Chromatin/Epigenetics
Chromatin/Epigenetics(染色质/表观遗传学)
Epigenetics
Epigenetics means above genetics. It determines how much and whether a gene is expressed without changing DNA sequences. Epigenetic regulations include, 1. DNA methylation: the addition of methyl group to DNA, converting cytosine to 5-methylcytosine, mostly at CpG sites; 2. Histone modifications: posttranslational modificationEpigeneticss of histone proteins including acetylation, methylation, ubiquitylation, phosphorylation and sumoylation; 3. miRNAs: non-coding microRNA downregulating gene expression; 4. Prions: infectious proteins viewed as epigenetic agents capable of inducing a phenotype without changing the genome.
- Bromodomain(50)
- Aurora Kinase(63)
- DNA Methyltransferase(35)
- HDAC(210)
- Histone Acetyltransferases(78)
- Histone Demethylases(110)
- Histone Methyltransferase(240)
- HIF(102)
- JAK(173)
- MBT Domains(1)
- PARP(122)
- Pim(32)
- Protein Ser/Thr Phosphatases(34)
- RNA Polymerase(7)
- Sirtuin(77)
- Sphingosine Kinase-2(1)
- Polycomb repressive complex(2)
- SUMOylation(3)
- PAD(21)
- Epigenetic Reader Domain(246)
- MicroRNA(24)
- Protein Arginine Deiminase(7)
- Chromodomain(1)
- Citrullination(20)
- DNA/RNA Demethylation(2)
- DNA/RNA Methylation(8)
- Histone Deacetylation(44)
- Histones/Histone Peptides(62)
- PHD Domains(1)
- Tandem Tudor & Tudor-like Domains(1)
- PRMT(2)
- Readers(1)
- Small Interfering RNA (siRNA)(1)
- METTL3(2)
- WDR5(1)
- TET Protein(2)
- HuR(1)
- SF3B1(1)
Chromatin/Epigenetics 相关产品(1617)
- GC46892ATRA-BA HybridCAS: 1037543-26-2纯度: >95.00%
A prodrug form of all-trans retinoic acid and butyric acid
- GC46935Bobcat 339CAS: 2280037-51-4纯度: >98.00%
Bobcat 339是一种具有良好选择性的新型胞嘧啶类TET酶抑制剂，对TET1和TET2的IC 50 值分别为33μM和73μM，但不抑制DNA甲基转移酶DNMT3a。
- GC47294Entacapone-d10CAS: 1185241-19-3纯度: >99.00%
An internal standard for the quantification of entacapone
- GC47432Histone H3 (69-89) amide (human, mouse, rat, bovine) (trifluoroacetate salt)纯度: >95.00%
A neuropeptide with diverse biological activities
- GC47439Hydralazine-d4 (hydrochloride)CAS: 2749234-32-8纯度: >99.00%
A neuropeptide with diverse biological activities
- GC47586Lysine-specific Demethylase Inhibitor (1C) (hydrochloride)CAS: 1234494-75-7纯度: >95.00%
An LSD1 inhibitor
- GC48084Sodium 4-Phenylbutyrate-d11CAS: 1392208-11-5纯度: >99.00%
An internal standard for the quantification of sodium 4-phenylbutyrate
- GC48263YW3-56 (hydrochloride) (technical grade)CAS: 2309756-20-3纯度: >80.00%
A PAD2 and PAD4 inhibitor
- GC48382Ac-QPKK(Ac)-AMCCAS: 1387005-23-3纯度: >98.00%
A fluorogenic substrate for SIRT1, SIRT2, and SIRT3
- GC48600Panobinostat-d4 (hydrochloride)纯度: >99.00%
An internal standard for the quantification of panobinostat
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC46892 | ATRA-BA Hybrid | 1037543-26-2 | >95.00% | |
A prodrug form of all-trans retinoic acid and butyric acid | ||||
| GC46900 | AZ9482 | 1825345-33-2 | >98.00% | |
A PARP inhibitor | ||||
| GC46935 | Bobcat 339 | 2280037-51-4 | >98.00% | |
Bobcat 339是一种具有良好选择性的新型胞嘧啶类TET酶抑制剂，对TET1和TET2的IC 50 值分别为33μM和73μM，但不抑制DNA甲基转移酶DNMT3a。 | ||||
| GC47050 | CAY10727 | 1671088-84-8 | >90.00% | |
A PAD3 inhibitor | ||||
| GC47055 | CAY10749 | 2337386-47-5 | >98.00% | |
A dual inhibitor of PARP and PI3K | ||||
| GC47056 | CAY10753 | - | >98.00% | |
A TNKS2 inhibitor | ||||
| GC47180 | Decitabine-15N4 | - | >95.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47294 | Entacapone-d10 | 1185241-19-3 | >99.00% | |
An internal standard for the quantification of entacapone | ||||
| GC47432 | Histone H3 (69-89) amide (human, mouse, rat, bovine) (trifluoroacetate salt) | - | >95.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47439 | Hydralazine-d4 (hydrochloride) | 2749234-32-8 | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47450 | IL-4 Inhibitor | 1332184-63-0 | >98.00% | |
An IL-4 inhibitor | ||||
| GC47579 | L-Pyrohomoglutamic Acid | 34622-39-4 | >95.00% | |
An amino acid building block | ||||
| GC47586 | Lysine-specific Demethylase Inhibitor (1C) (hydrochloride) | 1234494-75-7 | >95.00% | |
An LSD1 inhibitor | ||||
| GC47693 | m-Methoxybenzamide | 5813-86-5 | >98.00% | |
A PARP inhibitor | ||||
| GC48065 | SAHO | 29907-86-6 | >90.00% | |
A radical SAM enzyme substrate | ||||
| GC48066 | SAHO2 | 53199-56-7 | >95.00% | |
A radical SAM enzyme substrate | ||||
| GC48084 | Sodium 4-Phenylbutyrate-d11 | 1392208-11-5 | >99.00% | |
An internal standard for the quantification of sodium 4-phenylbutyrate | ||||
| GC48263 | YW3-56 (hydrochloride) (technical grade) | 2309756-20-3 | >80.00% | |
A PAD2 and PAD4 inhibitor | ||||
| GC48382 | Ac-QPKK(Ac)-AMC | 1387005-23-3 | >98.00% | |
A fluorogenic substrate for SIRT1, SIRT2, and SIRT3 | ||||
| GC48408 | TW9 | 2614417-90-0 | >98.00% | |
A dual inhibitor of BRD4 and HDAC1 | ||||
| GC48460 | NR-160 | 2484895-50-1 | >98.00% | |
An inhibitor of HDAC6 | ||||
| GC48463 | Bisubstrate Inhibitor 78 | 2368247-39-4 | >98.00% | |
An inhibitor of NNMT | ||||
| GC48495 | BMS-P5 | 1550371-22-6 | >99.50% | |
A PAD4 inhibitor | ||||
| GC48600 | Panobinostat-d4 (hydrochloride) | - | >99.00% | |
An internal standard for the quantification of panobinostat | ||||