Chromatin/Epigenetics
Chromatin/Epigenetics(染色质/表观遗传学)
Epigenetics
Epigenetics means above genetics. It determines how much and whether a gene is expressed without changing DNA sequences. Epigenetic regulations include, 1. DNA methylation: the addition of methyl group to DNA, converting cytosine to 5-methylcytosine, mostly at CpG sites; 2. Histone modifications: posttranslational modificationEpigeneticss of histone proteins including acetylation, methylation, ubiquitylation, phosphorylation and sumoylation; 3. miRNAs: non-coding microRNA downregulating gene expression; 4. Prions: infectious proteins viewed as epigenetic agents capable of inducing a phenotype without changing the genome.
- Bromodomain(50)
- Aurora Kinase(63)
- DNA Methyltransferase(35)
- HDAC(210)
- Histone Acetyltransferases(78)
- Histone Demethylases(110)
- Histone Methyltransferase(240)
- HIF(102)
- JAK(173)
- MBT Domains(1)
- PARP(122)
- Pim(32)
- Protein Ser/Thr Phosphatases(34)
- RNA Polymerase(7)
- Sirtuin(77)
- Sphingosine Kinase-2(1)
- Polycomb repressive complex(2)
- SUMOylation(3)
- PAD(21)
- Epigenetic Reader Domain(246)
- MicroRNA(24)
- Protein Arginine Deiminase(7)
- Chromodomain(1)
- Citrullination(20)
- DNA/RNA Demethylation(2)
- DNA/RNA Methylation(8)
- Histone Deacetylation(44)
- Histones/Histone Peptides(62)
- PHD Domains(1)
- Tandem Tudor & Tudor-like Domains(1)
- PRMT(2)
- Readers(1)
- Small Interfering RNA (siRNA)(1)
- METTL3(2)
- WDR5(1)
- TET Protein(2)
- HuR(1)
- SF3B1(1)
Chromatin/Epigenetics 相关产品(1617)
- GC42790AmodiaquineCAS: 86-42-0纯度: >98.00%
Amodiaquine是一种4-氨基喹啉类化合物，主要用于疟疾的治疗，还具有抗炎、抗病毒作用。Amodiaquine是一种核受体Nurr1激动剂，EC 50 值约为20μM。
- GC42944BIX01294 (hydrochloride hydrate)CAS: 1808255-64-2纯度: >98.00%
An inhibitor of G9a histone methyltransferase
- GC43275Citrulline-specific Probe-RhodamineCAS: 2309313-01-5纯度: >90.00%
A fluorophore that detects protein citrullination
- GC43406Delphinidin (chloride)CAS: 528-53-0纯度: >97.00% / >98.00%
Delphinidin (chloride) 是一种常见的花青素单体形式之一，可以从浆果和红酒中分离得到。
- GC43715Furamidine (hydrochloride)CAS: 55368-40-6纯度: >98.00%
A selective PRMT1 inhibitor and antiprotozoal agent
- GC43789GSK199 (hydrochloride)CAS: 1549811-53-1纯度: >98.00%
GSK199 (hydrochloride)是一种具有口服活性和可逆性的选择性肽基精氨酸脱亚氨酶4（PAD4）抑制剂，在缺少钙离子情况下IC 50 值为200nM。
- GC43826Histone H2A (1-20) (human, mouse, rat, bovine) (trifluoroacetate salt)纯度: >95.00%
A peptide fragment of histone H2A
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC42790 | Amodiaquine | 86-42-0 | >98.00% | |
Amodiaquine是一种4-氨基喹啉类化合物，主要用于疟疾的治疗，还具有抗炎、抗病毒作用。Amodiaquine是一种核受体Nurr1激动剂，EC 50 值约为20μM。 | ||||
| GC42910 | BB-F-Yne | 2219331-30-1 | >98.00% | |
A clickable PAD inhibitor | ||||
| GC42933 | Binucleine 2 | 220088-42-6 | >98.00% | |
An inhibitor of Drosophila Aurora B kinase | ||||
| GC42944 | BIX01294 (hydrochloride hydrate) | 1808255-64-2 | >98.00% | |
An inhibitor of G9a histone methyltransferase | ||||
| GC43147 | CAY10398 | 193551-00-7 | >98.00% | |
A potent, cost-effective histone deacetylase inhibitor | ||||
| GC43192 | CAY10685 | 1613116-16-7 | >98.00% | |
A “clickable” analog of CPTH2 | ||||
| GC43200 | CAY10721 | 848688-62-0 | >98.00% | |
An inhibitor of SIRT3 | ||||
| GC43201 | CAY10722 | 388086-13-3 | >98.00% | |
A SIRT3 inhibitor | ||||
| GC43202 | CAY10723 | 2095107-57-4 | >98.00% | |
A PAD2 inhibitor | ||||
| GC43275 | Citrulline-specific Probe-Rhodamine | 2309313-01-5 | >90.00% | |
A fluorophore that detects protein citrullination | ||||
| GC43318 | coumarin-SAHA | 1260635-77-5 | >98.00% | |
A fluorescent probe for HDAC | ||||
| GC43320 | CPI-268456 | 1380087-86-4 | >98.00% | |
A ligand of BRD4 | ||||
| GC43321 | CPTH6 (hydrobromide) | 2321332-57-2 | >98.00% | |
A Gcn5 and pCAF HAT inhibitor | ||||
| GC43354 | Cysmethynil | 851636-83-4 | >98.00% | |
An inhibitor of protein prenylation | ||||
| GC43406 | Delphinidin (chloride) | 528-53-0 | >97.00% / >98.00% | |
Delphinidin (chloride) 是一种常见的花青素单体形式之一，可以从浆果和红酒中分离得到。 | ||||
| GC43651 | F-Amidine (trifluoroacetate salt) | 877617-46-4 | >95.00% | |
A PAD inhibitor | ||||
| GC43715 | Furamidine (hydrochloride) | 55368-40-6 | >98.00% | |
A selective PRMT1 inhibitor and antiprotozoal agent | ||||
| GC43787 | GSK106 (hydrochloride) | 1652591-82-6 | >98.00% | |
An inactive control for GSK484 and GSK199 | ||||
| GC43788 | GSK121 (trifluoroacetate salt) | 1652591-80-4 | >98.00% | |
A PAD4 inhibitor | ||||
| GC43789 | GSK199 (hydrochloride) | 1549811-53-1 | >98.00% | |
GSK199 (hydrochloride)是一种具有口服活性和可逆性的选择性肽基精氨酸脱亚氨酶4（PAD4）抑制剂，在缺少钙离子情况下IC 50 值为200nM。 | ||||
| GC43792 | GSK-J2 (sodium salt) | 2108665-15-0 | >90.00% | |
A negative control compound for GSK-J1 | ||||
| GC43794 | GSK-J5 (hydrochloride) | 1797983-32-4 | >95.00% | |
A negative control compound for GSK-J4 | ||||
| GC43806 | HC Toxin | 83209-65-8 | >98.00% | |
Potent HDAC inhibitor | ||||
| GC43826 | Histone H2A (1-20) (human, mouse, rat, bovine) (trifluoroacetate salt) | - | >95.00% | |
A peptide fragment of histone H2A | ||||