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Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

研究方向

Neuroscience 相关产品(3932)

  • GC52495 structure
    GC52495AF-353 (hydrochloride)
    CAS: 927887-18-1
    纯度: >98.00%

    A dual P2X 3 and P2X 2/3 receptor antagonist

  • GC52496 structure
    GC52496Sulfatide (bovine) (sodium salt)
    纯度: >95.00%

    A mixture of isolated bovine sulfatides

  • GC52497 structure
    GC52497Lactosylceramide (porcine RBC)
    纯度: >98.00%

    A sphingolipid

  • GC52498 structure
    GC52498NGB 2904 (hydrochloride)
    CAS: 189061-11-8
    纯度: >98.00%

    A selective D 3 antagonist

  • GC52500 structure
    GC52500Dynorphin A (trifluoroacetate salt)
    纯度: >95.00%

    Dynorphin A (trifluoroacetate salt)是一种内源性阿片肽，可激活孤儿受体XOR1-K + 通道，EC 50 值为45nM。

  • GC52502 structure
    GC52502Peptide YY (3-36) (trifluoroacetate salt)
    纯度: >95.00%

    A satiety hormone

  • GC52505 structure
    GC52505Ganglioside GT1b (bovine) (sodium salt)
    纯度: >98.00%

    A sphingolipid

  • GC52507 structure
    GC52507Orexin A amide (bovine, human, mouse, rat) (trifluoroacetate salt)
    纯度: >95.00%

    A hypothalamic neuropeptide

  • GC52514 structure
    GC52514Arachidonic Acid-d11 ethyl ester
    纯度: >99.00%

    An internal standard for the quantification of arachidonic acid ethyl ester

  • GC60000 structure
    GC60000(2S)-6-Prenylnaringenin
    CAS: 68236-13-5
    纯度: >99.50%

    A prenylated flavonoid with diverse biological activities

  • GC60004 structure
    GC60004(rel)-Tranylcypromine D5 hydrochloride
    CAS: 107077-98-5
    纯度: >98.00%

    Tranylcypromine-d5 (SKF 385-d5) hydrochloride 是氘标记的 (rel)-Tranylcypromine hydrochloride。

  • GC60017 structure
    GC600172'-O-Methylisoliquiritigenin
    CAS: 51828-10-5
    纯度: >98.00%

    2'-O-Methylisoliquiritigenin可从Arachis中分离得到，可上调5-HT、NE、DA和GABA信号通路，对NE通路影响不大。

  • GC60026 structure
    GC600265-AAM-2-CP
    CAS: 175424-74-5
    纯度: >98.00%

    5-AAM-2-CP是一种Acetamiprid的主要代谢产物。Acetamiprid是一种广泛使用的新烟碱类杀虫剂，是nAChR的激动剂。

  • GC60027 structure
    GC600275-AMAM-2-CP
    CAS: 864628-19-3
    纯度: >98.00%

    5-AMAM-2-CP是一种Acetamiprid的主要代谢产物。Acetamiprid是一种广泛使用的新烟碱类杀虫剂，是nAChR的激动剂。

  • GC60028 structure
    GC600285-HT1A modulator 2 hydrochloride
    CAS: 3880-76-0
    纯度: >98.00%

    5-HT1Amodulator2hydrochloride是8-OH-DPAT的一种衍生物，5-HT1Amodulator2hydrochloride是5-HT1A的调节剂，与5-HT1A结合的Ki值为53nM。

  • GC60037 structure
    GC60037A-3 hydrochloride
    CAS: 78957-85-4
    纯度: >99.50%

    A-3 hydrochloride, a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases, againsts cAMP-dependent protein kinase (PKA) (Ki=4.3 ?M), casein kinase II (CK2) (Ki=5.1 ?M) and myosin light chain kinase (MLCK) (Ki=7.4 ?M), also inhibits Protein Kinase C (PKC) and casein kinase I (CK1) with Ki values of 47 ?M and 80 ?M, respectively.

  • GC60049 structure
    GC60049Anisodamine hydrobromide
    CAS: 55449-49-5
    纯度: >98.00%

    Anisodamine (6-Hydroxyhyoscyamine) is a naturally occurring atropine derivative and exhibits anti-inflammatory activity. It also inhibits α1-adrenergic receptors and muscarinic acetylcholine receptors (mAChRs).

  • GC60072 structure
    GC60072Betahistine
    CAS: 5638-76-6
    纯度: >98.00%

    A histamine H 3 receptor antagonist and histamine H 1 receptor agonist

  • GC60075 structure
    GC60075BI99179
    CAS: 1291779-76-4
    纯度: >99.50%

    BI99179 是一种有效的选择性 I 型脂肪酸合成酶 (FAS) 抑制剂，IC50 为 79 nM。在大鼠中口服 BI 99179 表现出显着的外周和中央暴露。

  • GC60108 structure
    GC60108Chlorpyrifos
    CAS: 2921-88-2
    纯度: >99.50% / >99.00%

    毒死蜱作为一种广谱有机硫代磷酸酯类杀虫剂，其主要致毒机制是通过使神经接头处的乙酰胆碱酯酶失活。

  • GC60164 structure
    GC60164Fenitrothion
    CAS: 122-14-5

    Fenitrothion 是应用最广泛的有机磷农药之一，是一种抑制胆碱酯酶的杀虫剂/杀螨剂。Fenitrothion 作为一种广谱杀虫剂，广泛应用于棉田作物、蔬菜作物、水果作物和大田作物，尤其是水稻。Fenitrothion 导致硝基酚的积累。

  • GC60165 structure
    GC60165Ferulamide
    CAS: 61012-31-5

    Ferulamide是从PortulacaoleraceaL.中分离的具有抗胆碱酯酶活性的阿魏酸衍生物。

  • GC60167 structure
    GC60167Fipronil
    CAS: 120068-37-3
    纯度: >98.00%

    An insecticide

  • GC60211 structure
    GC60211JNJ-42226314
    CAS: 1252765-13-1
    纯度: >99.50%

    JNJ-42226314 是一种竞争性，高度选择性和可逆的非共价单酰甘油脂肪酶 MAGL 抑制剂。JNJ-42226314 可剂量依赖性增强主要的内源性大麻素 2-花生四烯酰甘油 (2-AG)，在神经性和炎性疼痛模型中表现出抗伤害作用。