Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC69495 MRK-898 MRK-898 是一种口服有效的 GABA(A) 受体调节剂。MRK-898 结合 GABA 受体的 α1、α2、α3 和 α5 亚基，Ki 值分别为 1.2 nM、1.0 nM、0.73 nM 和 0.50 nM。然而，含有 α1 的 GABA(A) 受体被鉴定为"镇静"受体，而含有 α2 和/或 α3 的受体被鉴定为"抗焦虑"亚型。
GC31036 MRZ 2-514 MRZ2-514是一种NMDAreceptor(glycineB)的拮抗剂，Ki值为33μM。
GC92099 MSG606 (trifluoroacetate salt)

cyclo(CH₂)₃CO-Gly-His-D-Phe-Arg-D-Trp-Cys)-Asp-Arg-Phe-Gly-NH₂
MSG606 (trifluoroacetate salt)是黑皮质素受体1的肽拮抗剂（MC1R；对人类受体的IC50=17 nM）和γ-黑素细胞刺激激素（γ-MSH）的衍生物。
GC91914 MSH Release-Inhibiting Factor (trifluoroacetate salt)

Melanocyte-stimulating Hormone Release-Inhibiting Factor; MIF-1; MSH-R-IF
MSH Release-Inhibiting Factor (trifluoroacetate salt) (MSH-R-IF)是一种与大鼠纹状体结合的下丘脑三肽（Kd = 4.69 nM），具有多种生物活性。
GC17185 MSOP MSOP 是一种选择性 III 族代谢型谷氨酸受体拮抗剂，对 L-AP4 敏感的突触前 mGluR 的表观 KD 为 51 μM。
GC13548 MSPG mGlu receptor antagonist
GC74011 MT-1207 MT-1207是一种口服活性和选择性肾上腺素能α1和5-HT2A受体拮抗剂。
GC48399 MTP 131 (acetate)

Elamipretide, SS-31
A mitochondria-targeted peptide antioxidant
GC11428 MTPG MTPG 是一种有效的 mGluR2 和 mGluR3 拮抗剂。
GC45515 MX1013

CV1013; Z-VD-FMK
A dipeptide pan-caspase inhibitor
GP10006 Myelin Basic Protein (68-82), guinea pig

豚鼠髓磷脂碱性蛋白片段68-82,H2N-Tyr-Gly-Ser-Leu-Pro-Gln-Lys-Ser-Gln-Arg-Ser-Gln-Asp-Glu-Asn-OH
髓鞘碱性蛋白 (68-82)，豚鼠是髓鞘碱性蛋白 (MBP) 的片段。
GC52385 Myelin Basic Protein (85-99) Peptide Antagonist (trifluoroacetate salt)

EKPKVEAYKAAAAPA-OH, MBP (85-99) Peptide Antagonist
An MBP (85-99) antagonist
GP10130 Myelin Basic Protein (87-99)

Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro

An encephalitogenic peptide
GC44257 Myelin Basic Protein (87-99) (human, bovine, rat) (trifluoroacetate salt)

MBP
An encephalitogenic peptide
GC14588 Myosmine

麦斯明
A minor tobacco alkaloid
GC49269 Myr-ZIP

Myristoylated-ZIP, Myristoylated Zeta-Pseudosubstrate Inhibitory Peptide, Myr-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu, Myr-SIYRRGARRWRKL-OH, Ζeta Inhibitory Peptide
A PKMζ inhibitor
GC52049 Myricetin 3-galactoside

杨梅素 3-O-半乳糖苷
A flavonoid with diverse biological activities
GC44259 Myristicin

肉豆蔻醚,Myristicine
An Analytical Reference Standard
GC47809 Nε-(1-Carboxymethyl)-L-lysine-d3

CML-d3
A neuropeptide with diverse biological activities
GC16487 Nα-Methylhistamine dihydrochloride
histamine H3 receptor agonist
GC45838 N,N-Dipropyldopamine (hydrobromide)

