Neuroscience
Neuroscience(神经科学)
Neuroscience
Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more
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Neuroscience 相关产品(3932)
- GC11960PramipexoleCAS: 104632-26-0纯度: >99.50%
Pramipexole 是一种选择性和血脑屏障 (BBB) 渗透性多巴胺 D2 型受体激动剂，对 D2 型受体、D2、D3 和 D4 受体的 Kis 分别为 2.2 nM、3.9 nM、0.5 nM 和 1.3 nM。
- GC11984Isamoltane hemifumarateCAS: 874882-92-5
Isamoltane hemifumarate 是 5-HT1B 受体的选择性拮抗剂，抑制 [125I]ICYP 与大鼠脑膜中 5-HT1B 识别位点的结合，IC50 为 39 nM。
- GC12198IEM 1754 dihydrobroMideCAS: 162831-31-4
IEM 1754 dihydrobroMide 是一种双阳离子金刚烷衍生物，是天然离子型谷氨酸受体开放通道的有效阻断剂，包括昆虫肌肉中的 quisqualate 敏感受体、培养的大鼠皮质神经元中的 NMDAR 和新鲜分离的海马细胞中的 AMPAR。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC11853 | Tenidap | 120210-48-2 | ≥98.00% | |
A COX-1 selective NSAID | ||||
| GC11901 | Nefiracetam | 77191-36-7 | >99.00% | |
An Analytical Reference Standard | ||||
| GC11959 | Naratriptan | 143388-64-1 | >98.00% | |
A potent 5-HT 1B and 5-HT 1D receptor agonist | ||||
| GC11960 | Pramipexole | 104632-26-0 | >99.50% | |
Pramipexole 是一种选择性和血脑屏障 (BBB) 渗透性多巴胺 D2 型受体激动剂，对 D2 型受体、D2、D3 和 D4 受体的 Kis 分别为 2.2 nM、3.9 nM、0.5 nM 和 1.3 nM。 | ||||
| GC11965 | (±)-Huperzine A | 120786-18-7 | >98.00% | |
A neuroprotective AChE inhibitor | ||||
| GC11984 | Isamoltane hemifumarate | 874882-92-5 | - | |
Isamoltane hemifumarate 是 5-HT1B 受体的选择性拮抗剂，抑制 [125I]ICYP 与大鼠脑膜中 5-HT1B 识别位点的结合，IC50 为 39 nM。 | ||||
| GC12039 | Cyclizine 2HCl | 5897-18-7 | - | |
Histamine H1 receptor antagonist | ||||
| GC12055 | Milnacipran HCl | 101152-94-7 | >99.50% | |
A serotonin and norepinephrine reuptake inhibitor | ||||
| GC12061 | Tripelennamine HCl | 154-69-8 | >99.50% | |
Tripelennamine HCl 是一种乙二胺衍生物，是一种有效的组胺 H1 受体拮抗剂。 | ||||
| GC12091 | SB742457 | 607742-69-8 | >98.00% | |
A 5-HT 6 receptor antagonist | ||||
| GC12096 | Semagacestat (LY450139) | 425386-60-3 | >99.50% | |
A pan γ-secretase inhibitor | ||||
| GC12156 | DuP 697 | 88149-94-4 | - | |
A selective COX-2 inhibitor | ||||
| GC12198 | IEM 1754 dihydrobroMide | 162831-31-4 | - | |
IEM 1754 dihydrobroMide 是一种双阳离子金刚烷衍生物，是天然离子型谷氨酸受体开放通道的有效阻断剂，包括昆虫肌肉中的 quisqualate 敏感受体、培养的大鼠皮质神经元中的 NMDAR 和新鲜分离的海马细胞中的 AMPAR。 | ||||
| GC12241 | NS 398 | 123653-11-2 | >98.50% | |
A selective COX2 inhibitor | ||||
| GC12276 | CGS 12066B dimaleate | 109028-10-6 | >98.00% | |
A 5-HT 1B receptor agonist | ||||
| GC12365 | Ranitidine hydrochloride | 66357-59-3 | >98.00% | |
A histamine H 2 receptor antagonist | ||||
| GC12398 | Granisetron | 109889-09-0 | - | |
Granisetron (BRL 43694) 是一种血清素 5-HT3 受体拮抗剂，用作止吐剂，用于治疗化疗后的恶心和呕吐。 | ||||
| GC12427 | 8-Hydroxy-PIPAT oxalate | 159651-91-9 | - | |
5-HT1A receptor agonist | ||||
| GC12444 | Clemizole | 442-52-4 | - | |
An antihistamine and TRPC5 channel blocker | ||||
| GC12453 | Succinylcholine Chloride Dihydrate | 6101-15-1 | - | |
An agonist of muscle-type nAChRs | ||||
| GC12495 | Olanzapine | 132539-06-1 | >99.00% / >98.00% / >99.50% | |
Olanzapine是一种单胺拮抗剂。 | ||||
| GC12541 | Bilobalide | 33570-04-6 | >98.00% | |
A neuroprotective natural product | ||||
| GC12549 | Mizolastine | 108612-45-9 | >98.00% | |
A histamine H 1 receptor antagonist | ||||
| GC12554 | Tiotropium Bromide | 136310-93-5 | >99.50% | |
A muscarinic receptor antagonist | ||||