GlpBio

Sultopride hydrochloride (LIN-1418 hydrochloride)

目录号: GC30944纯度: >98.00%同义词: 盐酸舒必利; LIN-1418 hydrochloride
Sultopride hydrochloride (LIN-1418 hydrochloride) (LIN-1418 hydrochloride) 是多巴胺 D2 受体的选择性拮抗剂。
Sultopride hydrochloride (LIN-1418 hydrochloride)
Cas No.: 23694-17-9
规格价格库存数量操作
1mg¥378.00现货
1
5mg¥900.00现货
1
10mg¥1,440.00现货
1
25mg¥2,880.00现货
1
50mg¥4,590.00现货
1
10mm*1mlinwater¥990.00现货
1
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产品描述 Description

Sultopride hydrochloride is a selective antagonist of dopamine D2 receptor.

Sultopride hydrochloride is a selective antagonist of dopamine D2 receptor. DOPAC and HVA levels in the striatum, the nucleus accumbens and the medial prefrontal cortex are higher in the rats treated with Sultopride hydrochloride and sulpiride than those of the controls. In the striatum, DOPAC and HVA levels are higher in the Sultopride hydrochloride-treated rats than the sulpiride-treated rats (p<0.05). In the nucleus accumbens, DOPAC levels are higher in the Sultopride hydrochloride-treated rats than sulpiride treated rats (p<0.05). In the Sultopride hydrochloride-treated rats, DOPAC and HVA levels are higher in the striatum or in the nucleus accumbens than in the medial prefrontal cortex (p<0.05)[1].

[1]. Moriuchi K, et al. Differences in effects of sultopride and sulpiride on dopamine turnover in rat brain. Neurochem Res. 1995 Jan;20(1):95-9.

实验参考方法 Experimental Reference Method

Animal experiment:

Thirty-six male Sprague-Dawley rats weighing 180 to 220 g are used in this study. The rats are divided into three groups of 6 each. One group is intraperitoneally injected with Sultopride hydrochloride (100 mg/kg body weight), the second group with sulphide (100 mg/kg body weight), and the third group with normal saline. One hundred minutes after the initial treatments, apomorphine (0.1 mg/kg body weight, dissolved in saline ad libitum) is administered subcutaneously to the three groups, and 20 minutes later the rats are sacrificed. The third group serves as controls[1].

References:

[1]. Moriuchi K, et al. Differences in effects of sultopride and sulpiride on dopamine turnover in rat brain. Neurochem Res. 1995 Jan;20(1):95-9.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
23694-17-9
同义词
盐酸舒必利; LIN-1418 hydrochloride
SMILES
O=C(NCC1N(CC)CCC1)C2=CC(S(=O)(CC)=O)=CC=C2OC.Cl
分子式
C17H27ClN2O4S
分子量
390.93 g/mol
溶解性
DMSO : 50 mg/mL (127.90 mM);Water : 50 mg/mL (127.90 mM)
保存条件
Store at -20&#176;C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol