal tubule ATPase activity
  7. GC40455 17(R)-HETE

    17(R)-Hydroxyeicosatetraenoic Acid

     An inactive isomer of 17-HETE
  8. GC40456 17(S)-HETE

    17(S)-Hydroxyeicosatetraenoic Acid

     A potent inhibitor of proximal tubule ATPase activity
  9. GC17223 17-PA 17-PA 是神经类固醇增强和 GABAA 受体直接门控的选择性拮抗剂。
  10. GC46464 17R(18S)-EpETE

    17R,18S-EEQ, 17R,18S-epoxy Eicosatetraenoic Acid

     An EPA metabolite and activator of KCa1.1/BK channels
  11. GC90815 2',3'-cyclic NADP+ (sodium salt)

    2′,3′-cNADP+, β-Nicotinamide adenine dinucleotide-2',3'-cyclic phosphate

    一种CNP的底物。
  12. GC90813 2'-deoxy NAD+ (sodium salt)

    2'-deoxy Nicotinamide adenine dinucleotide

    TRPM2激动剂
  13. GC70652 2'MeO6MF 2'MeO6MF是α2β1γ2L和所有含α1的GABAA受体的脑渗透阳性变构调节剂。
  14. GC60017 2'-O-Methylisoliquiritigenin

    4,4'-二羟基-2'-甲氧基查耳酮

     2'-O-Methylisoliquiritigenin可从Arachis中分离得到，可上调5-HT、NE、DA和GABA信号通路，对NE通路影响不大。
  15. GC60455 2,2,2-Trichloroethanol

    2,2,2-三氯乙醇

     2,2,2-Trichloroethanol是镇静催眠药水合氯醛的活性形式，是非经典的K2P通道TREK-1和TRAAK的激动剂。
  16. GC12469 2,3-Butanedione-2-monoxime

    2,3-丁烷二酮一肟,BDM|Diacetyl Monoxime|NSC 660|NSC 116103

     A non-selective myosin ATPase inhibitor
  17. GC17562 2-APB

    二苯基硼酸-2-氨基乙酯,2-APB

     2-APB是一种钙离子通道的非特异性拮抗剂，通常被用于研究钙信号传导，如细胞凋亡、肌肉收缩和神经传导等方面。
  18. GC49718 2-Chloroadenosine 5-triphosphate (sodium salt)

    2-chloro ATP

     An adenine nucleotide and ATP analog
  19. GC11267 2-Hydroxysaclofen

    3-氨基-2-4-氯苯基-2-羟基丙烷磺酸

     2-Hydroxysaclofen 是一种有效的 γ-amino-butyric-acid-B (GABAB) 受体拮抗剂。
  20. GC15416 2-Methylthioadenosine triphosphate tetrasodium salt 2-Methylthioadenosine triphosphate tetrasodium salt 是一种非特异性 P2 受体激动剂。
  21. GN10799 20(S)-Ginsenoside Rg3

    20(S)-人参皂苷 Rg3; 20(S)-Propanaxadiol; S-ginsenoside Rg3

     20(S)-Ginsenoside Rg3是从人参中提取的稀有人参皂苷（Na+：IC50 = 32.2±4.5μM；hKv1.4：IC50 = 32.6±2.2μM）。
  22. GC40377 20-HEPE An EPA metabolite
  23. GC35075 20-HETE

    20-羟基二十碳-5Z,8Z,11Z,14Z-四烯酸

    A cytochrome P450 (CYP450) metabolite of arachidonic acid
  24. GC33673 24-Hydroxycholesterol

    24-羟基胆固醇

    24-Hydroxycholesterol是一种天然的固醇类物质，是n-甲基-d-天门冬氨酸受体(NMDA)和转录因子LXR的激活剂。
  25. GC48395 3,3',5-Triiodo-L-thyronine (sodium salt hydrate)

    三碘代甲状腺素钠盐水合物; Triiodothyronine sodium hydrate; 3,3',5-Triiodo-L-thyronine sodium hydrate; T3 sodium hydrate

     A thyroid hormone
  26. GC33703 3,4,5-Trimethoxycinnamic acid

    3,4,5-三甲氧基肉桂酸

     3,4,5-Trimethoxycinnamic acid (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at the GABAA/BZ receptor complex.
  27. GC11757 3-Bromocytisine

