GlpBio

Membrane Transporter/Ion Channel

Membrane Transporter/Ion Channel(跨膜转运)

研究方向

Membrane Transporter/Ion Channel 相关产品(2265)

  • GC19025 structure
    GC19025AM-0902
    CAS: 1883711-97-4
    纯度: >99.50%

    AM-0902 是一种有效的选择性瞬时受体电位 A1 (TRPA1) 拮抗剂，对 rTRPA1 和 hTRPA1 的 IC50 分别为 71 和 131 nM。

  • GC19057 structure
    GC19057Basmisanil
    CAS: 1159600-41-5
    纯度: >99.50%

    A negative allosteric modulator of α 5 subunit-containing GABA A receptors

  • GC19107 structure
    GC19107CM-4620
    CAS: 1713240-67-5
    纯度: >99.50% / >98.00%

    CM-4620是一种选择性Orai通道抑制剂，对Orai1和Orai2的IC 50 值分别为0.119μM和0.895μM。

  • GC19152 structure
    GC19152Fantofarone
    CAS: 114432-13-2
    纯度: >99.50%

    A calcium channel inhibitor

  • GC19169 structure
    GC19169GLPG1837
    CAS: 1654725-02-6
    纯度: >99.00%

    A CFTR potentiator

  • GC19183 structure
    GC19183GSK369796 Dihydrochloride
    CAS: 1010411-21-8
    纯度: >98.00%

    An antimalarial agent

  • GC19252 structure
    GC19252MK-8998
    CAS: 953778-58-0
    纯度: >99.50%

    MK-8998 (MK-8998; Compound 33) 是一种有效的选择性 T 型钙通道抑制剂。

  • GC19271 structure
    GC19271ONO-8590580
    CAS: 1802661-73-9
    纯度: >99.00%

    A negative allosteric modulator of α 5 subunit-containing GABA A receptors

  • GC19281 structure
    GC19281PF-01247324
    CAS: 875051-72-2
    纯度: >99.50%

    An inhibitor of Na v 1.8 channels

  • GC19289 structure
    GC19289PF-06869206
    CAS: 2227425-05-8
    纯度: >99.50%

    An NaPi2a inhibitor

  • GC19291 structure
    GC19291PF-4840154
    CAS: 1332708-14-1
    纯度: >99.50%

    A TRPA1 channel agonist

  • GC19310 structure
    GC19310Ro 25-6981
    CAS: 169274-78-6

    A potent, NR2B-selective NMDA receptor antagonist

  • GC19346 structure
    GC19346Talampanel
    CAS: 161832-65-1
    纯度: >98.00%

    An allosteric AMPA receptor antagonist

  • GC19351 structure
    GC19351Tebanicline hydrochloride
    CAS: 203564-54-9

    A potent agonist of neuronal α4β2 subunit-containing nAChRs

  • GC19352 structure
    GC19352Tenapanor
    CAS: 1234423-95-0

    A NHE-3 inhibitor

  • GC19370 structure
    GC19370Valbenazine
    CAS: 1025504-45-3
    纯度: >99.00%

    An inhibitor of VMAT2

  • GC19373 structure
    GC19373Verinurad
    CAS: 1352792-74-5
    纯度: >99.00%

    A URAT1 inhibitor

  • GC19422 structure
    GC19422Gefapixant
    CAS: 1015787-98-0
    纯度: >99.00%

    Gefapixant 是一种具有口服活性的强效嘌呤能 P2X3 受体 (P2X3R) 拮抗剂，与重组 hP2X3 同源三聚体相比，IC50 值约为 30 nM，对 hP2X2/3 异源三聚体受体的 IC50 值为 100-250 nM。

  • GC19438 structure
    GC19438TMB 8 (hydrochloride)
    CAS: 53464-72-5
    纯度: >98.00%

    A non-competitive antagonist of nAChRs and an inhibitor of intracellular calcium availability

  • GC19480 structure
    GC19480AUT1
    CAS: 1311136-84-1
    纯度: >99.50%

    A positive modulator of K v 3.1b, K v 3.2a, and K v 3.3

  • GC19488 structure
    GC19488BAY-8002
    CAS: 724440-27-1

    An inhibitor of MCT1

  • GC19522 structure
    GC19522Sodium oleate
    CAS: 143-19-1
    纯度: >97.00%

    A monounsaturated fatty acid

  • GC19729 structure
    GC19729Adenosine 5′-diphosphoribose sodium
    CAS: 68414-18-6
    纯度: >99.00%

    Adenosine 5′-diphosphoribose sodium是一种核苷酸衍生物，是Transient receptor potential melastatin 2 (TRPM2)激动剂，在细胞内多种代谢途径中发挥着重要作用。

  • GC20027 structure
    GC20027(±)5(6)-DiHET MaxSpec® Standard
    CAS: 213382-49-1
    纯度: >95.00%

    5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET by epoxide hydrolases.