Chromatin/Epigenetics
Chromatin/Epigenetics(染色质/表观遗传学)
Epigenetics
Epigenetics means above genetics. It determines how much and whether a gene is expressed without changing DNA sequences. Epigenetic regulations include, 1. DNA methylation: the addition of methyl group to DNA, converting cytosine to 5-methylcytosine, mostly at CpG sites; 2. Histone modifications: posttranslational modificationEpigeneticss of histone proteins including acetylation, methylation, ubiquitylation, phosphorylation and sumoylation; 3. miRNAs: non-coding microRNA downregulating gene expression; 4. Prions: infectious proteins viewed as epigenetic agents capable of inducing a phenotype without changing the genome.
- Bromodomain(50)
- Aurora Kinase(63)
- DNA Methyltransferase(35)
- HDAC(210)
- Histone Acetyltransferases(78)
- Histone Demethylases(110)
- Histone Methyltransferase(240)
- HIF(102)
- JAK(173)
- MBT Domains(1)
- PARP(122)
- Pim(32)
- Protein Ser/Thr Phosphatases(34)
- RNA Polymerase(7)
- Sirtuin(77)
- Sphingosine Kinase-2(1)
- Polycomb repressive complex(2)
- SUMOylation(3)
- PAD(21)
- Epigenetic Reader Domain(246)
- MicroRNA(24)
- Protein Arginine Deiminase(7)
- Chromodomain(1)
- Citrullination(20)
- DNA/RNA Demethylation(2)
- DNA/RNA Methylation(8)
- Histone Deacetylation(44)
- Histones/Histone Peptides(62)
- PHD Domains(1)
- Tandem Tudor & Tudor-like Domains(1)
- PRMT(2)
- Readers(1)
- Small Interfering RNA (siRNA)(1)
- METTL3(2)
- WDR5(1)
- TET Protein(2)
- HuR(1)
- SF3B1(1)
Chromatin/Epigenetics 相关产品(1617)
- GC48805Methapyrilene (hydrochloride)CAS: 135-23-9纯度: >98.00%
An H 1 receptor antagonist and non-genotoxic carcinogen
- GC48994Girard’s Reagent P-d5CAS: 1505505-87-2纯度: >99.00%
An internal standard for the quantification of Girard's reagent P
- GC49062Tiopronin-d3CAS: 1189700-74-0纯度: >99.00%
An internal standard for the quantification of tiopronin
- GC49190Roxadustat-d5CAS: 2043026-13-5纯度: >99.00%
An internal standard for the quantification of roxadustat
- GC49270Nicotinamide-d4CAS: 347841-88-7纯度: >99.00%
An internal standard for the quantification of nicotinamide
- GC49393all-trans-13,14-DihydroretinolCAS: 115797-14-3纯度: >95.00%
A metabolite of all-trans retinoic acid
- GC49412NSC 756093CAS: 1629908-92-4纯度: >98.00%
An inhibitor of the GBP1-Pim-1 protein-protein interaction
- GC49692Tofacitinib-d3 (citrate)纯度: >99.00%
An internal standard for the quantification of tofacitinib
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC48620 | BPKDi | 1201673-28-0 | >98.00% | |
A PKD inhibitor | ||||
| GC48775 | AES-350 | 847249-57-4 | >98.00% | |
An inhibitor of class I and class IIb HDACs | ||||
| GC48805 | Methapyrilene (hydrochloride) | 135-23-9 | >98.00% | |
An H 1 receptor antagonist and non-genotoxic carcinogen | ||||
| GC48967 | D-Homoserine lactone | 51744-82-2 | >95.00% | |
An enantiomer of L-homoserine lactone | ||||
| GC48971 | AZD 1152 (hydrochloride) | 722543-50-2 | >95.00% | |
A prodrug for a potent Aurora B inhibitor | ||||
| GC48980 | EPZ004777 (formate) | - | >98.00% | |
DOT1L 的有效抑制剂 | ||||
| GC48982 | CD532 | 1639009-81-6 | >98.00% | |
An inhibitor of Aurora A kinase activity and the Aurora A-N-Myc protein-protein interaction | ||||
| GC48986 | 9-hydroxy Stearic Acid | 3384-24-5 | >95.00% | |
A hydroxy fatty acid | ||||
| GC48994 | Girard’s Reagent P-d5 | 1505505-87-2 | >99.00% | |
An internal standard for the quantification of Girard's reagent P | ||||
| GC49029 | CAY17c | 2414373-11-6 | >98.00% | |
An inhibitor of BRD4 and class I and class IIb HDACs | ||||
| GC49062 | Tiopronin-d3 | 1189700-74-0 | >99.00% | |
An internal standard for the quantification of tiopronin | ||||
| GC49116 | Prohexadione | 88805-35-0 | >98.00% | |
A plant growth regulator | ||||
| GC49124 | EN219 | 380351-29-1 | >95.00% | |
An RNF114 recruiter | ||||
| GC49190 | Roxadustat-d5 | 2043026-13-5 | >99.00% | |
An internal standard for the quantification of roxadustat | ||||
| GC49270 | Nicotinamide-d4 | 347841-88-7 | >99.00% | |
An internal standard for the quantification of nicotinamide | ||||
| GC49393 | all-trans-13,14-Dihydroretinol | 115797-14-3 | >95.00% | |
A metabolite of all-trans retinoic acid | ||||
| GC49398 | GSK3368715 (hydrochloride) | 2227587-25-7 | >98.00% | |
An inhibitor of type I PRMTs | ||||
| GC49412 | NSC 756093 | 1629908-92-4 | >98.00% | |
An inhibitor of the GBP1-Pim-1 protein-protein interaction | ||||
| GC49692 | Tofacitinib-d3 (citrate) | - | >99.00% | |
An internal standard for the quantification of tofacitinib | ||||
| GC49693 | HDAC5 (human, recombinant) | - | >90.00% | |
Active, pure human recombinant enzyme | ||||
| GC49815 | Oleuropein aglycone | 31773-95-2 | >98.00% | |
A polyphenol with diverse biological activities | ||||
| GC50050 | Hesperadin hydrochloride | - | - | |
A multi-kinase inhibitor | ||||
| GC50066 | Atiprimod dihydrochloride | 130065-61-1 | - | |
JAK2 inhibitor | ||||
| GC50070 | I-BET 151 dihydrochloride | 1883545-47-8 | - | |
A BRD2, BRD3, and BRD4 inhibitor | ||||