• 0
    My Cart

    Click Here to Find How Many Items You Have Added:)

qq在线咨询
Home >> Signaling Pathways >> Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. 产品名称 Information
  2. GC16139 (R,S)-Anatabine (tartrate)

    (±)-Anatabine

     A minor tobacco alkaloid
  3. GC52185 (R,S)-Anatabine-d4

    RAC-盐酸安那他品-D4

     An internal standard for the quantification of (R,S)-anatabine
  4. GC63452 (Rac)-5-Hydroxymethyl Tolterodine

    苯甲醇,3-[3-[双(1-甲基乙基)氨基]-1-苯基丙基]-4-羟基-,(Rac)-Desfesoterodine; (Rac)-PNU-200577

     (Rac)-5-Hydroxymethyl Tolterodine ((Rac)-Desfesoterodine) 是 Tolterodine 的一种活性代谢物，是一种 mAChR 拮抗剂 (M1、M2、M3、M4 和 M5 受体的 Ki 值分别为 2.3 nM、2 nM、2.5 nM、2.8 nM 和 2.9 nM)。(Rac)-5-Hydroxymethyl Tolterodine 可用于膀胱过度活动症研究。
  5. GC71582 (Rac)-5-Hydroxymethyl Tolterodine hydrochloride (Rac)-5-Hydroxymethyl Tolterodine hydrochloride是托特罗定的活性代谢产物，是mAChR拮抗剂。
  6. GC63511 (Rac)-CP-601927 hydrochloride (Rac)-CP-601927 hydrochloride 是 CP-601927 的外消旋物。CP-601927 是一种 nAChR 激动剂，对 α4β2 和 α3β4 nAChR 的 Ki 值分别为 1.2 nM 和 102 nM。
  7. GC61446 (Rac)-Lanicemine

    (Rac)-拉尼西明; (Rac)-AZD6765

     (Rac)-Lanicemine((Rac)-AZD6765)是Lanicemine的外消旋体。Lanicemine(AZD6765)是一种低捕获的NMDA受体拮抗剂，Ki为0.56-2.1 μM。CHO和爪蟾卵母细胞中，IC50分别为4-7μM和6.4μM。具有抗抑郁作用。
  8. GC63632 (Rac)-Lorcaserin

    8-氯-2,3,4,5-四氢-1-甲基-1H-3-苯并氮杂卓

     (Rac)-Lorcaserin ((Rac)-APD356 free base) 是一种减肥药和 5-HT2C 受体激动剂。
  9. GC60413 (Rac)-NMDAR antagonist 1 (Rac)-NMDARantagonist1是NMDARantagonist1的消旋体。NMDARantagonist1是一种有效且口服生物可利用的，NR2B选择性的NMDAR拮抗剂。
  10. GC62745 (Rac)-PF-06256142 (Rac)-PF-06256142 是 PF-06256142 的较弱的对映体。(Rac)-PF-06256142 是 D1 受体 (D1 receptor) 的激动剂，其 EC50 值为 107 nM。(Rac)-PF-06256142 可用于精神分裂症和帕金森病的研究。
  11. GC71283 (Rac)-Rotigotine (Rac)-Rotigotine N-0437是罗替戈汀的外消旋物。
  12. GC60004 (rel)-Tranylcypromine D5 hydrochloride

    反式-2-(苯基-D5)环丙胺盐酸盐,SKF 385-d5 hydrochloride

     Tranylcypromine-d5 (SKF 385-d5) hydrochloride 是氘标记的 (rel)-Tranylcypromine hydrochloride。
  13. GC10349 (RS)-(±)-Sulpiride

    舒必利

     An atypical antipsychotic
  14. GC16542 (RS)-3,4-DCPG antagonist of AMPA receptors and agonist of mGluR8
  15. GC12985 (RS)-3-Hydroxyphenylglycine

    3-羟基苯甘氨酸

     PI-linked metabotropic glutamate receptors agonist
  16. GC13288 (RS)-4-Carboxy-3-hydroxyphenylglycine

    (RS)-4-羧基-3-羟基苯甘氨酸

     broad spectrum EAA agonist/antagonist
  17. GC13773 (RS)-4-Carboxyphenylglycine broad spectrum EAA ligand
  18. GC62746 (RS)-AMPA monohydrate

    (±)-AMPA monohydrate

     (RS)-AMPA ((±)-AMPA) monohydrate 是一种谷氨酸类似物，是一种有效的选择性兴奋性神经递质 L-谷氨酸 (L-glutamic acid) 激动剂。(RS)-AMPA monohydrate 不会干扰海藻酸或 NMDA 受体的结合位点。
  19. GC11771 (RS)-APICA (RS)-APICA 是一种选择性 II 组代谢型谷氨酸受体 (mGluR II) 拮抗剂。
  20. GC12279 (RS)-MCPG

    alpha-MCPG

     (RS)-MCPG (alpha-MCPG) 是一种竞争性和选择性的 I 组/II 组代谢型谷氨酸受体 (mGluR) 拮抗剂。
  21. GC11997 (RS)-MCPG disodium salt group I/group II metabotropic glutamate receptor antagonist
  22. GC11433 (RS)-PPG

    4-磷酰基苯甘氨酸

     (RS)-PPG 是 III 组 mGluR 的有效选择性激动剂。
  23. GC10704 (S)-(+)-α-Methylhistamine dihydrobromide H3 histamine receptor agonist
  24. GC41727 (S)-(+)-3-Quinuclidinol

