Chromatin/Epigenetics
Chromatin/Epigenetics(染色质/表观遗传学)
Epigenetics
Epigenetics means above genetics. It determines how much and whether a gene is expressed without changing DNA sequences. Epigenetic regulations include, 1. DNA methylation: the addition of methyl group to DNA, converting cytosine to 5-methylcytosine, mostly at CpG sites; 2. Histone modifications: posttranslational modificationEpigeneticss of histone proteins including acetylation, methylation, ubiquitylation, phosphorylation and sumoylation; 3. miRNAs: non-coding microRNA downregulating gene expression; 4. Prions: infectious proteins viewed as epigenetic agents capable of inducing a phenotype without changing the genome.
- Bromodomain(50)
- Aurora Kinase(63)
- DNA Methyltransferase(35)
- HDAC(210)
- Histone Acetyltransferases(78)
- Histone Demethylases(110)
- Histone Methyltransferase(240)
- HIF(102)
- JAK(173)
- MBT Domains(1)
- PARP(122)
- Pim(32)
- Protein Ser/Thr Phosphatases(34)
- RNA Polymerase(7)
- Sirtuin(77)
- Sphingosine Kinase-2(1)
- Polycomb repressive complex(2)
- SUMOylation(3)
- PAD(21)
- Epigenetic Reader Domain(246)
- MicroRNA(24)
- Protein Arginine Deiminase(7)
- Chromodomain(1)
- Citrullination(20)
- DNA/RNA Demethylation(2)
- DNA/RNA Methylation(8)
- Histone Deacetylation(44)
- Histones/Histone Peptides(62)
- PHD Domains(1)
- Tandem Tudor & Tudor-like Domains(1)
- PRMT(2)
- Readers(1)
- Small Interfering RNA (siRNA)(1)
- METTL3(2)
- WDR5(1)
- TET Protein(2)
- HuR(1)
- SF3B1(1)
Chromatin/Epigenetics 相关产品(1617)
- GC41695(6R,S)-5,6,7,8-Tetrahydrofolic Acid (hydrochloride)CAS: 150731-85-4纯度: >95.00%
A folic acid derivative
- GC420752,4-Pyridinedicarboxylic Acid (hydrate)CAS: 207671-42-9纯度: >98.00%
An inhibitor of 2-oxoglutarate-dependent enzymes
- GC42785Amifostine (hydrate)CAS: 112901-68-5纯度: >98.00%
Amifostine (hydrate)是一种广谱的正常细胞保护剂，主要用于减轻化疗或放疗对正常组织的毒性。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC40555 | Tiopronin | 1953-02-2 | >98.00% | |
Tiopronin is an antioxidant that has diverse biological activities. | ||||
| GC40628 | TP-472 | 2079895-62-6 | >98.00% | |
A BRD9 inhibitor | ||||
| GC40667 | Aurora Kinase Inhibitor II | 331770-21-9 | >99.00% | |
Blocks Aurora A kinase activity | ||||
| GC40674 | APHA Compound 8 | 676599-90-9 | >98.00% | |
A class I and II HDAC inhibitor | ||||
| GC40767 | CAY10669 | 1243583-88-1 | >98.00% | |
An inhibitor of PCAF | ||||
| GC40791 | MS-1020 | 1255516-86-9 | >95.00% | |
A cell-permeable inhibitor of JAK3 | ||||
| GC40900 | Ganoderic Acid D | 108340-60-9 | >98.00% | |
An oxygenated triterpenoid | ||||
| GC40918 | Gramicidin A | 11029-61-1 | >90.00% | |
Gramicidin A是一种由B.brevis产生的线性五肽抗生素。 | ||||
| GC40923 | BRD4884 | 1404559-91-6 | >98.00% | |
A kinetically selective HDAC2 inhibitor | ||||
| GC41085 | HDAC6 Inhibitor | 1259296-46-2 | >99.00% | |
An inhibitor of HDAC6 | ||||
| GC41088 | (6S)-Tetrahydrofolic Acid | 71963-69-4 | >95.00% | |
An active diastereomer | ||||
| GC41263 | TP-064 | 2080306-20-1 | >98.00% | |
A potent inhibitor of PRMT4 | ||||
| GC41495 | HDAC3 Inhibitor | 2044701-99-5 | >98.00% | |
An allosteric HDAC3 inhibitor | ||||
| GC41572 | PRLX-93936 | 903499-49-0 | >98.00% | |
An erastin analog with antitumor activity | ||||
| GC41601 | CAY10591 | 839699-72-8 | >98.00% | |
A SIRT1 activator | ||||
| GC41625 | Oroxylin A | 480-11-5 | >98.00% | |
A flavonoid with diverse biological activities | ||||
| GC41638 | TSI-01 | 704878-75-1 | >95.00% / >98.00% | |
TSI-01是溶血磷脂酰胆碱酰基转移酶2（LPCAT2）的选择性抑制剂，对人 LPCAT2和LPCAT1的IC 50 值分别为0.47和3.02μM。 | ||||
| GC41695 | (6R,S)-5,6,7,8-Tetrahydrofolic Acid (hydrochloride) | 150731-85-4 | >95.00% | |
A folic acid derivative | ||||
| GC41984 | 1-Alaninechlamydocin | 141446-96-0 | >95.00% | |
An HDAC inhibitor | ||||
| GC42075 | 2,4-Pyridinedicarboxylic Acid (hydrate) | 207671-42-9 | >98.00% | |
An inhibitor of 2-oxoglutarate-dependent enzymes | ||||
| GC42466 | 4-pentynoyl-Coenzyme A (trifluoroacetate salt) | - | >95.00% | |
A protein acetylation probe | ||||
| GC42562 | 5-Methyl-2'-deoxycytidine | 838-07-3 | >98.00% | |
A pyrimidine nucleoside | ||||
| GC42784 | AMI-1 (sodium salt) | - | >99.00% | |
A cell permeable inhibitor of PRMTs | ||||
| GC42785 | Amifostine (hydrate) | 112901-68-5 | >98.00% | |
Amifostine (hydrate)是一种广谱的正常细胞保护剂，主要用于减轻化疗或放疗对正常组织的毒性。 | ||||