Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC68410 (S)-Mirtazapine-d3

(S)-Org3770 D3; (S)-6-Azamianserin D3
(S)-Mirtazapine D3 ((S)-Org3770 D3) 是 (S)-Mirtazapine 氘代物。(S)-Mirtazapine 是 Mirtazapine 的 S(+)-对映异构体，在急性热伤害感受动物模型中具有促伤害感受的特性。(S)-Mirtazapine 是一种立体选择性 5-HT2 受体拮抗剂，在体内被 CYP2D6 和 CYP1A2 代谢。
GC14820 (S)-Naproxen

萘普生; (S)-Naproxen
An NSAID and COX inhibitor
GC49179 (S)-O-Desmethyl Naproxen

萘普生杂质A
A metabolite of (S)-naproxen
GC46355 (S)-Pramipexole-d5 (hydrochloride)

普拉克索杂质
An internal standard for the quantification of (S)-pramipexole
GC33686 (S)-Rasagiline (TVP1022)

(S)-雷沙吉兰; TVP1022; S-PAI
(S)-雷沙吉兰 (TVP1022) (TVP1022) 是雷沙吉兰相对无活性的 S-对映异构体形式。
GC35006 (S)-Rasagiline mesylate

(S)-雷沙吉兰甲磺酸; TVP1022 mesylate; S-PAI mesylate
(S)-Rasagiline (TVP1022) 甲磺酸盐是S-构型Rasagiline，对MAO-B的活性弱。
GC69941 (S)-Renzapride

(S)-BRL 24924
(S)-Renzapride ((S)-BRL 24924) 是 Renzapride 的异构体。Renzapride 是一种 5-HT4 受体激动剂，Ki 值为 115 nM。Renzapride 还是一种 5HT2b 和 5HT3 受体拮抗剂。Renzapride 可用于便秘型肠易激综合征（C-IBS）的研究。
GC72905 (S)-Setastine

(S)-EGIS-2062 free acid; (S)-EGYT-2062 free acid
(S)-SetastineS-EGIS-2062游离酸是一种非镇静、高效的H1受体介导反应拮抗剂。
GC15464 (S)-SNAP 5114 (S)-SNAP 5114 是一种选择性 GABA 转运抑制剂，对 hGAT-3 和 rGAT-2 的 IC50 值分别为 5 μM 和 21 μM。
GC60423 (S)-UFR2709 hydrochloride (S)-UFR2709(hydrochloride)是一种竞争性的nAChR拮抗剂，并显示出较强的亲和力，对α4β2nAChR的亲和力比对α7nAChR的高。(S)-UFR2709(hydrochloride)在偏好酒精的老鼠中减少焦虑，并且可以减少其酒精摄入和对酒精偏好。(S)-UFR2709(hydrochloride)是抗焦虑试剂，可用于研究尼古丁成瘾。
GC60424 (S)-Venlafaxine

文拉法辛S-异构体
(S)-Venlafaxine是Venlafaxine的S构型化合物。Venlafaxine是口服有效的5-羟色胺(5-HT)/去甲肾上腺素(NE)重摄取的双重抑制剂。Venlafaxine具有抗抑郁作用。
GC69979 (S)-VQW-765

(S)-AQW-051
(S)-VQW-765 ((S)-AQW-051) 是一种具有口服活性、选择性和有效性的 α7 烟碱 Ach 受体 (nAChR) 部分激动剂。(S)-VQW-765 在神经疾病相关的认知障碍中有潜在的应用，例如阿尔茨海默病或精神分裂症。
GC14805 (S)-WAY 100135 dihydrochloride A 5-HT_1A receptor antagonist
GC30212 (S)-Willardiine ((-)-Willardiine)

尿嘧啶基丙氨酸; (-)-Willardiine
(S)-Willardiine ((-)-Willardiine) 是一种有效的 AMPA/红藻氨酸受体激动剂，EC50 为 44.8 uM。
GC35011 (Z)-Thiothixene

替沃噻吨
(Z)-Thiothixene 是 serotonergic receptor 的拮抗剂，来自专利 US 20150141345 A1。
GC18596 (±)-2-propyl-4-Pentenoic Acid

2-丙基-4-五烯酸,2-Allylpentanoic Acid, 4-ene VPA
A metabolite of valproic acid
GC12927 (±)-Baclofen

巴氯芬
A GABA_B receptor agonist
GC11965 (±)-Huperzine A

(±)-石杉碱甲
A neuroprotective AChE inhibitor
GC19824 (±)-Pinocembrin

松属素,(±)-5,7-Dihydroxyflavanone; NSC 43318
A flavonoid with diverse biological activities
GC13786 (±)-Salsolinol (hydrochloride) A metabolite of ethanol that targets dopaminergic neurons
GC26151 (−)-Apomorphine (hydrochloride hydrate)

5,6,6aR,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol, monohydrochloride, hydrate
(-)-Apomorphine (hydrochloride hydrate)是一种强效的多巴胺受体激动剂，对D1-和D2类受体（D1、D2S、D2L、D3、D4、D5）都具有广泛作用。
GC49034 1(R)-(Trifluoromethyl)oleyl alcohol An oleic acid analog
GC46366 1,2,3,4-Tetrahydro-β-carboline

