Neuroscience
Neuroscience(神经科学)
Neuroscience
Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more
- 5-HT Receptor(442)
- AChR(58)
- AChE(103)
- Alzheimer(115)
- Amyloid β(131)
- BACE(5)
- CGRP (34)
- COX(302)
- DAPK(7)
- Dopamine Receptor(312)
- GABA Receptor(168)
- Gap Junction(18)
- GluR(121)
- Histamine(3)
- Histamine Receptor(243)
- mPEGS-1(4)
- Muscarinic Receptor(43)
- Neuroscience Peptides(48)
- Nicotinic Receptor(66)
- P2 Receptor(2)
- P2X7 receptor(4)
- SSRIs(8)
- Substance P/NK1 Receptor(22)
- NMDA(2)
- Beta-secretase(25)
- CaMK(33)
- Dopamine Transporter(20)
- Monoamine Oxidase(91)
- Serotonin Transporter(57)
- nAChR(103)
- iGluR(163)
- Neurokinin Receptor(75)
- MCHR1 (GPR24)(16)
- mAChR(185)
- GPR139(4)
- Cholecystokinin Receptor(25)
- Behavioral Neuroscience(372)
- DREADD(1)
- Huntington(17)
- Neuroendocrinology(65)
- Neuroprotection(128)
- Ophthalmology(168)
- Pain Research(241)
- Parkinson(78)
- Prion(7)
- Seizure Disorders(99)
- Cholinesterases(13)
- AAK1
- Huntingtin
- α-synuclein
- Transthyretin (TTR)
- Tau Protein(4)
- Neurodegenerative Disorders(7)
- Cholinesterase (ChE)(4)
- Amyloid-β(9)
- γ-secretase(1)
- Ischemia(3)
Neuroscience 相关产品(3932)
- GC91909Fenoprofen-13C6 (sodium salt hydrate)CAS: 2687960-29-6纯度: >98.00%
Fenoprofen-13C6 (sodium salt hydrate)旨在用作通过GC或LC-MS定量非诺洛芬的内标。
- GC91914MSH Release-Inhibiting Factor (trifluoroacetate salt)纯度: >95.00%
MSH Release-Inhibiting Factor (trifluoroacetate salt) (MSH-R-IF)是一种与大鼠纹状体结合的下丘脑三肽（Kd = 4.69 nM），具有多种生物活性。
- GC91921FenclofenacCAS: 34645-84-6纯度: >95.00%
Fenclofenac是一种非甾体抗炎药（NSAID）和COX抑制剂（COX-1和COX-2的IC50分别为7和4μM）。
- GC91946HexylHIBO (hydrobromide)纯度: >98.00%
HexylHIBO (hydrobromide)是I组代谢性谷氨酸受体(mGluRs；mGluR1α和mGluR5a的Kbs分别为140 μM和110 μM)。
- GC91977TrkB Agonist Prodrug R13CAS: 1609067-49-3纯度: >95.00%
TrkB Agonist Prodrug R13（R13）是原肌球蛋白相关激酶B（TrkB）激活剂7,8-二羟基黄酮的前药形式。
- GC91985Alloisolithocholic Acid-d4CAS: 2410277-60-8纯度: >99.00%
Alloisolithocholic Acid-d4用于GC-或LC-MS定量别异石胆酸的内标。
- GC92004DPTIP (hydrochloride)CAS: 2361799-64-4纯度: >95.00%
DPTIP (hydrochloride)是中性鞘磷脂酶2nMase2的抑制剂；IC50=30 nM。
- GC92078PKG Inhibitor (trifluoroacetate salt)纯度: >95.00%
PKG Inhibitor (trifluoroacetate salt)是一种特定的cGMP依赖性PKG抑制剂Ki=86μM。
