Cell Cycle/Checkpoint
Cell Cycle/Checkpoint(细胞周期/检查点)
Cell Cycle
Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more
- ATM/ATR(29)
- Aurora Kinase(58)
- Cdc42(4)
- Cdc7(3)
- Chk(14)
- c-Myc(27)
- CRM1(8)
- Cyclin-Dependent Kinases(77)
- E1 enzyme(1)
- G-quadruplex(12)
- Haspin(6)
- HMTase(1)
- Kinesin(27)
- Ksp(4)
- Microtubule/Tubulin(257)
- Mps1(15)
- Mitotic(7)
- RAD51(13)
- ROCK(74)
- Rho(13)
- PERK(11)
- PLK(43)
- PTEN(6)
- Wee1(9)
- PAK(25)
- Arp2/3 Complex(8)
- Dynamin(14)
- ECM & Adhesion Molecules(54)
- Cytoskeleton & Motor Proteins(65)
- Endomembrane System & Vesicular Trafficking(36)
- G1(51)
- Genotoxic Stress(23)
- G2/M(40)
- G2/S(17)
- Inositol Phosphates(67)
- Proteolysis(183)
- Cellular Chaperones(14)
- Cyclin G-associated Kinase (GAK)(1)
- MARK(3)
- NEKs(1)
Cell Cycle/Checkpoint 相关产品(1379)
- GC16374MK-8776(SCH-900776)CAS: 891494-63-6纯度: >99.50%
MK-8776(SCH-900776) 是一种新型、选择性更高的Chk1抑制剂，旨在通过废除细胞周期阻滞来增强DNA损伤剂和抗代谢物的细胞毒性。
- GC16425Flavopiridol hydrochlorideCAS: 131740-09-5纯度: >98.00%
An inhibitor of cyclin-dependent kinases
- GC16607MesalamineCAS: 89-57-6纯度: >98.00%
An NSAID and active metabolite of sulfasalazine, balsalazide, and olsalazine
- GC16959NVP-LCQ195CAS: 902156-99-4纯度: >99.50%
NVP-LCQ195 (AT9311; LCQ195) 是 CDK1、CDK2、CDK3 和 CDK5 的小分子杂环抑制剂，IC50 为 1-42 nM。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC16167 | K 858 | 72926-24-0 | >99.50% | |
An inhibitor of Eg5 | ||||
| GC16265 | RS-1 | 312756-74-4 | >98.50% | |
A RAD51 activator | ||||
| GC16268 | Purvalanol B | 212844-54-7 | >98.50% | |
A CDK inhibitor | ||||
| GC16289 | SAR407899 hydrochloride | 923262-96-8 | >98.00% | |
A ROCK1 and ROCK2 inhibitor | ||||
| GC16374 | MK-8776(SCH-900776) | 891494-63-6 | >99.50% | |
MK-8776(SCH-900776) 是一种新型、选择性更高的Chk1抑制剂，旨在通过废除细胞周期阻滞来增强DNA损伤剂和抗代谢物的细胞毒性。 | ||||
| GC16391 | Amuvatinib (MP-470, HPK 56) | 850879-09-3 | >98.00% | |
A multi-targeted RTK inhibitor | ||||
| GC16413 | TMCB | 905105-89-7 | >98.00% | |
A dual inhibitor of CK2 and ERK8 | ||||
| GC16420 | THZ531 | 1702809-17-3 | >98.00% | |
An inhibitor of Cdk12 and Cdk13 | ||||
| GC16425 | Flavopiridol hydrochloride | 131740-09-5 | >98.00% | |
An inhibitor of cyclin-dependent kinases | ||||
| GC16429 | (R)-DRF053 dihydrochloride | 1241675-76-2 | - | |
cdk/CK1 inhibitor,potent and ATP-competitive | ||||
| GC16472 | ARQ 621 | 1095253-39-6 | - | |
An Eg5 inhibitor | ||||
| GC16475 | Afuresertib | 1047644-62-1 | >99.50% | |
A pan-Akt inhibitor | ||||
| GC16520 | Olomoucine | 101622-51-9 | >99.50% | |
An inhibitor of cyclin-dependent kinases | ||||
| GC16545 | GX-674 | 1432913-36-4 | - | |
GX-674是一种芳基磺酰胺类拮抗剂，可抑制Nav1.7通道，IC 50 值为0.1nM。 | ||||
| GC16607 | Mesalamine | 89-57-6 | >98.00% | |
An NSAID and active metabolite of sulfasalazine, balsalazide, and olsalazine | ||||
| GC16692 | Casin | 425399-05-9 | >98.00% | |
A Cdc42 GTPase inhibitor | ||||
| GC16727 | Flutax 1 | 191930-58-2 | >98.00% | |
荧光紫杉醇衍生物；微管染色 | ||||
| GC16741 | UNC0379 | 1620401-82-2 | >99.50% | |
A selective SET8 inhibitor | ||||
| GC16822 | LY2835219 | 1231930-82-7 | >99.00% | |
LY2835219是 CDK4 和 CDK6 的强效选择性抑制剂，在非细胞实验中的 IC 50 分别为 2nM 和 10nM。 | ||||
| GC16827 | ELR510444 | 1233948-35-0 | >98.00% | |
An inhibitor of tubulin polymerization | ||||
| GC16869 | Ixabepilone | 219989-84-1 | >99.50% | |
A broad-spectrum anticancer agent | ||||
| GC16941 | AZD6738 | 1352226-88-0 | >98.50% | |
AZD6738是一种具有口服活性和高效选择性的共济失调毛细血管扩张和Rad3相关蛋白（ATR）激酶抑制剂，IC 50 值为1nM。 | ||||
| GC16959 | NVP-LCQ195 | 902156-99-4 | >99.50% | |
NVP-LCQ195 (AT9311; LCQ195) 是 CDK1、CDK2、CDK3 和 CDK5 的小分子杂环抑制剂，IC50 为 1-42 nM。 | ||||
| GC17105 | CCT241533 hydrochloride | 1431697-96-9 | >99.00% | |
A selective Chk2 inhibitor | ||||