GLPBio

Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

研究方向

Neuroscience 相关产品(3932)

  • GC36145 structure
    GC36145Glabrolide
    CAS: 10401-33-9

    Glabrolide，来源于 Glycyrrhiza uralensis Fisch.，是一种 β 分泌脢 1 (BACE-1) 抑制剂。

  • GC36156 structure
    GC36156Glutaminyl Cyclase Inhibitor 3
    CAS: 2092921-50-9

    Glutaminyl Cyclase Inhibitor 3 (compound 212 ) 是一种具有抗阿尔兹海默症作用的化合物，是有效的人谷氨酰胺酰环化酶 (GC) 的抑制剂，其 IC50 值为 4.5 nM。Glutaminyl Cyclase-IN-1 (compound 212) 可显著降低大脑Aβ的浓度，并恢复认知功能。

  • GC36200 structure
    GC36200GW-406381
    CAS: 221148-46-5
    纯度: >99.50%

    A NSAID and COX-2 inhibitor

  • GC36209 structure
    GC36209Haloperidol D4
    CAS: 1189986-59-1

    An internal standard for the quantification of haloperidol

  • GC36247 structure
    GC36247Hoechst 34580 tetrahydrochloride
    CAS: 2310135-08-9
    纯度: >98.00%

    Hoechst 34580 tetrahydrochloride 是 Hoechst 系列染料，常用于活细胞的细胞核标记染色。

  • GC36278 structure
    GC36278Hydroxyzine D4 dihydrochloride

    Hydroxyzine D4二盐酸盐是Hydroxyzine氘代化合物标准品。

  • GC36279 structure
    GC36279Hydroxyzine pamoate
    CAS: 10246-75-0
    纯度: >99.50%

    Hydroxyzine Pamoate is the pamoate salt form of hydroxyzine, a synthetic piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties.

  • GC36291 structure
    GC36291Idalopirdine
    CAS: 467459-31-0

    A 5-HT 6 receptor antagonist

  • GC36305 structure
    GC36305Imrecoxib
    CAS: 395683-14-4
    纯度: >99.50%

    Imrecoxib（BAP-909）艾瑞昔布是选择性环氧合酶 2 (COX-2) 抑制剂，IC50 值为 18 nM，也可以抑制 COX1 活性，IC50 值为 115 nM。Imrecoxib（BAP-909) 艾瑞昔布具有抗炎作用。

  • GC36314 structure
    GC36314Indobufen
    CAS: 63610-08-2
    纯度: >99.50%

    Indobufen (Ibustrin, K 3920) is a reversible platelet aggregation inhibitor. Indobufen is a reversible inhibitor of platelet cyclooxygenase (Cox) activity and suppresses thromboxane synthesis.

  • GC36334 structure
    GC36334Isoeugenol acetate
    CAS: 93-29-8
    纯度: >99.50%

    Isoeugenol acetate 是一种肉豆蔻，丁香和肉桂的精油成分，对某些代谢酶如乙酰胆碱酯酶 (AChE) 酶 (IC50=77 nM; Ki=16 nM)，α-糖苷酶 (IC50=19.25 nM; Ki=21 nM) 和 α-淀粉酶 (IC50=411.5 nM) 具有良好的抑制作用。 Isoeugenol acetate 用于医疗和化妆品工业，具有抗氧化，抗癌，抗菌和抗炎特性。

  • GC36336 structure
    GC36336Isomerazin
    CAS: 1088-17-1
    纯度: >98.00%

    A coumarin with antioxidant and anti-inflammatory activities

  • GC36340 structure
    GC36340Isorosmanol
    CAS: 93780-80-4
    纯度: >98.00%

    Isorosmanol 是从鼠尾草叶中分离出的一种松香烷型二萜，具有抗氧化、神经保护和神经营养作用。Isorosmanol 能抑制 AChE 活性和黑色素的合成。

  • GC36370 structure
    GC36370JNJ-37822681 dihydrochloride
    CAS: 2108806-02-4
    纯度: >98.00%

    A dopamine D 2L receptor antagonist

  • GC36411 structure
    GC36411Kynurenic acid sodium
    CAS: 2439-02-3
    纯度: >99.50% / >98.00%

    Kynurenic acid sodium 是一种内源性色氨酸代谢物，是针对靶点 NMDA, glutamate, α7 nicotinic acetylcholine receptor 的光谱性拮抗剂。Kynurenic acid sodium 也是 GPR35/CXCR8 的激动剂。

  • GC36428 structure
    GC36428Lasmiditan hydrochloride
    CAS: 613677-28-4

    An Analytical Reference Standard

  • GC36442 structure
    GC36442Levetimide
    CAS: 21888-99-3
    纯度: >99.00%

    Levetimide 是一种有效的立体选择性 [3H](+)pentazocine 结合抑制剂，Ki 为 2.2 nM。

  • GC36476 structure
    GC36476Lodoxamide tromethamine
    CAS: 63610-09-3
    纯度: >99.00%

    A potent agonist of GPR35 and a mast cell stabilizer

  • GC36482 structure
    GC36482Loxoprofen
    CAS: 68767-14-6
    纯度: >99.50%

    An NSAID and a prodrug form of loxoprofen-SRS

  • GC36501 structure
    GC36501LY 344864 hydrochloride
    CAS: 1217756-94-9

    A 5-HT 1F receptor antagonist

  • GC36502 structure
    GC36502LY 344864 racemate
    CAS: 186543-64-6
    纯度: >98.50%

    LY 344864 racemate 是一种 5-HT1F 受体激动剂, 来自专利 US 5708187 A。

  • GC36503 structure
    GC36503LY 344864 S-enantiomer
    CAS: 186544-27-4
    纯度: >99.50%

    LY 344864 S-enantiomer 是 LY344864 的 S 型对映体。LY344864 是 5-HT1F 受体激动剂。

  • GC36510 structure
    GC36510LY3130481
    CAS: 1610802-47-5
    纯度: >99.00%

    LY3130481 是一种跨膜 AMPA 受体调节蛋白 TARP γ-8 依赖性的 AMPA 受体拮抗剂，选择性抑制 AMPA/TARP γ-8 的 IC50 值为 65 nM。

  • GC36511 structure
    GC36511LY334370
    CAS: 182563-08-2
    纯度: >99.50%

    A 5-HT 1F receptor agonist