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Membrane Transporter/Ion Channel

Membrane Transporter/Ion Channel(跨膜转运)

研究方向

Membrane Transporter/Ion Channel 相关产品(2265)

  • GC14410 structure
    GC14410(±)-Epibatidine
    CAS: 148152-66-3

    An agonist of α4β2 subunit-containing nAChRs

  • GC14414 structure
    GC14414CIQ
    CAS: 486427-17-2
    纯度: >98.00%

    A subunit-selective NMDA receptor potentiator

  • GC14442 structure
    GC14442TCS 46b
    CAS: 302799-86-6

    NR1A/NR2B NMDA receptor antagonist,orally active

  • GC14453 structure
    GC14453cis-ACBD
    CAS: 73550-55-7

    An NMDA receptor agonist

  • GC14470 structure
    GC14470Arcaine sulfate
    CAS: 14923-17-2
    纯度: >95.00%

    An NMDA receptor antagonist

  • GC14477 structure
    GC14477CI 966 hydrochloride
    CAS: 110283-66-4
    纯度: >99.00%

    GABA transporter GAT-1 inhibitor

  • GC14480 structure
    GC14480CNQX disodium salt
    CAS: 479347-85-8
    纯度: >98.00%

    A non-NMDA glutamate receptor antagonist

  • GC14481 structure
    GC14481A 887826
    CAS: 1266212-81-0

    A 887826 是一种有效的、选择性的、口服生物利用度和电压依赖性 Na(v)1.8 钠通道阻滞剂，IC50 为 11 nM。

  • GC14484 structure
    GC14484(-)-Xestospongin C
    CAS: 88903-69-9
    纯度: >90.00%

    A membrane-permeable antagonist of the inositol-1,4,5-triphosphate receptor

  • GC14487 structure
    GC14487Ranolazine
    CAS: 95635-55-5
    纯度: >99.00%

    Ranolazine (CVT 303) 是一种抗心绞痛药物，通过抑制内向钠电流（INa 和 IKr，IC50 值分别为 6 μM 和 12 μM）的晚期而不影响心率或血压 (BP) 来实现其效果。

  • GC14492 structure
    GC14492PF 4778574
    CAS: 1219633-99-4

    PF 4778574 是 AMPA 受体的正向变构调节剂，在不同细胞中的 EC50 为 45 至 919 nM。

  • GC14495 structure
    GC14495CX 546
    CAS: 215923-54-9
    纯度: >99.00%

    CX 546是一种强效的3-羟基-5-甲基-4-异唑丙酸（AMPA）受体激活剂，EC 50 值为93.2μM。

  • GC14515 structure
    GC14515Azimilide
    CAS: 149908-53-2

    A class III antiarrhythmic agent

  • GC14533 structure
    GC14533Kynurenic acid
    CAS: 492-27-3
    纯度: >99.00% / >98.00%

    Kynurenic acid 是一种内源性色氨酸代谢物，是一种针对 NMDA、谷氨酸、α7 烟碱乙酰胆碱受体的广谱拮抗剂。

  • GC14537 structure
    GC14537AMTB hydrochloride
    CAS: 926023-82-7

    A TRPM8 antagonist

  • GC14547 structure
    GC14547Quinolinic acid
    CAS: 89-00-9
    纯度: >99.00%

    An excitotoxic agonist at NMDA receptors

  • GC14563 structure
    GC14563Ketanserin
    CAS: 74050-98-9
    纯度: >99.00% / >97.00%

    A potent 5-HT 2 receptor antagonist

  • GC14579 structure
    GC14579NPEC-caged-(S)-AMPA
    CAS: 1257323-84-4

    AMPA receptor agonist

  • GC14598 structure
    GC145985,7-Dichlorokynurenic acid sodium salt
    CAS: 1184986-70-6

    An NMDA receptor antagonist

  • GC14635 structure
    GC14635RQ-00203078
    CAS: 1254205-52-1
    纯度: >99.00%

    A TRPM8 antagonist

  • GC14641 structure
    GC14641SKF 96365 hydrochloride
    CAS: 130495-35-1
    纯度: >99.50%

    SKF 96365 hydrochloride是一种具有口服活性的TRP通道/钙库操控性钙内流（SOCE）抑制剂，可阻断TRPC通道、电压门控钙通道及多种钾通道，并抑制STIM1介导的钙信号。

  • GC14642 structure
    GC146427ACC2
    CAS: 1472624-85-3
    纯度: >98.00%

    An MCT1 and MPC inhibitor

  • GC14646 structure
    GC14646RuBi-4AP
    CAS: 851956-02-0

    voltage-dependent K+ channel blocker

  • GC14649 structure
    GC14649Pyr3
    CAS: 1160514-60-2
    纯度: >99.50%

    Pyr3是瞬时受体电位经典通道3（TRPC3）的一种强效、选择性抑制剂，对TRPC3介导的钙离子内流的IC 50 为700nM。