- GC92095Ac-(D-Arg)-CEH-(D-Phe)-RWC-NH2 (trifluoroacetate salt)纯度: >98.00%
Ac-(D-Arg)-CEH-(D-Phe)-RWC-NH2 (trifluoroacetate salt)是一种环肽和黑素皮质素受体4 （MC4R）的激动剂。
- GC92097TCMCB07 (trifluoroacetate salt)纯度: >98.00%
TCMCB07 (trifluoroacetate salt)是黑色素皮质素受体1 （MC1R）、MC3R、MC4R和MC5R的肽拮抗剂（ic50对人类受体分别为19.5、0.59、13.58和8.07 nM）。
- GC92098HS-024 (trifluoroacetate salt)纯度: >98.00%
HS-024 (trifluoroacetate salt)是黑皮质素受体4的环肽拮抗剂（MC4R；Ki=0.29nM）。
- GC92099MSG606 (trifluoroacetate salt)纯度: >95.00%
MSG606 (trifluoroacetate salt)是黑皮质素受体1的肽拮抗剂（MC1R；对人类受体的IC50=17 nM）和γ-黑素细胞刺激激素（γ-MSH）的衍生物。
- GC92100Neuropeptide EI (rat) (trifluoroacetate salt)纯度: >95.00%
Neuropeptide EI (rat) (trifluoroacetate salt)是大鼠前黑色素浓缩激素MCH的内源性肽片段，参与激素释放、梳理行为和运动活动。
- GC92101γ1-MSH (human, mouse, rat, bovine) (trifluoroacetate salt)纯度: >95.00%
γ1-MSH (human, mouse, rat, bovine) (trifluoroacetate salt)是一种肽激素，由垂体中的前皮黑皮质素（POMC）翻译后加工产生。
- GC92102γ1-MSH (human, mouse, rat, bovine) (acetate)纯度: >95.00%
γ1-MSH (human, mouse, rat, bovine) (acetate)是一种肽激素，由垂体中的前皮黑皮质素（POMC）翻译后加工产生。
- GC92103HS-014 (trifluoroacetate salt)纯度: >98.00%
HS-014 (trifluoroacetate salt)是黑素皮质素受体4mc4r的拮抗剂；Ki = 3.16 nM。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC91906 | (R)-AS-1 | 2506367-95-7 | >95.00% | |
(R)-AS-1是兴奋性氨基酸转运蛋白2 EAAT2的正变构调节剂；谷氨酸摄取试验中的EC50=11nM。 | ||||
| GC91909 | Fenoprofen-13C6 (sodium salt hydrate) | 2687960-29-6 | >98.00% | |
Fenoprofen-13C6 (sodium salt hydrate)旨在用作通过GC或LC-MS定量非诺洛芬的内标。 | ||||
| GC91910 | Ferroptosis Inhibitor D1 | - | >98.00% | |
Ferroptosis Inhibitor D1是一种自由基清除剂和铁下垂抑制剂。 | ||||
| GC91911 | Napirimus | 70696-66-1 | >95.00% | |
Napirimus是一种免疫抑制剂。 | ||||
| GC91914 | MSH Release-Inhibiting Factor (trifluoroacetate salt) | - | >95.00% | |
MSH Release-Inhibiting Factor (trifluoroacetate salt) (MSH-R-IF)是一种与大鼠纹状体结合的下丘脑三肽（Kd = 4.69 nM），具有多种生物活性。 | ||||
| GC91920 | Rhein-13C6 | - | >95.00% | |
Rhein-13C6旨在用作GC或LC-MS定量大黄酸的内标。 | ||||
| GC91921 | Fenclofenac | 34645-84-6 | >95.00% | |
Fenclofenac是一种非甾体抗炎药（NSAID）和COX抑制剂（COX-1和COX-2的IC50分别为7和4μM）。 | ||||
| GC91946 | HexylHIBO (hydrobromide) | - | >98.00% | |
HexylHIBO (hydrobromide)是I组代谢性谷氨酸受体(mGluRs；mGluR1α和mGluR5a的Kbs分别为140 μM和110 μM)。 | ||||
| GC91947 | BH400 | - | >95.00% | |
