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Home >> Signaling Pathways >> Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. 产品名称 Information
  2. GC17729 SKF38393 HCl

    (±)-SKF-38393 hydrochloride; SKF-38393A

     SKF38393 HCl 是一种多巴胺 D1 受体 (D1DR) 的选择性激动剂，IC50 为 110 nM。
  3. GC37652 Smilagenin

    Smilagenin (SMI) 是一种脂溶性小分子甾体皂苷元，来自知母 Rhizoma anemarrhenae 和天竺葵 Radix asparagi，广泛用于治疗慢性神经退行性疾病的中药。Smilagenin (SMI) 通过增加毒蕈碱受体亚型 1 (M1)-受体的的密度来改善老年大鼠的记忆。Smilagenin (SMI) 通过刺激脑源性神经营养因子的基因表达减弱 Aβ(25-35) 诱导的神经变性，可能代表 AD 的新型治疗策略。
  4. GC12123 sn-Glycero-3-phosphocholine

    甘磷酸胆碱; Choline Alfoscerate; Alpha-GPC; L-α-GPC

     A nootropic phospholipid
  5. GC48082 sn-glycero-3-Phosphocholine-d9

    Glycerophosphocholine-d9, L-α-Glycerophosphorylcholine-d9, L-α-GPC-d9, sn-glycero-3-PC-d9

     A neuropeptide with diverse biological activities
  6. GC48083 sn-Glycerol-3-phosphate (cyclohexyl ammonium salt hydrate)

    G3P

     A neuropeptide with diverse biological activities
  7. GC17846 SNAP 94847 hydrochloride An antagonist of MCH1
  8. GC12013 Sodium salicylate

    水杨酸钠; Salicylic acid sodium salt; 2-Hydroxybenzoic acid sodium salt

     水杨酸钠（水杨酸钠盐）抑制环加氧酶 2（COX-2）活性，与转录因子（NF-κB）激活无关。
  9. GC37662 Sofiniclin

    ABT 894

     Sofiniclin (ABT 894) 是nAChR的激动剂，是一种有潜力的非兴奋剂来，可用于注意力缺陷症的研究。
  10. GC63196 Sofpironium bromide

    BBI 4000

     Sofpironium bromide (BBI 4000) 是一种抗胆碱能剂，用于研究原发性腋窝多汗症 (PAH)。Sofpironium bromide 通过抑制应用部位外分泌腺中的 M3 毒蕈碱受体来减少出汗。Sofpironium bromide 对 M1、M2、M4 和 M5 亚型也有很高的亲和力。
  11. GC31407 Sograzepide (Netazepide)

    Netazepide; YF 476; YM-220

     Sograzepide (Netazepide)是一种口服活性高、选择性强且效力强的胃泌素/CCK-B拮抗剂，IC50值为 0.1nM，对胃泌素/CCK-A活性具有抑制作用，IC50为502nM。
  12. GC30822 Solifenacin (YM905)

    索利那新; YM905 free base

    Solifenacin (YM905) is a competitive muscarinic receptor antagonist. The binding of acetylcholine to these receptors, particularly the M3 receptor subtype, plays a critical role in the contraction of smooth muscle.
  13. GC10508 Solifenacin hydrochloride

    索利那新盐酸盐,YM905 hydrochloride

     Solifenacin hydrochloride (YM905 hydrochloride) 是一种毒蕈碱受体拮抗剂，对 M1、M2 和 M3 受体的 pKis 分别为 7.6、6.9 和 8.0。
  14. GC44912 Solifenacin N-Glucuronide A metabolite of solifenacin
  15. GC44913 Solifenacin N-oxide

    索利那新N-氧化物

     An inactive metabolite of solifenacin
  16. GC17182 Solifenacin succinate

    索非那新琥珀酸盐; YM905

     A muscarinic M1, M2, and M3 receptor antagonist
  17. GC49196 Solifenacin-d5 (succinate)

    YM905-d5

     An internal standard for the quantification of solifenacin
  18. GC39184 Solriamfetol Solriamfetol (JZP-110) 是一种口服有效的，选择性的多巴胺和去甲肾上腺素再摄取抑制剂，对多巴胺和去甲肾上腺素转运蛋白的 IC50 分别为 2.9 μM 和 4.4 μM。Solriamfetol 具有强大的促唤醒作用。
  19. GC49123 Somatorelin (1-44) amide (human) (trifluoroacetate salt)

    Growth Hormone-releasing Factor (1-44) amide, hpGRF-44, Human Pancreas GRF-44, Somatoliberin

     A synthetic GHRH peptide
  20. GC44914 Somatostatin-14 (acetate) A cyclic peptide hormone
  21. GC49483 Somatostatin-28 (1-14) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) An N-terminal fragment of somatostatin-28
  22. GC49574 Somatostatin-28 (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) A cyclic neuropeptide hormone
  23. GC12015 Sonepiprazole

