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Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

研究方向

Neuroscience 相关产品(3932)

  • GC26035 structure
    GC26035Verubecestat (MK-8931) Trifluoroacetate
    CAS: 2095432-65-6

    Verubecestat (MK-8931) Trifluoroacetate is a potent and selective beta-secretase inhibitor and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor.

  • GC26056 structure
    GC26056WAY-303290
    CAS: 323176-64-3

    WAY-303290 (GluR6 antagonist-1) is a benzothiophene derivative acting as an ionotropic glutamate receptor 6 (GluR6) antagonist, which can be used for researching acute and chronic neurological disorders.

  • GC26093 structure
    GC26093α-Conotoxin GI
    CAS: 76862-65-2

    α-Conotoxin GI, a 13-residue peptide originally isolated from the venom of the fish-hunting cone snail Conus geographus, acts as a competitive antagonist for the muscle-type nicotinic acetylcholine receptor (nAChR) with excellent selectivity for α/δ receptor subunit binding over α/γ.

  • GC26144 structure
    GC26144Menthol
    CAS: 1490-04-6

    Menthol 是个天然的止痛剂。Menthol 通过抑制神经元细胞膜的 Ca ++ 电流，刺激冷感受器，从而产生凉的感觉。

  • GC26151 structure
    GC26151(−)-Apomorphine (hydrochloride hydrate)
    CAS: 58117-94-5
    纯度: >95.00%

    (-)-Apomorphine (hydrochloride hydrate)是一种强效的多巴胺受体激动剂，对D1-和D2类受体（D1、D2S、D2L、D3、D4、D5）都具有广泛作用。

  • GC26184 structure
    GC26184Kynurenic acid-d5
    CAS: 350820-13-2
    纯度: >98.00%

    Kynurenic acid-d 5 是 Kynurenic acid 的氘代物。

  • GC26199 structure
    GC261991-heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine
    CAS: 50930-23-9
    纯度: >99.00% / >98.00%

    1-heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine是血液中存在的一种内源性代谢物，可作为小鼠模型抑郁症的诊断生物标志物。

  • GC26233 structure
    GC26233Docosahexaenoic Acid-d5
    CAS: 1197205-71-2
    纯度: >99.00%

    Docosahexaenoic acid-d5 (DHA-d5) is intended for use as an internal standard for the quantification of DHA (Item No. 90310) by GC- or LC-MS.

  • GC26265 structure
    GC26265α-Hydroxyglutaric acid disodium
    CAS: 40951-21-1
    纯度: ≥98.00%

    α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium 是戊二酸的 α-羟基酸形式。

  • GC26338 structure
    GC26338α-Cypermethrin
    CAS: 67375-30-8
    纯度: >99.00%
  • GC30008 structure
    GC30008Ceruletide (Caerulein)
    CAS: 17650-98-5
    纯度: >99.50%

    Ceruletide 作为一种十肽和一种有效的胆囊收缩剂，对人类和动物的胆囊肌肉和胆管具有直接的痉挛作用。

  • GC30027 structure
    GC30027S-(+)-Marmesin ((+)-Marmesin)
    CAS: 13849-08-6
    纯度: >98.00%

    A coumarin with anticancer activity

  • GC30051 structure
    GC30051Methylene Blue (Basic Blue 9)
    CAS: 61-73-4
    纯度: >98.00% / >99.00%

    Methylene Blue (Basic Blue 9, Tetramethylthionine chloride, methylthioninium chloride, CI-52015) is used as a dye in chromoendoscopy. It Inhibits tau filament formation with IC50 of 1.9μM. Also it inhibits soluble guanylyl cyclase.

  • GC30088 structure
    GC30088Fluxametamide
    CAS: 928783-29-3
    纯度: >98.50% / >98.00%

    Fluxametamide是一种GABA和谷氨酸门控氯离子通道的拮抗剂，对GABACls和GluCls的IC 50 值分别为1.95nM和225nM。

  • GC30104 structure
    GC30104Fezolinetant (ESN-364)
    CAS: 1629229-37-3
    纯度: >98.00%

    Fezolinetant (ESN-364) 是一种神经激肽 3 受体 (NK3R) 的拮抗剂，用于治疗更年期潮热。

  • GC30112 structure
    GC30112PAT-1251
    CAS: 2007885-39-2
    纯度: >99.50%

    PAT-1251是一种赖氨酰氧化酶样蛋白2（LOXL2；IC 50 =0.71μM）抑制剂。

  • GC30198 structure
    GC30198Dolasetron Mesylate hydrate
    CAS: 878143-33-0
    纯度: >99.00%

    A 5-HT 3 receptor antagonist

  • GC30206 structure
    GC30206Roluperidone (CYR-101)
    CAS: 359625-79-9
    纯度: >99.50%

    A dual antagonist of 5-HT 2A and σ 2 receptors

  • GC30212 structure
    GC30212(S)-Willardiine ((-)-Willardiine)
    CAS: 21416-43-3
    纯度: >99.00% / >99.50%

    (S)-Willardiine ((-)-Willardiine)是一种强效的AMPA/kainate受体激动剂，EC 50 值为45μM。

  • GC30218 structure
    GC30218Minaprine
    CAS: 25905-77-5

    Minaprine dihydrochloride is hydrochloride salt form of Minaprine, which acts as a reversible inhibitor of MAO-A in rats and weakly inhibit acetylcholinesterase in rat brain (striatum) homogenates.

  • GC30241 structure
    GC30241GSK598809
    CAS: 863680-45-9
    纯度: >99.50%

    GSK598809是多巴胺D3受体(DRD3)的选择性拮抗剂，其pKi值为8.9。

  • GC30273 structure
    GC30273Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide)
    CAS: 960151-65-9
    纯度: >99.50%

    Tedatioxetine (Lu AA24530) hydrobromide 可作为 5-HT2A、5-HT2C、5-HT3 和 α；1A-肾上腺素受体拮抗剂，可作为 5-羟色胺和去甲肾上腺素 (NE) 的首选三重再摄取抑制剂 (TRI)。

  • GC30280 structure
    GC30280Chlorpromazine D6 hydrochloride
    CAS: 1228182-46-4
    纯度: >99.50%

    Chlorpromazine D6 hydrochloride是 Chlorpromazine 的氘代物，可被用于 NMR、GC-MS 或 LC-MS 分析中的内标品，用于定量分析。

  • GC30290 structure
    GC30290Neostigmine methyl sulfate
    CAS: 51-60-5
    纯度: >99.50%

    A reversible acetylcholinesterase inhibitor