Signaling Pathways(信号通路)

Cat.No. 产品名称 Information

GC38007 β-Melanocyte Stimulating Hormone (MSH), human TFA

Beta-MSH (1-22) (human) TFA

β-Melanocyte Stimulating Hormone (MSH), human TFA, 是一个 22 肽，是一种内源性黑皮质素-4 受体 (melanocortin-4 receptor; MC4-R) 激动剂。

GC66842 β-Methylcrotonyl coenzyme A lithium β-Methylcrotonyl coenzyme A lithium 是亮氨酸代谢的中间体，可被用作底物来研究 β-甲基巴豆酰辅酶 A 羧化酶 (MCCase) 的特异性和动力学。

GC40719 β-Muricholic Acid

Β-鼠胆酸,5β-Cholanic Acid-3α,6β,7β-triol, β-MCA

β-胆酸β-muricholic acid是一种天然存在的三羟基亲水性胆汁酸，作为胆道胆固醇去饱和剂，促进胆固醇胆结石的溶解。

GC49007 β-Muricholic Acid-d4

ω-MCA-d4

An internal standard for the quantification of β-muricholic acid

GC41502 β-Myrcene

月桂烯; β-Myrcene

A terpene with antioxidative properties

GC70184 β-Naphthoflavone-CH2-Br

β-NF-CH2-Br

β-Naphthoflavone-CH2-Br 是一种芳香烃受体 (AhR) 配体。β-Naphthoflavone-CH2-Br 用于合成 PROTACβ-NF-JQ1 。

GC67484 β-Nicotinamide adenine dinucleotide reduced dipotassium β-Nicotinamide adenine dinucleotide reduced dipotassium 是一种口服有效的还原型辅酶。β-Nicotinamide adenine dinucleotide reduced dipotassium 还是 ADP-核糖基转移酶反应中的 ADP-核糖单元的供体和环状 ADP-核糖的前体。β-Nicotinamide adenine dinucleotide reduced dipotassium 在细胞的能量代谢过程中起到再生电子供体的作用，包括糖酵解，β-氧化和三羧酸 (TCA) 循环。

GC72061 β-Phellandrene β-Phellandrene是从岩骨中获得的。

GC45604 β-Rubromycin

BETA-玉红霉素

A bacterial metabolite

GC70185 β-Sitostenone

δ4-Sitosterol-3-one; β-Rosasterol oxide

β-Sitostenone 是一种从 Cochlospermum vitifolium 中分离得到的甾醇。β-Sitostenone 可抑制酪氨酸酶 (tyrosinase) 活性，并具有抗黑色素生成和抗肿瘤活性。

GC38008 β-Zearalenol

Β-玉米赤霉烯醇,β-trans-Zearalenol, (-)-β-Zearalenol

A hepatic metabolite of zearalenone

GC37983 β3-AR agonist 1 β3-AR agonist 1 (compound 15) 是一种高效选择性的，可口服的 β3-肾上腺素能受体 (β3-AR) 激动剂 (EC50=18 nM)，对 β1-、β2-、α1A-AR 无活性 (β1/β3, β2/β3, α1A/β3>556倍)。

GC40105 βARK1 Inhibitor

呋喃妥因-13C3

An inhibitor of GRK2/βARK1

GC70650 γ-Acetylenic GABA hydrochloride γ-Acetylenic GABA hydrochloride是GABA转氨酶的不可逆抑制剂。

GC38010 γ-Aminobutyric acid

γ-氨基丁酸

γ-氨基丁酸（γ-Aminobutyric acid，GABA）是成人大脑中的主要抑制性神经递质。

GC64508 γ-Aminobutyric acid-d6

4-氨基丁酸-2,2,3,3,4,4-D6,4-Aminobutyric acid-d6

γ-Aminobutyric acid-d6 (4-Aminobutyric acid-d6) 是 γ-Aminobutyric acid 的氘代物。γ-Aminobutyric acid (4-Aminobutyric acid) 是成年哺乳动物大脑中主要的抑制性神经递质，能够与离子移变 GABA 受体 (GABAA) 受体和促代谢受体 (GABAB) 受体结合发挥作用。

GC40551 γ-CEHC

γTocopherol Metabolite, GTM, 2,7,8trimethyl2(βCarboxyEthyl)6Hydroxychroman

A β-oxidized metabolite of dietary γ-tocopherol

GC49865 γ-D-Glutamylglycine (trifluoroacetate salt)

γ-DGG

An excitatory amino acid antagonist

GC52400 γ-Glu-Ala (trifluoroacetate salt)

γ-Glutamylalanine, γ-L-Glutamyl-L-alanine

A dipeptide

GC48312 γ-Glu-Cys (ammonium salt)