    3-Br-cytisine

     3-Bromocytisine (3-Br-cytisine) 是一种有效的 nACh 受体激动剂，对 hα4β4、hα4β2 和 hα7-nACh 的 IC50 分别为 0.28、0.30 和 31.6 nM。
  28. GC35108 3-Deoxyaconitine

    3-脱氧乌头碱

     3-Deoxyaconitine is a diterpenoid alkaloid isolated from the root of Aconitum Carmichaeli Debx.
  29. GC12506 3-Methyl-GABA 3-Methyl-GABA 是一种有效的 GABA 氨基转移酶激活剂。
  30. GC91154 33-BCRP Inhibitor

    33-Breast Cancer Resistance Protein Inhibitor

    一种BCRP抑制剂
  31. GC70850 4′-Demethylnobiletin 4′-Demethylnobiletin是一种生物活性代谢产物，可激活PKA/ERK/CREB信号通路，并通过刺激ERK信号传导逆转与NMDA受体拮抗相关的记忆损伤。
  32. GC42475 4α-Phorbol 12,13-didecanoate

    4αPDD

     A TRPV4 activator
  33. GC49252 4’-hydroxy Trazodone A metabolite of trazodone
  34. GC17675 4,4-Pentamethylenepiperidine hydrochloride M2 proton channel blocker
  35. GC42327 4,9-Anhydrotetrodotoxin

    4,9-anhydro-TTX

     A selective blocker of Nav1.6 channels
  36. GC68080 4-(Phenyldiazenyl)benzoic acid 4-(Phenyldiazenyl)benzoic acid 是一种光敏和可控的 TRPA1 激动剂，可作为研究疼痛信号的药理学工具。
  37. GC91680 4-Acetamido Antipyrine

    4-AAAP,NSC 331807

     4-Acetamido antipyrine (4-AAAP) is an active metabolite of the non-opioid analgesic and antipyretic prodrug metamizole .
  38. GC33504 4-Acetamidobutanoic acid (N-acetyl GABA)

    4-乙酰氨基丁酸,N-acetyl GABA

     A GABA derivative
  39. GC17469 4-Aminopyridine

    4-AP, BRL 34915, Dalfampridine, Fampridine, NSC 15041

    potassium channel-blocking agent
  40. GC42346 4-bromo A23187

    4-溴代-钙离子载体,4-Bromocalcimycin

     A non-fluorescent calcium ionophore
  41. GC49575 4-hydroxy Omeprazole sulfide

    埃索美拉唑有关物质

     A metabolite of omeprazole
  42. GC42414 4-hydroxy Tolbutamide

    4-羟基甲苯磺丁脲,Hydroxytolbutamide

     4-Hydroxy Tolbutamide是第一代磺酰脲类降血糖药甲苯磺丁脲在人体内经CYP2C9代谢的主要产物。
  43. GA20418 4-Hydroxy-hippuric acid

    4-羟基马尿酸,p-Hydroxyhippuric Acid; para-Hydroxyhippuric Acid

     An OAT1 inhibitor
  44. GC60517 4-Hydroxyatomoxetine

    4'-羟基托莫西汀

     A metabolite of atomoxetine
  45. GC63628 4-Hydroxymidazolam

    4-羟基咪达唑仑

    4-Hydroxymidazolam 是 Midazolam 的一种主要代谢产物。Midazolam 是一种有效的苯二氮卓类药物，具有促进精神安定的活性。
  46. GC18631 4BP-TQS An agonist of α7 subunit-containing nAChRs
  47. GC16801 5'-Iodoresiniferatoxin TRPV1 (VR1) receptor antagonist
  48. GC48843 5α-Androst-16-en-3α-ol

    (3α,5α)-16-烯-3-甾醇

     A pheromone with diverse biological activities
  49. GC49326 5β-Dihydroprogesterone

    5Β-二氢孕酮

     A progesterone receptor agonist and metabolite of progesterone
  50. GC16799 5,7-Dichlorokynurenic acid

    5,7-二氯犬尿喹啉酸; 5,7-DCKA

     An NMDA receptor antagonist
  51. GC14598 5,7-Dichlorokynurenic acid sodium salt An NMDA receptor antagonist

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