    (S)-(+)-3-喹宁醇

    (S)-(+)-Quinuclidinol is a precursor in the synthesis of solifenacin.
  25. GC46346 (S)-(+)-Clopidogrel-d3 (sulfate) A neuropeptide with diverse biological activities
  26. GC14479 (S)-(+)-Dimethindene maleate (S)-(+)-Dimethindene maleate 是一种对映异构体，是一种有效的 M2 选择性毒蕈碱受体拮抗剂 (pA2 =7.86/7.74; pKi =7.78)。
  27. GC13114 (S)-(+)-Ibuprofen

    (S)-(+)-布洛芬; (S)-Ibuprofen

     An active enantiomer of ibuprofen
  28. GC64804 (S)-(+)-Ibuprofen D3

    (S)-布洛芬-D3,(S)-Ibuprofen D3

     (S)-(+)-Ibuprofen D3 ((S)-Ibuprofen D3) 是(S)-(+)-Ibuprofen 的氘代物。(S)-(+)-Ibuprofen 是 Ibuprofen 的 S 型异构体，可抑制 COX-1 和 COX-2 活性，IC50 为 2.1 μM 和 1.6 μM。(S)-(+)-Ibuprofen 具有止痛，抗炎和解热作用。
  29. GC41731 (S)-(+)-Linoleyl-2'-Hydroxy-1'-Propylamide A homolog of LOEA
  30. GC11889 (S)-(-)-5-Fluorowillardiine

    5-氟代尿嘧啶丙氨酸; (5S)-Fluorowillardiine; (S)-5-Fluorowillardiine

     (S)-(-)-5-Fluorowillardiine 是一种有效且特异性的 AMPAR 激动剂。
  31. GC34998 (S)-(-)-5-Fluorowillardiine hydrochloride

    (5S)-Fluorowillardiine hydrochloride; (S)-5-Fluorowillardiine hydrochloride

     (S)-(-)-5-Fluorowillardiine hydrochloride 是AMPAR高效选择性激动剂。
  32. GC64735 (S)-(-)-Levamisole

    左旋咪唑碱; Levamisole; L-Tetramisole; Levamisol

     (S)-(-)-Levamisole (Levamisole)，一种驱虫剂，具有免疫调节特性的。(S)-(-)-Levamisole 作为 α3β2 (EC50=300 μM) 和 α3β4 (EC50=100 μM) 的正变构调节剂 (PAM) ) nAChRs 的亚型。具有口服活性。
  33. GC14639 (S)-3,4-DCPG

    (S)-3,4-二甲酸苯基甘氨酸,(S)-3,4-Dicarboxyphenylglycine

     A selective agonist of mGluR8
  34. GC16858 (S)-3,5-DHPG

    (S)-3,5-二羟基苯基甘氨酸

     A selective agonist of group I mGluRs
  35. GC11536 (S)-3-Carboxy-4-hydroxyphenylglycine group I metabotropic glutamate receptor antagonist and group II mGlu agonist
  36. GC16234 (S)-3-Hydroxyphenylglycine

    (S)-3-羟基苯甘氨酸

     group I metabotropic glutamate receptors agonist
  37. GC45964 (S)-3-N-Cbz-amino-succinimide An anticonvulsant
  38. GC12012 (S)-4-Carboxy-3-hydroxyphenylglycine group I mGlu1a/1a receptor antagonist and mGluR2 agonist
  39. GC14176 (S)-4-Carboxyphenylglycine group I metabotropic glutamate receptor antagonist
  40. GC40595 (S)-AM1241

    (-)AM1241

     A CB2 receptor agonist
  41. GC63655 (S)-Amisulpride

    (S)-氨磺必利; Esamisulpride; SEP-4199

     (S)-Amisulpride (Esamisulpride) 是一种有效的多巴胺 D2/D3 受体拮抗剂。(S)-Amisulpride 是 5-HT7 受体的拮抗剂，KI 值为 900 nM。(S)-Amisulpride 具有抗精神和抗抑郁作用。
  42. GC73666 (S)-Bexicaserin (S)-Bexicaserin（化合物2）是一种5-HT2C受体激动剂，具有研究肥胖和精神相关疾病的潜力。
  43. GC46352 (S)-DO271 An inactive control for DO264
  44. GC18022 (S)-Flurbiprofen

    (S)-氟比洛芬,Esflurbiprofen

     The COX-active enantiomer of flurbiprofen
  45. GC10739 (S)-HexylHIBO Group I mGlu receptor antagonist
  46. GC15977 (S)-Ketoprofen

    (S)-(+)-酮洛芬; (S)-Ketoprofen; Dexketoprofen

     A potent inhibitor of COX-1 and COX-2
  47. GC41389 (S)-Ketorolac

    (1S)-5-苯基-2,3-二氢-1H-吡啶-1-羧酸,(-)-Ketorolac

     A non-selective COX inhibitor
  48. GC41738 (S)-KT109 An isomer of KT109
  49. GC40145 (S)-Laudanosine

    (+)-Laudanosine, L-Laudanosine, L-(+)-Laudanosine, NSC 35045

     The (S) enantiomer of laudanosine
  50. GC16349 (S)-MCPG

    (+)-MCPG

     An mGluR antagonist
  51. GC67989 (S)-Mirtazapine

    (S)-Org3770; (S)-6-Azamianserin

     (S)-Mirtazapine ((S)-Org3770) 是 Mirtazapine 的 S(+)-对映异构体，在急性热伤害感受动物模型中具有促伤害感受的特性。(S)-Mirtazapine 是一种立体选择性 5-HT2 受体拮抗剂，在体内被 CYP2D6 和 CYP1A2 代谢。

Items 201 to 250 of 3961 total

per page
  2. 3
  3. 4
  4. 5
  5. 6
  6. 7

Set Descending Direction