γ-Glutamylcysteine

An intermediate in GSH synthesis

GC63279 γ-Glu-Gly TFA γ-Glu-Gly 是一种 γ-谷氨酰二肽，是一种人体脂质代谢物。γ-Glu-Gly 与 GABA (γ-氨基丁酸)结构相似，可作为兴奋性氨基酸的拮抗剂。

GC52404 γ-Glu-Phe (trifluoroacetate salt)

γ-Glutamylphenylalanine

A dipeptide with metabolism-altering activity

GC70186 γ-Glutamylornithine γ-Glutamylornithine 是 HHH 综合征 (高尿酸血症、高氨血症和高瓜氨酸尿症) 和与高尿酸症相关的回转性萎缩患者的尿液排泄物。内源性鸟氨酸增加会增加 γ-Glutamylornithine 在尿液中的水平。

GC70796 γ-Glutamylserine γ-Glutamylserine（γ-Glu-Ser）是一种钙受体激活剂。

GC63280 γ-Hexalactone

γ-己内酯; γ-Caprolactone

γ-caprolactone is well-known as a food flavor and is a biostimulant molecule promoting the growth of bacteria with biocontrol activity against soft-rot pathogens.

GC48313 γ-Lindane

林丹(R-六六六)

An insecticide and GABA_A receptor antagonist

GC38011 γ-Secretase modulator 4 γ-Secretase modulator 4 是一种有效的 γ- 分泌酶调节剂 (γ-secretase)，在人类和小鼠中降低 Aβ42 产生的 IC50 值分别为 0.014 μM 和 0.017 μM。

GC41503 γ-Terpinene

γ-松油烯

A monoterpene with diverse biological activities

GC17002 γ1-MSH γ1-MSH 是一种黑皮质素 MC3 受体激动剂，对大鼠 MC3 受体的 Ki 值为 34 nM。

GC92102 γ1-MSH (human, mouse, rat, bovine) (acetate)

γ₁-Melanocyte-stimulating Hormone

γ1-MSH (human, mouse, rat, bovine) (acetate)是一种肽激素，由垂体中的前皮黑皮质素（POMC）翻译后加工产生。

GC92101 γ1-MSH (human, mouse, rat, bovine) (trifluoroacetate salt)

γ₁-Melanocyte-stimulating Hormone

γ1-MSH (human, mouse, rat, bovine) (trifluoroacetate salt)是一种肽激素，由垂体中的前皮黑皮质素（POMC）翻译后加工产生。

GC41596 δ-CEHC

γTocopherol Metabolite, GTM, 2,7,8trimethyl2(βCarboxyEthyl)6Hydroxychroman

A major metabolite of δ-tocopherol

GC66048 δ-Secretase inhibitor 11 Compound 11, a non-toxic and selective δ-secretase inhibitor (IC50=0.7 μM, in fluorescence-based assay) that interacts with both the active site and allosteric site of δ-secretase in Co-crystal structure analysis. The IC50 value of the compound 11 towards δ-secretase in Pala cells is 0.8 μM.

GC41109 δ12-Prostaglandin J2

Δ12-PGJ2

A PGD₂ metabolite with antitumor and antiviral activity

GC45238 δ14-Triamcinolone acetonide

曲安奈德杂质1

A potential impurity found in commercial triamcinolone acetonide preparations

GC40635 δ2-Avermectin B1a An ivermectin B_1a degradation product

GC40307 δ2-cis-Hexadecenoic Acid An unusual fatty acid associated with biosensing bacteria

GC40819 δ2-Doramectin A doramectin degradation product

GC45239 δ4-Abiraterone

阿比特龙代谢物,Δ4-Abiraterone; CB-7627; Abiraterone D4A metabolite

An active metabolite of abiraterone

GC48317 δ7-Avenasterol

豆甾醇杂质2

A phytosterol that has antioxidant activities

GC90882 ε-NAADP+ (sodium salt)

Etheno-NAADP, N6-Ethenoadenine dinucleotide phosphate, Nicotinic Acid adenine dinucleotide phosphate, β-Nicotinic Acid-1

一种荧光衍生物NAADP

GC90812 ε-NAD+ (sodium salt)

N6-Ethenoadenine dinucleotide, β-Nicotinamide-1, ε-Nicotinamide adenine dinucleotide

一种用于检测NAD+依赖酶的荧光探针。

GC90814 ε-NADP+ (sodium salt)

N6-Ethenoadenine dinucleotide phosphate, β-Nicotinamide-1, ε-Nicotinamide adenine dinucleotide phosphate

一种荧光衍生物NADP⁺

GC48532 ε-Rhodomycinone

NSC 196524

A bacterial metabolite and precursor to rhodomycin D

GC62708 σ1 Receptor antagonist-1 WQ 1 is a high affinity and selective σ1 receptor antagonist with pKi values of 10.85, 6.53 and 5.80 at σ1, σ2 receptors and dopamine transporter (DAT), displaying σ1/σ2 selectivity ratio of 20893.