Nociceptin is a 17 amino acid neuropeptide involved in a variety of biological systems including pain, memory, stress responses, anxiety, locomotion, and feeding behavior.1 It is an endogenous ligand of the NOP1 (ORL1) receptor (Ki = 88 μM in CHO cells) and, though an opioid-
1.Mogil, J.S., and Pasternak, G.W.The molecular and behavioral pharmacology of the orphanin FQ/nociceptin peptide and receptor familyPharmacol. Rev.53(3)381-415(2001)
