BH400是过氧化物酶体增殖物激活受体α (PPARα)的激动剂和干扰素基因刺激因子抑制剂(STING；Ic50 = 8.1 μm)。 | ||||
| GC91977 | TrkB Agonist Prodrug R13 | 1609067-49-3 | >95.00% | |
TrkB Agonist Prodrug R13（R13）是原肌球蛋白相关激酶B（TrkB）激活剂7,8-二羟基黄酮的前药形式。 | ||||
| GC91985 | Alloisolithocholic Acid-d4 | 2410277-60-8 | >99.00% | |
Alloisolithocholic Acid-d4用于GC-或LC-MS定量别异石胆酸的内标。 | ||||
| GC92004 | DPTIP (hydrochloride) | 2361799-64-4 | >95.00% | |
DPTIP (hydrochloride)是中性鞘磷脂酶2nMase2的抑制剂；IC50=30 nM。 | ||||
| GC92028 | UCM-05194 (ammonium salt) | - | >95.00% | |
UCM-05194 (ammonium salt)是溶血磷脂酸受体1 LPA1的激动剂。 | ||||
| GC92036 | MCL0020 (trifluoroacetate salt) | - | >98.00% | |
MCL0020 (trifluoroacetate salt)是一种黑素皮质素受体4mc4r拮抗剂。 | ||||
| GC92078 | PKG Inhibitor (trifluoroacetate salt) | - | >95.00% | |
PKG Inhibitor (trifluoroacetate salt)是一种特定的cGMP依赖性PKG抑制剂Ki=86μM。 | ||||
| GC92092 | CTX-1211 (trifluoroacetate salt) | - | >95.00% | |
CTX-1211 (trifluoroacetate salt)是黑皮质素受体的肽激动剂。 | ||||
| GC92095 | Ac-(D-Arg)-CEH-(D-Phe)-RWC-NH2 (trifluoroacetate salt) | - | >98.00% | |
Ac-(D-Arg)-CEH-(D-Phe)-RWC-NH2 (trifluoroacetate salt)是一种环肽和黑素皮质素受体4 （MC4R）的激动剂。 | ||||
| GC92097 | TCMCB07 (trifluoroacetate salt) | - | >98.00% | |
TCMCB07 (trifluoroacetate salt)是黑色素皮质素受体1 （MC1R）、MC3R、MC4R和MC5R的肽拮抗剂（ic50对人类受体分别为19.5、0.59、13.58和8.07 nM）。 | ||||
| GC92098 | HS-024 (trifluoroacetate salt) | - | >98.00% | |
HS-024 (trifluoroacetate salt)是黑皮质素受体4的环肽拮抗剂（MC4R；Ki=0.29nM）。 | ||||
| GC92099 | MSG606 (trifluoroacetate salt) | - | >95.00% | |
MSG606 (trifluoroacetate salt)是黑皮质素受体1的肽拮抗剂（MC1R；对人类受体的IC50=17 nM）和γ-黑素细胞刺激激素（γ-MSH）的衍生物。 | ||||
| GC92100 | Neuropeptide EI (rat) (trifluoroacetate salt) | - | >95.00% | |
Neuropeptide EI (rat) (trifluoroacetate salt)是大鼠前黑色素浓缩激素MCH的内源性肽片段，参与激素释放、梳理行为和运动活动。 | ||||
| GC92101 | γ1-MSH (human, mouse, rat, bovine) (trifluoroacetate salt) | - | >95.00% | |
γ1-MSH (human, mouse, rat, bovine) (trifluoroacetate salt)是一种肽激素，由垂体中的前皮黑皮质素（POMC）翻译后加工产生。 | ||||
| GC92102 | γ1-MSH (human, mouse, rat, bovine) (acetate) | - | >95.00% | |
γ1-MSH (human, mouse, rat, bovine) (acetate)是一种肽激素，由垂体中的前皮黑皮质素（POMC）翻译后加工产生。 | ||||
| GC92103 | HS-014 (trifluoroacetate salt) | - | >98.00% | |
HS-014 (trifluoroacetate salt)是黑素皮质素受体4mc4r的拮抗剂；Ki = 3.16 nM。 | ||||