Neuroscience
Neuroscience(神经科学)
Neuroscience
Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more
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Neuroscience 相关产品(3932)
- GC11186BrexpiprazoleCAS: 913611-97-9纯度: >97.00%
Brexpiprazole是一种口服非典型抗精神病药物,是5-HT1A(K i =0.12nM)和dopamine D2L(K i =0.3nM)受体的强效部分激动剂,以及5-HT2A受体(K i =0.47nM)的拮抗剂。
- GC11210Vecuronium BromideCAS: 50700-72-6纯度: >98.00% / >99.50%
Vecuronium Bromide是一种非去极化神经肌肉阻断剂,特异性地作用于肌肉型乙酰胆碱受体,IC 50 为1-2nM。
- GC11219(R)-(+)-TolterodineCAS: 124937-51-5纯度: >99.50%
(R)-(+)-Tolterodine(PNU-200583) 是一种有效的毒蕈碱受体拮抗剂,在体内对膀胱的选择性优于唾液腺。
- GC11382Pitolisant hydrochlorideCAS: 903576-44-3纯度: >99.50%
A histamine H 3 receptor antagonist and inverse agonist
- GC11506Haloperidol hydrochlorideCAS: 1511-16-6
A typical antipsychotic and dopamine D 2 -like receptor antagonist
- GC11643PNU-120596CAS: 501925-31-1纯度: >99.50% / >98.00%
PNU-120596是α7神经元烟碱乙酰胆碱受体(α7nAChR)的正变构调节剂,EC 50 值为216nM。
- GC11651Ondansetron hydrochloride dihydrateCAS: 103639-04-9纯度: >99.00%
An Analytical Reference Material
- GC11831Umeclidinium bromideCAS: 869113-09-7纯度: >98.00%
A muscarinic acetylcholine receptor antagonist
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC11182 | LY404039 | 635318-11-5 | >98.00% | |
An agonist of mGluR2 and mGluR3 | ||||
| GC11186 | Brexpiprazole | 913611-97-9 | >97.00% | |
Brexpiprazole是一种口服非典型抗精神病药物,是5-HT1A(K i =0.12nM)和dopamine D2L(K i =0.3nM)受体的强效部分激动剂,以及5-HT2A受体(K i =0.47nM)的拮抗剂。 | ||||
| GC11210 | Vecuronium Bromide | 50700-72-6 | >98.00% / >99.50% | |
Vecuronium Bromide是一种非去极化神经肌肉阻断剂,特异性地作用于肌肉型乙酰胆碱受体,IC 50 为1-2nM。 | ||||
| GC11219 | (R)-(+)-Tolterodine | 124937-51-5 | >99.50% | |
(R)-(+)-Tolterodine(PNU-200583) 是一种有效的毒蕈碱受体拮抗剂,在体内对膀胱的选择性优于唾液腺。 | ||||
| GC11382 | Pitolisant hydrochloride | 903576-44-3 | >99.50% | |
A histamine H 3 receptor antagonist and inverse agonist | ||||
| GC11384 | BTS 54-505 hydrochloride | 84484-78-6 | - | |
Potent SNRI,sibutramine metabolite | ||||
| GC11495 | Lofepramine | 23047-25-8 | >99.50% | |
A tricyclic antidepressant | ||||
| GC11506 | Haloperidol hydrochloride | 1511-16-6 | - | |
A typical antipsychotic and dopamine D 2 -like receptor antagonist | ||||
| GC11517 | SEA0400 | 223104-29-8 | >98.00% | |
A selective inhibitor of the Na + /Ca 2+ exchanger | ||||
| GC11521 | Ziprasidone HCl | 122883-93-6 | - | |
An atypical antipsychotic | ||||
| GC11570 | Desvenlafaxine | 93413-62-8 | - | |
An active metabolite of venlafaxine | ||||
| GC11617 | Pristimerin | 1258-84-0 | >99.50% | |
Potent, selective inhibitor of monoacylglycerol lipase | ||||
| GC11643 | PNU-120596 | 501925-31-1 | >99.50% / >98.00% | |
PNU-120596是α7神经元烟碱乙酰胆碱受体(α7nAChR)的正变构调节剂,EC 50 值为216nM。 | ||||
| GC11651 | Ondansetron hydrochloride dihydrate | 103639-04-9 | >99.00% | |
An Analytical Reference Material | ||||
| GC11709 | Fluoxetine HCl | 56296-78-7 | >99.50% | |
An Analytical Reference Material | ||||
| GC11714 | Prucalopride | 179474-81-8 | >99.50% | |
A selective 5-HT 4 receptor agonist | ||||
| GC11729 | RS 127445 | 199864-87-4 | - | |
RS 127445是一种具有口服活性的高选择性5-羟色胺受体2B(5-HT 2B )受体拮抗剂,pK i 为9.5,对5-HT 2B 的选择性是对5-HT 2A 、5-HT 2C 等其他相关受体的1000倍以上。 | ||||
| GC11743 | MF63 | 892549-43-8 | >99.00% | |
A potent, selective, and orally active mPGES-1 inhibitor | ||||
| GC11762 | Meloxicam (Mobic) | 71125-38-7 | >99.50% | |
A selective COX-2 inhibitor | ||||
| GC11773 | Pancuronium dibromide | 15500-66-0 | >99.00% | |
Pancuronium dibromide 是一种双季铵盐类固醇,是一种神经肌肉松弛剂。 | ||||
| GC11786 | Acetylcysteine | 616-91-1 | >99.00% | |
乙酰半胱氨酸是半胱氨酸的 N-乙酰基衍生物。 | ||||
| GC11824 | Asenapine | 65576-45-6 | >98.50% | |
An atypical antipsychotic | ||||
| GC11831 | Umeclidinium bromide | 869113-09-7 | >98.00% | |
A muscarinic acetylcholine receptor antagonist | ||||
| GC11842 | A-740003 | 861393-28-4 | >98.00% | |
A-740003是一种具有口服活性的P2X7受体拮抗剂(IC 50 =40nM)。 | ||||
