GlpBio

Membrane Transporter/Ion Channel

Membrane Transporter/Ion Channel(跨膜转运)

研究方向

Membrane Transporter/Ion Channel 相关产品(2265)

  • GC20029 structure
    GC20029 L(-)-Borneol
    CAS: 464-45-9
    纯度: >98.00%

    A bicyclic monoterpene

  • GC20062 structure
    GC20062trans-3'-Hydroxycotinine
    CAS: 34834-67-8
    纯度: >98.00%

    A metabolite of nicotine

  • GC20107 structure
    GC20107Fendiline hydrochloride
    CAS: 13636-18-5
    纯度: >98.00%

    An L-type calcium channel blocker

  • GC20108 structure
    GC20108Sevoflurane
    CAS: 28523-86-6
    纯度: >99.00%

    A halogenated ether with anesthetic properties

  • GC25134 structure
    GC25134Benzocaine hydrochloride
    CAS: 23239-88-5
    纯度: >99.00%

    Benzocaine hydrochloride (Ethyl 4-aminobenzoate, Ethyl p-aminobenzoate) is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.

  • GC25174 structure
    GC25174Brucine sulfate heptahydrate
    CAS: 60583-39-3

    Brucine is an alkaloid that acts as an antagonist at glycine receptors and paralyzes inhibitory neurons.

  • GC25345 structure
    GC25345Deudextromethorphan (AVP-786)
    CAS: 1079043-55-2

    Deudextromethorphan (AVP-786) is an active N-methyl-D-aspartate (NMDA) receptor antagonist.

  • GC25386 structure
    GC25386Ethacrynate Sodium
    CAS: 6500-81-8

    Ethacrynate Sodium (ethacrynic acid sodium) is the sodium salt form of ethacrynic acid, which inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules.

  • GC25405 structure
    GC25405Evodine
    CAS: 6989-38-4

    Evodine, a natural product extracted from Evodiae fructus (EF), is a biomarker for quality assessment of EF in the Chinese Pharmacopoeia. Evodine is a potent P-gp inhibitor.

  • GC25531 structure
    GC25531Isonipecotic acid
    CAS: 498-94-2

    Isonipecotic acid (4-Piperidinecarboxylic acid, 4-Carboxypiperidine, Hexahydroisonicotinic acid) is a heterocyclic compound that mainly acts as a GABAA receptor partial agonist.

  • GC25558 structure
    GC25558Lanthanum(III) chloride heptahydrate
    CAS: 10025-84-0

    Lanthanum(III) chloride is the inorganic compound used in biochemical research to block the activity of divalent cation channels, mainly calcium channels.

  • GC25566 structure
    GC25566L-DAB HBR
    CAS: 73143-97-2

    L-DAB HBR (L-Dab Hydrobromide, L-2,4-Diaminobutyric acid hydrobromide) is an inhibitor of GABA (Gamma-aminobutyric acid) transaminase with IC50 of >500 μM

  • GC25812 structure
    GC25812Quinidine sulfate
    CAS: 6591-63-5

    Quinidine (Chinidin, Pitayine, β-quinine, (+)-quinidine) acts as a blocker of voltage-gated sodium channels, also an antimuscarinic and antimalarial.

  • GC25936 structure
    GC25936SLC13A5-IN-1
    CAS: 2227548-95-8

    SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5/NaCT). It completely blocks the uptake of 14 C-citrate and has the potential for the treatment of metabolic and/or cardiovascular diseases.

  • GC25991 structure
    GC25991Tetrathiomolybdate
    CAS: 16330-92-0
    纯度: >98.00% / >99.50%

    Tetrathiomolybdate (TM) is used in the clinic for the treatment of Wilson's disease by inducing dimerization of the metal-binding domain of the cellular copper efflux protein ATP7B (WLN4) through a unique sulfur-bridged Mo2S6O2 cluster.

  • GC26029 structure
    GC26029Valbenazine tosylate
    CAS: 1639208-54-0

    Valbenazine tosylate (NBI-98854) is the tosylate salt of valbenazine, a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no significant binding to VAMT1(Ki<10 μM).

  • GC26033 structure
    GC26033Veratrine
    CAS: 62-59-9

    Veratridine (Cevadine, Cevadin, Cevadene), a steroidal alkaloid found in plants of the lily family, is a voltage-gated sodium channel activator. Veratridine induces anxiogenic-like behaviors in rats.

  • GC26184 structure
    GC26184Kynurenic acid-d5
    CAS: 350820-13-2
    纯度: >98.00%

    Kynurenic acid-d 5 是 Kynurenic acid 的氘代物。

  • GC26338 structure
    GC26338α-Cypermethrin
    CAS: 67375-30-8
    纯度: >99.00%
  • GC30033 structure
    GC30033Sinapine thiocyanate
    CAS: 7431-77-8
    纯度: >99.00%

    Sinapine thiocyanate is the thiocyanate salt form of Sinapine, which shows favorable biological activities such as antioxidant and radio-protective activities.

  • GC30054 structure
    GC30054Dantrolene sodium hemiheptahydrate (Dantrolene sodium hydrate)
    CAS: 24868-20-0
    纯度: >98.00%

    Dantrolene sodium hemiheptahydrate (Dantrium) ia a skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber.

  • GC30055 structure
    GC30055Pinaverium bromide
    CAS: 53251-94-8
    纯度: >98.00%

    Pinaverium bromide (Icosapentaenoic acid) acts as a calcium channel blocker and is useful for functional gastrointestinal disorders.

  • GC30063 structure
    GC30063Eleclazine hydrochloride (GS 6615 hydrochloride)
    CAS: 1448754-43-5
    纯度: >99.50%

    Eleclazine hydrochloride (GS 6615 hydrochloride)是一种新型、具有高度选择性的心脏晚期钠电流抑制剂，IC 50 值<1μM。

  • GC30088 structure
    GC30088Fluxametamide
    CAS: 928783-29-3
    纯度: >98.50% / >98.00%

    Fluxametamide是一种GABA和谷氨酸门控氯离子通道的拮抗剂，对GABACls和GluCls的IC 50 值分别为1.95nM和225nM。