GlpBio

Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

研究方向

Neuroscience 相关产品(3932)

  • GC10769 structure
    GC10769SB269970 HCl
    CAS: 261901-57-9
    纯度: >98.50% / >98.00%

    SB269970 HCl是一种强效且选择性的5-HT 7 受体拮抗剂，具有高亲和力 (pK i = 8.9)。

  • GC10772 structure
    GC10772Flumazenil
    CAS: 78755-81-4
    纯度: >99.50% / >98.00%

    A GABA A receptor antagonist and partial agonist

  • GC10799 structure
    GC10799Iloperidone hydrochloride
    CAS: 1299470-39-5

    An atypical antipsychotic

  • GC10806 structure
    GC10806Histamine 2HCl
    CAS: 56-92-8
    纯度: >98.00%

    A biogenic amine

  • GC10822 structure
    GC10822Clozapine N-oxide (CNO)
    CAS: 34233-69-7
    纯度: >98.00%

    Clozapine N-oxide（CNO）是一种强效的多巴胺拮抗剂，也是一种选择性肌动蛋白M4受体（EC50=11 nM）激动剂。

  • GC10848 structure
    GC10848BMY 7378
    CAS: 21102-95-4

    BMY 7378是一种α 1D -肾上腺素能受体（α 1D -AR）的选择性拮抗剂，pk i 值为8.89，也是血清素1A受体（5-HT 1A R）的混合激动剂和拮抗剂。

  • GC10863 structure
    GC10863Otilonium Bromide
    CAS: 26095-59-0
    纯度: >99.00%

    An L- and T-type calcium channel inhibitor and mAChR antagonist

  • GC10876 structure
    GC10876Vilazodone Hydrochloride
    CAS: 163521-08-2
    纯度: >98.00%

    An SSRI and a partial agonist of 5-HT 1A

  • GC10911 structure
    GC10911Venlafaxine hydrochloride
    CAS: 99300-78-4
    纯度: >99.50%

    Venlafaxine hydrochloride是一种具有口服活性的5-羟色胺和去甲肾上腺素再摄取抑制剂 （SNRIs; Serotonin-norepinephrine reuptake inhibitors），对配体与人NE和5-HT转运蛋白结合的Ki值分别为2480nM和82nM。

  • GC10945 structure
    GC10945Tandospirone
    CAS: 87760-53-0
    纯度: >99.00%

    Tandospirone (SM-3997) 是一种有效的选择性 5-HT1A 受体部分激动剂，Ki 为 27 nM。

  • GC10948 structure
    GC10948Varenicline Tartrate
    CAS: 375815-87-5
    纯度: >98.00%

    Varenicline Tartrate是一种选择性α7和α4β2烟碱型乙酰胆碱受体（nAChR）激动剂，对α4β2 nAChR的IC 50 值为250nM。

  • GC10966 structure
    GC10966Fexofenadine HCl
    CAS: 153439-40-8
    纯度: >99.50%

    Fexofenadine HCl是一种具有口服活性和非镇静作用的组胺H1受体拮抗剂。

  • GC10972 structure
    GC10972Gallamine Triethiodide
    CAS: 65-29-2
    纯度: >98.00%

    An allosteric modulator of muscarinic acetylcholine receptors

  • GC10973 structure
    GC10973SC 236
    CAS: 170569-86-5
    纯度: >99.00% / >99.50%

    A potent, selective COX-2 inhibitor

  • GC10974 structure
    GC10974AWD 131-138
    CAS: 188116-07-6
    纯度: >99.00%

    A partial agonist of the GABA A receptor

  • GC10985 structure
    GC10985MDL 72832 hydrochloride
    CAS: 113777-40-5

    ligand for 5-HT1A receptor, potent and selective

  • GC11009 structure
    GC11009Cetirizine DiHCl
    CAS: 83881-52-1
    纯度: >99.00%

    A selective histamine H 1 receptor antagonist

  • GC11020 structure
    GC11020Ziprasidone
    CAS: 146939-27-7
    纯度: >98.00%

    齐拉西酮 (CP-88059) 是一种口服活性抗精神病药，是一种 5-HT 和多巴胺受体拮抗剂的组合。

  • GC11028 structure
    GC11028Dopamine HCl
    CAS: 62-31-7
    纯度: >99.50% / >98.00% / >98.50%

    An endogenous catecholamine

  • GC11033 structure
    GC11033Rupatadine Fumarate
    CAS: 182349-12-8
    纯度: >99.50%

    A histamine H 1 and PAF receptor antagonist

  • GC11035 structure
    GC11035Hyoscyamine
    CAS: 101-31-5
    纯度: >98.00%

    A muscarinic receptor antagonist

  • GC11058 structure
    GC11058Scrambled 10Panx
    CAS: 1315378-72-3

    Panx-1 mimetic inhibitory peptide, blocks pannexin-1 gap junctions

  • GC11096 structure
    GC11096Mefenamic Acid
    CAS: 61-68-7
    纯度: >99.50%

    A NSAID and COX-2 inhibitor

  • GC11166 structure
    GC11166Alosetron Hydrochloride
    CAS: 122852-69-1
    纯度: >99.50%

    A 5-HT 3 receptor antagonist