    PNU-101387G; U-101387G

     A selective D4 receptor antagonist
  24. GC33067 Sophoflavescenol

    槐苦参醇

     Sophoflavescenol是一种异戊烯基黄酮类化合物，能够抑制PDE5的活性，IC50值为0.013μM；同时抑制RLAR，HRAR，BACE1，AChE和BChE，IC50值分别为0.30µM，0.17µM，10.98µM，8.37µM和8.21µM。
  25. GC61286 SP-8356 SP-8356, an anti-inflammatory synthetic verbenone derivative, is a CD147 inhibitor with respect to its regulation of breast cancer cell behavior and cancer progression.
  26. GC52449 Spadin (trifluoroacetate salt)

    YAPLPRWSGPIGVSWGLR

     An inhibitor of K2P2.1/TREK1
  27. GC14301 Spaglumic acid

    异冬谷酸,N-Acetylaspartylglutamic acid

     A peptide neurotransmitter
  28. GC11280 Spantide I Spantide I是一种与P物质（SP）类似的具有选择性的NK1受体拮抗剂，其对NK1和NK2受体的Ki值分别为230nM和8150nM。
  29. GC69933 Spantide I TFA Spantide I TFA 是substance P 的类似物，是选择性的神经激肽-1 受体 (NK1 receptor) 的拮抗剂，其对NK1 和NK2 受体的Ki 值分别为 230 nM 和8150 nM。Spantide I可减少感染角膜的1型细胞因子和增强2型细胞因子IL-10，从而显著减少角膜穿孔。
  30. GC31020 SPD-473 citrate SPD-473citrate是5-HT/多巴胺/去甲肾上腺素再摄取抑制剂。
  31. GC49341 Spermidine-d6 An internal standard for the quantification of spermidine
  32. GC14953 Spermine

    精胺,Gerontine,Musculamine,Neuridine,NSC 268508,1,5,10,14-Tetraazatetradecane

     A natural polyamine
  33. GC52390 Spexin 1 (human, mouse, rat, bovine) (acetate)

    Neuropeptide Q, NPQ, NWTPQAMLYLKGAQ-NH2, SPX1

     An endogenous peptide and agonist of GAL2 and GAL3
  34. GC44926 Sphinganine-1-phosphate (d17:0)

    C17 Sphinganine-1-phosphate (d17:0), D-erythro-Sphinganine-C17-1-phosphate, dihydro-D-erythro-Sphingosine-C17-1-phosphate

     A sphingolipid
  35. GC48088 Sphingomyelins (buttermilk)

    SMs (buttermilk)

     A sphingolipid
  36. GC41279 Sphingosine (d20:1)

    D-erythro-Sphingosine C20

     A lipid component of CNS gangliosides
  37. GC44934 Sphingosine-1-phosphate (d16:1)

    C16 S1P, C16 Sphingosine-1-phosphate, S1P (d16:1)

     A derivative of S1P
  38. GC46035 Sphingosine-1-phosphate-d7 (d18:1)

    鞘氨醇-1-磷酸酯-D7(D18:1),S1P-d7 (d18:1), Sphingosine-1-Phosphoric Acid-d7

     An internal standard for the quantification of S1P
  39. GC60345 Sphondin

    牛防风素

     Sphondin可从Heracleumlaciniatum中分离，对IL-1β诱导的A549细胞中COX-2蛋白和PGE2释放水平的升高具有抑制作用。
  40. GC74243 Spinacetin Spinacetin是从日本菊中分离得到的天然产物。
  41. GC48092 Spinosad

    LY232105, XDE-105

     A naturally-occurring insecticide
  42. GC16082 Spinosyn A

    多杀霉素 A

     A naturally-occurring insecticide
  43. GC44938 Spinosyn D

    多杀霉素D

     Spinosyn D是一种杀虫剂，属于斯皮诺素家族，由土壤放线菌Saccharopolyspora spinosa发酵产生，在潮湿的土壤中有氧孵化DT50值为14.5天。
  44. GC44940 Spinosyn D aglycone

    多杀菌素D苷元

     An aglycone form of spinosyn D
  45. GC64885 Spiperone

    螺哌隆,Spiroperidol

     Spiperone 是一种有效的 dopamine D2、血清素 5-HT1A 和血清素 5-HT2A 对手。Spiperone 是一种广泛使用的药理学工具。Spiperone 具有研究神经系统疾病的潜力。
  46. GC41258 Spiroxamine

    螺噁茂胺

     A fungicide
  47. GC91208 Spiroxamine-d4

    一种用于测量斯比洛克胺的内部标准
  48. GC11256 SR 140333

    SR140333

     SR 140333 (SR140333) 是一种有效的、选择性的、竞争性的、非肽速激肽 NK1 受体拮抗剂。
  49. GC48100 SR 142948 (hydrochloride) A neuropeptide with diverse biological activities
  50. GC31613 SR 146131

    SR146131是一种有效，有口服活性，选择性的非多肽缩胆囊素1(cholecystokinin1)受体激动剂。
  51. GC13052 SR 16584 Selective antagonist of α3β4 nicotinic acetylcholine receptors

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