Pain Research(疼痛研究)

Cat.No. 产品名称 Information

GC47314 Ethopropazine (hydrochloride)

盐酸乙丙嗪,Isothazine hydrochloride; Lysivane hydrochloride; Parsidol hydrochloride

A BChE inhibitor

GC47323 Etofenamate-d4

依托芬那酯 d4

An internal standard for the quantification of etofenamate

GC91921 Fenclofenac

RX-67408

Fenclofenac是一种非甾体抗炎药（NSAID）和COX抑制剂（COX-1和COX-2的IC50分别为7和4μM）。

GC47336 Fenobam (hydrate) A noncompetitive antagonist and inverse agonist of mGluR5

GC91909 Fenoprofen-13C6 (sodium salt hydrate) Fenoprofen-13C6 (sodium salt hydrate)旨在用作通过GC或LC-MS定量非诺洛芬的内标。

GC49747 Flunixin-d3

氟尼辛-D3

An internal standard for the quantification of flunixin

GC45761 Flupirtine-d4 (hydrochloride)

D 9998-d4 hydrochloride

An internal standard for the quantification of flupirtine

GC47388 Gabapentin-d4

加巴喷丁 d4

An internal standard for the quantification of gabapentin

GC49154 Galanin (2-11) amide (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

AR-M1896, Gal(2-11)-NH2, WTLNSAGYLL-NH2

A synthetic peptide fragment of galanin and an agonist of the GAL₂ receptor

GC48326 Galanin (Human) (Acetate)

GAL (human), Galanin (1-30)

A neuropeptide and GAL receptor agonist

GC43724 Galanin (rat, mouse) (trifluoroacetate salt)

GAL (rat, mouse)

A neuropeptide with diverse biological activities

GC43738 GAT211 A CB₁ receptor agonist and PAM

GC43774 Glycerophospho-N-Arachidonoyl Ethanolamine

Glycerophosphoanandamide, GlycerophosphoArachidonoyl Ethanolamide, GPNArE

Precursor of anandamide

GC49509 Glycyl-L-Glutamine (hydrate)

甘氨酰-L-谷氨酰胺

A dipeptide fragment of β-endorphin

GC18181 GW 405833

1-(2,3-二氯苯甲酰基)-5-甲氧基-2-甲基-3-[2-(4-吗啉基)乙基]-1H-吲哚,L768242

A selective CB₂ partial agonist

GC49882 Hemokinin 1 (human) (trifluoroacetate salt)

HK-1, TGKASQFFGLM-NH2, Thr-Gly-Lys-Ala-Ser-Gln-Phe-Phe-Gly-Leu-Met-NH2

A peptide agonist of NK₁ receptors

GC19903 HISPOLON(P)

Hispolon

GC48453 Hodgkinsine

(-)-Hodgkinsine

An alkaloid with analgesic activity

GC48454 Hodgkinsine B

(-)-Hodgkinsine B

An alkaloid with analgesic activity

GC92103 HS-014 (trifluoroacetate salt)

Cyclic [Ac-Cys¹¹, D-Nal¹⁴, Cys¹⁸, Asp-NH₂]-β-MSH(11-22)

HS-014 (trifluoroacetate salt)是黑素皮质素受体4mc4r的拮抗剂；Ki = 3.16 nM。

GC92098 HS-024 (trifluoroacetate salt)

Ac-Cys-Nle-Arg-His-D-Nal-Arg-Trp-Gly-Cys-NH₂; cyclic [AcCys³,Nle⁴,Arg⁵,D-Nal⁷,Cys-NH₂¹¹]α-MSH-(3-11)

HS-024 (trifluoroacetate salt)是黑皮质素受体4的环肽拮抗剂（MC4R；Ki=0.29nM）。

GC49559 Hydroxymethyl Tolperisone (hydrochloride) A metabolite of tolperisone

GC43891 IDFP

Isopropyl Dodecylfluorophosphonate

An MAGL and FAAH inhibitor

GC52154 Inflammasome Inhibitor 4b An inhibitor of NLRP3 inflammasome activation

GC43906 Iperoxo (iodide) An agonist of muscarinic acetylcholine receptors

GC47471 Isoxsuprine-d6 (hydrochloride)

异舒普林盐酸盐 d6 (盐酸盐)

A neuropeptide with diverse biological activities

GC60211 JNJ-42226314 JNJ-42226314 是一种竞争性，高度选择性和可逆的非共价单酰甘油脂肪酶 MAGL 抑制剂。JNJ-42226314 可剂量依赖性增强主要的内源性大麻素 2-花生四烯酰甘油 (2-AG)，在神经性和炎性疼痛模型中表现出抗伤害作用。

GC47524 Kallidin (380-389) (human, porcine, bovine) (trifluoroacetate salt)

KRPPGFSPFR, Lys-BK, Lysine Bradykinin

具有多种生物活性的神经肽

GC47528 Ketorolac (calcium salt)

酮咯酸钙盐,RS37619 hemicalcium

An NSAID and COX inhibitor

GC52020 Lamotrigine-d3

拉莫三嗪-[D3]

An internal standard for the quantification of lamotrigine

GC49608 Larixyl Acetate

Larixol Acetate

A diterpenoid with TRPC6 inhibitory and analgesic activities

GC49720 Leu-Enkephalin (trifluoroacetate salt)

Leucine enkephalin, Leu5enkephalin, Tyr-Gly-Gly-Phe-Leu-OH

A neuropeptide and δ- and ?-opioid receptor agonist

GC49525 Lidocaine-d10

利多卡因 d10

An internal standard for the quantification of lidocaine

GC45794 Linaclotide-d4 A neuropeptide with diverse biological activities

GC47568 Linoleoyl Ethanolamide-d4

LEA-d4

An internal standard for the quantification of linoleoyl ethanolamide

GC48639 Lornoxicam-d4

氯诺昔康-D4,Chlortenoxicam-d4; Ro 13-9297-d4

An internal standard for the quantification of lornoxicam

GC91681 Loxoprofen-SRS Loxoprofen-SRS is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 0.5 and 0.39 for recombinant human COX-1 and COX-2, respectively) and an active metabolite of the prodrug loxoprofen .

GC39256 LP-935509 LP-935509 是一种小分子衔接蛋白-2 相关激酶1 (AAK1) 选择性和脑渗透抑制剂 (IC50=3.3 nM)，一种 ATP 竞争性抑制剂，其 Ki 为 0.9 nM。 LP-935509 是 BIKE 的有效抑制剂 (IC50=14 nM) 和适度的 GAK 抑制剂 (IC50=320 nM)。 LP-935509 可逆转 SNL 手术后的疼痛。