Signaling Pathways
Signaling Pathways(信号通路)
- Proteases(63)
- Apoptosis(1190)
- Chromatin/Epigenetics(17)
- Metabolism(420)
- MAPK Signaling(32)
- Tyrosine Kinase(97)
- DNA Damage/DNA Repair(62)
- PI3K/Akt/mTOR Signaling(56)
- Microbiology & Virology(68)
- Cell Cycle/Checkpoint(205)
- Ubiquitination/ Proteasome(43)
- JAK/STAT Signaling(13)
- TGF-β / Smad Signaling(30)
- Angiogenesis(85)
- GPCR/G protein(3)
- Stem Cell(27)
- Membrane Transporter/Ion Channel(273)
- Cancer Biology(514)
- Endocrinology and Hormones(168)
- Neuroscience(462)
- Obesity, Appetite Control & Diabetes(9)
- Peptide Inhibitors and Substrate(1)
- Other Signal Transduction(141)
- Immunology/Inflammation(1111)
- Cardiovascular(63)
- Vitamin D Related
- Antibody-drug Conjugate/ADC Related
- PROTAC(254)
- Ox Stress Reagents(25)
- Others(1718)
- Antiparasitics(21)
- Toxins(90)
Signaling Pathways 相关产品(35130)
- GC13733A 438079 hydrochlorideCAS: 899431-18-6纯度: >99.50%
An antagonist of the nucleotide receptor P2X7
- GC13761AZD8931 (Sapitinib)CAS: 848942-61-0纯度: >99.50%
A reversible inhibitor of ErbB1/EGFR, ErbB2/HER2, and ErbB3/HER3
- GC13771CanagliflozinCAS: 842133-18-0纯度: >99.50% / >98.00%
Canagliflozin是一种用于治疗2型糖尿病的钠葡萄糖共转运体(SGLT2)抑制剂。
- GC13779Orphenadrine CitrateCAS: 4682-36-4纯度: >98.00%
Orphenadrine citrate 是一种具有口服活性且非竞争性的 NMDA 受体拮抗剂(穿过血脑屏障),Ki 为 6.0 μM。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC13673 | BMS-708163 (Avagacestat) | 1146699-66-2 | >98.00% | |
A potent inhibitor of γ-secretase | ||||
| GC13683 | Rivaroxaban | 366789-02-8 | >99.50% | |
A selective inhibitor of Factor Xa | ||||
| GC13694 | Spermine NONOate | 136587-13-8 | >98.00% | |
A nitric oxide donor | ||||
| GC13697 | AG-1024 | 65678-07-1 | >98.50% | |
AG-1024是一种可逆的,竞争性和选择性的胰岛素样生长因子-1受体(IGF-1R)抑制剂,IC 50 值为7μM。AG-1024能够抑制胰岛素受体(IR)的磷酸化,IC 50 值为57μM。 | ||||
| GC13698 | Nilvadipine | 75530-68-6 | >99.50% | |
An L-type calcium channel blocker | ||||
| GC13705 | BMS-927711 | 1289023-67-1 | >99.00% | |
A CGRP receptor antagonist | ||||
| GC13706 | Droxinostat | 99873-43-5 | >99.50% | |
An inhibitor of HDAC3, HDAC6, and HDAC8 | ||||
| GC13716 | Lopinavir | 192725-17-0 | >99.50% / >99.00% | |
A potent HIV-1 protease inhibitor | ||||
| GC13723 | Amitriptyline HCl | 549-18-8 | >99.50% | |
A tricyclic antidepressant | ||||
| GC13725 | NVP-BAG956 | 853910-02-8 | - | |
A dual PDK1 and class I PI3K inhibitor | ||||
| GC13729 | Cytidine | 65-46-3 | >99.50% / >98.00% | |
A pyrimidine nucleoside | ||||
| GC13730 | Alfuzosin HCl | 81403-68-1 | >98.50% | |
α 1 -Adrenergic receptor antagonist | ||||
| GC13733 | A 438079 hydrochloride | 899431-18-6 | >99.50% | |
An antagonist of the nucleotide receptor P2X7 | ||||
| GC13747 | Vilanterol | 503068-34-6 | - | |
A β 2 -AR agonist | ||||
| GC13750 | Doxycycline HCl | 10592-13-9 | - | |
Doxycycline HCl 是一种抗生素,是一种具有口服活性的广谱金属蛋白酶 (MMP) 抑制剂。 | ||||
| GC13753 | Flucytosine | 2022-85-7 | >99.50% | |
A prodrug of 5-fluorouracil | ||||
| GC13756 | Olsalazine Sodium | 6054-98-4 | >99.50% | |
A prodrug form of 5-aminosalicylic acid | ||||
| GC13761 | AZD8931 (Sapitinib) | 848942-61-0 | >99.50% | |
A reversible inhibitor of ErbB1/EGFR, ErbB2/HER2, and ErbB3/HER3 | ||||
| GC13771 | Canagliflozin | 842133-18-0 | >99.50% / >98.00% | |
Canagliflozin是一种用于治疗2型糖尿病的钠葡萄糖共转运体(SGLT2)抑制剂。 | ||||
| GC13779 | Orphenadrine Citrate | 4682-36-4 | >98.00% | |
Orphenadrine citrate 是一种具有口服活性且非竞争性的 NMDA 受体拮抗剂(穿过血脑屏障),Ki 为 6.0 μM。 | ||||
| GC13783 | Phenserine | 101246-66-6 | >98.00% | |
An AChE inhibitor | ||||
| GC13792 | Rufinamide | 106308-44-5 | >99.50% | |
An anticonvulsant | ||||
| GC13793 | NH125 | 278603-08-0 | >98.00% | |
NH125是一种多靶标的活性物质,是多种组氨酸蛋白激酶家族成员的抑制剂,其中NH125可抑制真核延长因子2激酶(eEF-2K)活性,IC 50 =60nM。 | ||||
| GC13799 | Alfacalcidol | 41294-56-8 | >99.00% | |
Prodrug of vitamin D 3 | ||||