N,N-二丙基多巴胺氢溴酸盐
A dopamine receptor agonist
GC44270 N-(α-Linolenoyl) Tyrosine

NALT
Novel dietary CNS dopamine enhancing lipid
GC41361 N-(1-(3,4-Dihydroxyphenyl)propan-2-yl)oleamide A modulator of the CB₁ receptor and PPARα
GC44264 N-(2,6-Dimethylphenyl)-2-(ethylmethylamino)acetamide (hydrochloride)

利多卡因杂质K
A lidocaine impurity
GC17980 N-(2-phenylethyl)-Indomethacin amide

N-2PIA
A selective, reversible inhibitor of COX-2
GC15372 N-(3-hydroxyphenyl)-Arachidonoyl amide

3-HPAA
An irreversible COX-2 inhibitor
GC15959 N-(3-pyridyl)-Indomethacin amide

N-3PyIA
Potent and selective reversible inhibitor of COX-2
GC10611 N-(4-acetamidophenyl)-Indomethacin amide

N-4AIA
Potent and selective reversible inhibitor of COX-2
GC44293 N-Acetyl ACTH (1-17) (human) (trifluoroacetate salt)

Ac-SYSMEHFRWGKPVGKKR, N-Acetyl Adrenocorticotropic Hormone (1-17)
An N-terminal peptide fragment of ACTH
GC18463 N-acetyl Histamine

N-Ω-乙酰基组胺,N-Omega-acetylhistamine
A histamine metabolite
GC44298 N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid

N-乙酰-2,3-二脱氢-2-脱氧神经氨酸,Neu5Ac2en; DANA
N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid是一种高效的哺乳动物唾液酸酶（神经氨酸酶）抑制剂。
GC16440 N-acetyl-2-carboxy Benzenesulfonamide A COX-1/COX-2 inhibitor
GC47737 N-acetyl-L-Cysteine ethyl ester

N-乙酰-L-半胱氨酸乙酯,N-Acetylcysteine ethyl ester; NACET
An esterified form of NAC
GC44300 N-Acetylagmatine (acetate salt)

Monoacetylagmatine
A potential derivative of agmatine
GC13222 N-Acetylglycyl-D-glutamic acid Excitatory peptide that induces seizures
GC18506 N-Arachidonoyl Dopamine

NADA
An arachidonoyl amino acid and CB₁ receptor agonist
GC47748 N-Arachidonoyl Dopamine-d8

NADAd8
An internal standard for the quantification of N-arachidonoyl dopamine
GC44318 N-Arachidonoyl-3-hydroxy-γ-Aminobutyric Acid

NAG3HABA
An arachidonoyl amino acid
GC44319 N-Arachidonoyl-L-Alanine

NALA
An uncharacterized, natural arachidonoyl amino acid
GC74716 N-Biotinyl p-aminophenyl arsenic acid N-Biotinyl p-aminophenyl arsenic acid是一种双功能试剂，可以与链霉抗生物素蛋白和二硫醇结合。
GC44342 N-Decanoyl p-Nitroaniline

DepNA
A colorimetric FAAH substrate used for enzyme activity measurement
GC68335 N-Demethyl MK-6884 N-Demethyl MK-6884 (化合物 34) 是一种有效的 M4 mAChR 变构调节剂。N-Demethyl MK-6884 可用于阿尔茨海默症和由 M4 mAChR 介导的其他疾病的研究。
GC49210 N-desethyl Brinzolamide (oxalate)

AL 8520
An active metabolite of brinzolamide
GC49764 N-desmethyl Asenapine

阿塞那平D4
A metabolite of asenapine
GC52132 N-desmethyl Diltiazem (hydrochloride)

盐酸地尔硫卓杂质D
An active metabolite of diltiazem
GC49219 N-desmethyl Eletriptan

N-去甲基依曲普坦
A metabolite of eletriptan
GC48804 N-desmethyl Olanzapine

N-去甲基奥氮平
A major metabolite of olanzapine
GC49583 N-desmethyl Sertraline (hydrochloride)

N-desmethyl Sertraline
A metabolite of sertraline
GC49794 N-desmethyl Trimipramine

N-去甲曲米帕明
An active metabolite of trimipramine
GC41270 N-desmethyl Zolmitriptan

N-去甲佐米曲坦-D3
An active metabolite of zolmitriptan