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Home >> Signaling Pathways >> Membrane Transporter/Ion Channel

Membrane Transporter/Ion Channel(跨膜转运)

  1. Cat.No. 产品名称 Information
  2. GC14764 Lamotrigine

    拉莫三嗪; LTG; BW430C

     An anticonvulsant
  3. GC15178 Hexamethonium Bromide

    六甲溴铵

     A nondepolarizing neuromuscular blocking agent
  4. GC16585 Golgicide A

    GCA

     Golgicide A是一种高度特异且可逆的顺式高尔基体ADP-核糖基化因子鸟嘌呤核苷酸交换因子（ArfGEF GBF1）抑制剂，Golgicide A通过选择性靶向GBF1并减少Arf1的活化，从而阻断细胞内的囊泡运输和蛋白质分泌。
  5. GC16561 Gliquidone

    格列喹酮; AR-DF 26

     A second generation sulfonylurea
  6. GC17173 Felodipine

    非洛地平

     An L-type calcium channel inhibitor
  7. GC10861 Domiphen Bromide

    溴化度米芬

     A quaternary ammonium compound and cationic surfactant with antimicrobial activity
  8. GC16622 Dexlansoprazole

    右旋兰索拉唑; Dexlansoprazole

     A proton pump inhibitor
  9. GC16354 Dequalinium Chloride

    地喹氯铵

     An ammonium cation with diverse biological activities
  10. GC16255 Decamethonium Bromide

    十烃溴铵

     A depolarizing neuromuscular blocking agent
  11. GC11120 Ciclopirox ethanolamine

    环吡酮乙醇胺盐; Ciclopirox ethanolamine; HOE 296

     An iron chelator, antifungal, and anticancer agent
  12. GC17086 Chlorpropamide

    氯磺丙脲

     A first generation sulfonylurea
  13. GC14421 CFTRinh-172

    CFTR(inh)172, Cystic Fibrosis Transmembrane Conductance Regulator Inhibitor 172

     CFTRinh-172被鉴定为囊性纤维化跨膜传导调节因子(CFTR)Cl-通道强效的选择性阻断剂。CFTRinh-172对野生型、G551D和G1349D CFTR的Cl-电流具有抑制作用，Ki值为0.5μM。
  14. GC17683 Brefeldin A

    布雷非德菌素 A; BFA; Cyanein; Decumbin

     Brefeldin A（BFA）是一种真菌大环内酯，能够有效、可逆地抑制内质网和高尔基体之间的蛋白质运输和囊泡形成。
  15. GC13125 Benzocaine

    苯佐卡因

     An Analytical Reference Standard
  16. GC14339 Benzethonium Chloride

    苄索氯铵

     Benzethonium chloride 抑制非洲爪蟾卵母细胞中的人重组 α7 和 α4β2 神经元烟碱乙酰胆碱受体。
  17. GC12414 Bemegride

    贝美格; 3-Ethyl-3-methylglutarimide; Bemegrid

     Bemegride (3-Ethyl-3-methylglutarimide) 是一种中枢神经系统兴奋剂和巴比妥类中毒的解毒剂。
  18. GC13723 Amitriptyline HCl

    盐酸阿米替林

     A tricyclic antidepressant
  19. GC15458 Ambroxol HCl

    盐酸氨溴索,NA-872 hydrochloride

     An expectorant
  20. GC13430 (-)-Blebbistatin

    (S)-(-)-Blebbistatin

     (-)-Blebbistatin是外消旋体混合物(±)-Blebbistatin（货号：GC12341）的一种其中一个构型，是活性形式。(-)-Blebbistatin是一种非肌肉肌球蛋白II ATP酶的细胞渗透性抑制剂，有效抑制多种横纹肌肌球蛋白以及脊椎动物非肌肉肌球蛋白，IC50值范围为0.5-5μM，平滑肌肌球蛋白仅受到微弱抑制（IC50=80μM）。
  21. GC14792 Reserpine hydrochloride