1,2,3,4-四氢-9H-吡啶[3,4-B]并吲哚
A serotonin reuptake inhibitor and metabolite of tryptamine
GC45698 1,2,3-Triheptanoyl-rac-glycerol

三庚酸甘油酯
A triacylglycerol
GC41774 1,2,3-Trimyristoyl-rac-glycerol

三肉豆蔻酸甘油酯
A triacylglycerol
GC46009 1,2,3-Trioctanoyl-rac-glycerol-13C3

三辛酸甘油酯-1,1,1-13
An internal standard for the quantification of 1,2,3-trioctanoyl glycerol-¹³C₃
GC18334 1,2-Dierucoyl-sn-glycero-3-PC

1,2-二芥酰-SN-甘油-3-磷酰胆碱; L-Dierucoyl lecithin; Dierucoyllecithin
A phospholipid
GC45304 1,3-Dipalmitoyl-rac-glycerol

1,3-双棕榈酸甘油酯
A diacylglycerol
GC42050 1-β-D-Glucosylsphingadienine (d18:2 (4E,8E))

Glucosylsphingadienine (d18:2 (4E,8E)), 1-β-D-Glucosylsphingadienine (plant), Glucosylsphingosine (plant)
A sphingolipid
GC42051 1-β-D-Glucosylsphingosine (d18:1)

Glucosyl-C18-Sphingosine, Glucosylsphingosine (d18:1), 1-β-D-Glucosylsphingosine (synthetic)
A lysolipid derivative of glucocerebroside
GC41751 1-(3,5-Dimethylphenyl)piperazine

1-(3,5-二甲基苯基)哌嗪
A heterocyclic building block
GC49346 1-(3-Chlorophenyl)biguanide (hydrochloride)

m-Chlorophenylbiguanide hydrochloride, meta-Chlorophenylbiguanide, m-CPBG, meta-CPBG
A 5-HT₃ receptor agonist
GC49294 1-(4-Chlorobenzhydryl)piperazine

1-(4-氯二苯甲基)哌嗪
An inactive metabolite of meclizine and chlorcyclizine
GC41761 1-(6-Methoxy-2-naphthyl)ethanol

DL-6-甲氧基-ALPHA-甲基-2-萘甲醇
A potential impurity found in commercial naproxen preparations
GC18009 1-Acetyl-4-methylpiperazine hydrochloride nAChR agonist
GC12863 1-BCP

Piperonylic acid piperidide
A positive allosteric modulator of AMPA receptors
GC49861 1-Carboxycyclohexaneacetic Acid

加巴喷丁杂质E
A potential impurity in commercial preparations of gabapentin
GC46050 1-Deoxysphingosine (m18:1(4E))

1-deoxySO, 4E-1-Deoxysphingosine (m18:1)
An atypical sphingolipid
GC26199 1-heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine

1-十七碳酰-甘油-3-磷酰胆碱
GC60447 1-Hydroxy-ibuprofen

1-羟基异丁基苯基-1'-甲基丙酸
1-hydroxy Ibuprofen 是非甾体类抗炎药 (NSAID) 和非选择性 COX 抑制剂布洛芬的代谢物。
GC19514 1-Methyl-L-tryptophan

相思子碱
An IDO inhibitor
GC38698 1-Naphthyl acetate

乙酸-1-萘酯
1-Naphthyl acetate is usually used in a rapid staining method for identification of macrophages. 1-Naphthyl acetate is a potent chromogenic substrate for the detection of erythrocyte acetylcholinesterase (AChE) activity.
GC49818 1-Octen-3-ol

1-辛烯-3-醇
A volatile organic compound
GC40910 1-Oleoyl-2-hydroxy-sn-glycero-3-PE

18:1 LPE, 18:1 Lyso-PE, 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine
A lysophospholipid
GC45979 1-Palmitoyl-2-Oleoyl-3-Arachidonoyl-rac-glycerol

1-Palmitin-2-Olein-3-Arachidonin, TG(16:0/18:1/20:4)
A triacylglycerol
GC49366 1-Salicylate Glucuronide

Salicyl Phenolic Glucuronide, Salicylic Acid Phenolic Glucuronide
A metabolite of salicylic acid and aspirin
GC49088 1-Stearoyl-2-Adrenoyl-sn-glycero-3-PE

1-Octadecanoyl-2-Docosatetraenoyl-sn-glycero-3-Phosphatidylethanolamine, 1-Octadecanoyl-2-Docosatetraenoyl-sn-glycero-3-Phosphoethanolamine, 1-Octadecanoyl-2-Docosatetraenoyl-sn-glycero-3-PE, PE(18:0/22:4), 1-Stearoyl-2-Docosatraenoyl-sn-glycero-3-PE
A phospholipid
GC42045 1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC

DHA-PC, 18:0/22:6 PC, PC(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)), 1-Stearoyl-2-Docosahexaenoyl-sn-glycero-3-Phosphatidylcholine, 1-Stearoyl-2-Docosahexaenoyl-sn-glycero-3-Phosphocholine
A phospholipid
GC40176 1-Stearoyl-rac-glycerol

单硬脂酸甘油酯
A monoacylglycerol
GC49820 10,11-dihydro-10,11-dihydroxy Carbamazepine

奥卡西平杂质
A metabolite of carbamazepine and oxcarbazepine