Signaling Pathways
Signaling Pathways(信号通路)
- Proteases(63)
- Apoptosis(1190)
- Chromatin/Epigenetics(17)
- Metabolism(420)
- MAPK Signaling(32)
- Tyrosine Kinase(97)
- DNA Damage/DNA Repair(62)
- PI3K/Akt/mTOR Signaling(56)
- Microbiology & Virology(68)
- Cell Cycle/Checkpoint(205)
- Ubiquitination/ Proteasome(43)
- JAK/STAT Signaling(13)
- TGF-β / Smad Signaling(30)
- Angiogenesis(85)
- GPCR/G protein(3)
- Stem Cell(27)
- Membrane Transporter/Ion Channel(273)
- Cancer Biology(514)
- Endocrinology and Hormones(168)
- Neuroscience(462)
- Obesity, Appetite Control & Diabetes(9)
- Peptide Inhibitors and Substrate(1)
- Other Signal Transduction(141)
- Immunology/Inflammation(1111)
- Cardiovascular(63)
- Vitamin D Related
- Antibody-drug Conjugate/ADC Related
- PROTAC(254)
- Ox Stress Reagents(25)
- Others(1718)
- Antiparasitics(21)
- Toxins(90)
Signaling Pathways 相关产品(35130)
- GC13814Adrenalone HClCAS: 62-13-5纯度: >98.00%
Decoyinine (Angustmycin A), a specific inhibitor of bacterial GMPS, has been isolated from Streptomyces .
- GC13826JAK2 Inhibitor V, Z3CAS: 195371-52-9
A selective inhibitor of the autophosphorylation of wild type and V617F mutant forms of JAK
- GC13842Ro 20-1724CAS: 29925-17-5纯度: >98.00% / >95.00%
Ro 20-1724是一种选择性cAMP特异性磷酸二酯酶(PDE4)抑制剂,IC 50 值为1.930μM。
- GC13854AG-490 (Tyrphostin B42)CAS: 133550-30-8纯度: >98.00%
AG-490 (Tyrphostin B42)是EGFR抑制剂,IC50为0.1 µM, AG-490对JAK2也有抑制作用。
- GC13856Dalcetrapib (JTT-705, RO4607381)CAS: 211513-37-0纯度: >99.00%
An inhibitor of cholesteryl ester transfer protein
- GC13873BMS-690514CAS: 859853-30-8纯度: >99.50%
BMS-690514 是一种有效的、具有口服活性的 EGFR 和 VEGFR 抑制剂;对 EGFR、HER 2 和 HER 4 的 IC50 分别为 5、20 和 60 nM。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC13802 | Riluzole | 1744-22-5 | >98.00% | |
Riluzole 是一种抗惊厥药,属于使用依赖性 Na+ 通道阻滞剂家族,它也可以抑制 GABA 摄取,IC50 为 43 μM。 | ||||
| GC13803 | Triflurdine (Viroptic) | 70-00-8 | >99.50% | |
A thymidine analog that inhibits DNA synthesis | ||||
| GC13805 | Abacavir | 136470-78-5 | >99.50% | |
阿巴卡韦是一种具有口服活性和竞争性的核苷类逆转录酶抑制剂。 | ||||
| GC13814 | Adrenalone HCl | 62-13-5 | >98.00% | |
Decoyinine (Angustmycin A), a specific inhibitor of bacterial GMPS, has been isolated from Streptomyces . | ||||
| GC13824 | Indapamide | 26807-65-8 | >99.50% / >98.00% | |
An Analytical Reference Standard | ||||
| GC13826 | JAK2 Inhibitor V, Z3 | 195371-52-9 | - | |
A selective inhibitor of the autophosphorylation of wild type and V617F mutant forms of JAK | ||||
| GC13830 | Baricitinib phosphate | 1187595-84-1 | >99.50% | |
A JAK1 and JAK2 inhibitor | ||||
| GC13831 | FT-207 (NSC 148958) | 17902-23-7 | >99.50% | |
A prodrug form of 5-fluorouracil | ||||
| GC13835 | Toremifene Citrate | 89778-27-8 | >99.50% | |
A selective estrogen receptor modulator | ||||
| GC13837 | SNS-314 Mesylate | 1146618-41-8 | >99.50% | |
A pan-Aurora kinase inhibitor | ||||
| GC13841 | JNK-IN-8 | 1410880-22-6 | >99.50% | |
JNK-IN-8 是第一个不可逆的JNK抑制剂,作用于JNK1,JNK2和JNK3,具有高度特异性,在A375细胞系中IC50分别为4.7 nM,18.7 nM和1 nM。 | ||||
| GC13842 | Ro 20-1724 | 29925-17-5 | >98.00% / >95.00% | |
Ro 20-1724是一种选择性cAMP特异性磷酸二酯酶(PDE4)抑制剂,IC 50 值为1.930μM。 | ||||
| GC13843 | Pyrazinamide | 98-96-4 | >99.50% | |
An antimycobacterial compound | ||||
| GC13846 | Tenofovir hydrate | 206184-49-8 | >98.00% | |
An HIV and HBV antiviral | ||||
| GC13848 | LY2784544 | 1229236-86-5 | >99.50% | |
Potent inhibitor of JAK2 | ||||
| GC13853 | GBR 12935 dihydrochloride | 67469-81-2 | >98.00% | |
An inhibitor of dopamine uptake | ||||
| GC13854 | AG-490 (Tyrphostin B42) | 133550-30-8 | >98.00% | |
AG-490 (Tyrphostin B42)是EGFR抑制剂,IC50为0.1 µM, AG-490对JAK2也有抑制作用。 | ||||
| GC13856 | Dalcetrapib (JTT-705, RO4607381) | 211513-37-0 | >99.00% | |
An inhibitor of cholesteryl ester transfer protein | ||||
| GC13860 | Gatifloxacin mesylate | 316819-28-0 | - | |
A fluoroquinolone antibiotic | ||||
| GC13861 | Levofloxacin | 100986-85-4 | >99.50% / >98.00% | |
A fluoroquinolone antibiotic | ||||
| GC13863 | 10Panx | 955091-53-9 | >98.00% | |
10Panx是一种强效的Panx1通道抑制剂,靶向Panx1蛋白ECL1结构域中的W74至Y83片段。 | ||||
| GC13871 | Duloxetine HCl | 136434-34-9 | >99.50% | |
A serotonin and norepinephrine reuptake inhibitor | ||||
| GC13873 | BMS-690514 | 859853-30-8 | >99.50% | |
BMS-690514 是一种有效的、具有口服活性的 EGFR 和 VEGFR 抑制剂;对 EGFR、HER 2 和 HER 4 的 IC50 分别为 5、20 和 60 nM。 | ||||
| GC13878 | EPZ005687 | 1396772-26-1 | >99.00% | |
A potent, selective inhibitor of EZH2 | ||||