    利血平盐酸盐

     Irreversible inhibitor of VMAT1 and VMAT2
  22. GC14703 Oxybutynin chloride

    盐酸奥昔布宁

     An antagonist of muscarinic acetylcholine receptors
  23. GC13824 Indapamide

    吲达帕胺

     An Analytical Reference Standard
  24. GC17340 Carbamazepine

    卡马西平; CBZ; NSC 169864

     卡马西平是一种钠通道阻滞剂，是一种抗惊厥药。
  25. GC11213 Trichlormethiazide

    三氯噻嗪

     A thiazide diuretic
  26. GC15363 Felbamate hydrate

    W-554 hydrate; ADD-03055 hydrate

     An inhibitor of NMDA receptors and a modulator of GABAA receptors
  27. GC10522 Felbamate

    非尔氨酯; W-554; ADD-03055

     An inhibitor of NMDA receptors and a modulator of GABAA receptors
  28. GC13162 Prilocaine hydrochloride

    盐酸丙胺卡因

     An Analytical Reference Standard
  29. GC15071 Prilocaine

    丙胺卡因

     An Analytical Reference Standard
  30. GC17952 Zonisamide sodium

    唑尼沙胺钠; AD 810 sodium; CI 912 sodium

     A broad-spectrum sulfonamide antiepileptic agent
  31. GC10500 Oxcarbazepine

    奥卡西平; GP 47680

     A prodrug form of 10,11-dihydro-10-hydroxy carbamazepine
  32. GC14977 Minoxidil

    米诺地尔; U10858

     An anti-hypertensive vasodilator
  33. GC15101 Azelnidipine

    阿折地平; CS 905

     A calcium channel blocker
  34. GC17106 Verapamil HCl

    盐酸维拉帕米; (±)-Verapamil hydrochloride; CP-16533-1 hydrochloride

     Verapamil HCl是 L 型钙通道阻滞剂和肾上腺素能受体拮抗剂，常用于高血压、心律失常和心绞痛的研究。
  35. GC17316 Gabapentin HCl

    加巴喷丁盐酸盐

     An approved antiepileptic drug
  36. GC13792 Rufinamide

    卢非酰胺; CGP 33101; E 2080; RUF 331

     An anticonvulsant
  37. GC12234 Dronedarone HCl

    盐酸决奈达隆

     An antiarrhythmic agent
  38. GC17804 GlyH-101

    GlyH101, Cystic Fibrosis Transmembrane Conductance Regulator Inhibitor II

     A reversible CFTR channel blocker
  39. GC10443 Meclofenoxate hydrochloride

    盐酸甲氯酚酯

     A nootropic agent
  40. GC16899 Coluracetam

    考拉西坦; MKC-231

     An Analytical Reference Standard
  41. GC16359 Rosuvastatin

    瑞舒伐他汀; ZD 4522

     Rosuvastatin是一种竞争性HMG-CoA还原酶抑制剂，IC50值为11nM。
  42. GC16128 Clevidipine Butyrate

    氯维地平

     An inhibitor of L-type calcium channels
  43. GC15293 Manidipine 2HCl

    盐酸马尼地平,CV-4093

     An L- and T-type calcium channel blocker
  44. GC16889 Nisoldipine

    尼索地平; BAY-k 5552

     A calcium channel inhibitor
  45. GC11299 Mitiglinide Calcium

    米格列奈钙; KAD-1229 anhydrous; S21403 anhydrous

     A SUR1/Kir6.2 inhibitor
  46. GC14111 (R)-baclofen

    (R)-巴氯芬; Arbaclofen; STX209

     (R)-巴氯芬 (Arbaclofen) 是一种选择性 GABAB 受体激动剂。
  47. GC10599 Esomeprazole Sodium

    埃索美拉唑钠,(S)-Omeprazole sodium; (-)-Omeprazole sodium

     Esomeprazole Sodium是一种强效、具有口服活性的质子泵抑制剂。
  48. GC13375 Dofequidar fumarate

    MS-209

     A quinoline derivative and inhibitor of multidrug resistance
  49. GC11470 Flupirtine maleate

    氟吡啶马来酸

     An activator of Kv7 channels
  50. GC14039 MDL-29951

    An NMDA receptor antagonist and GPR17 agonist
  51. GC13218 TRPC6 inhibitor

    4-[[(1R,2R)-2-[(3R)-3-氨基-1-哌啶基]-2,3-二氢-1H-茚-1-基]氧基]-3-氯苯甲腈二盐酸盐

     A TRPC6 channel blocker

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