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Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

研究方向

Neuroscience 相关产品(3932)

  • GC60938 structure
    GC60938Iprindole
    CAS: 5560-72-5
    纯度: >98.00%

    Iprindole具有抗抑郁的生物活性，是一种弱的去甲肾上腺素和5-HT摄取的抑制剂。

  • GC60939 structure
    GC60939Iproniazid
    CAS: 54-92-2
    纯度: >98.00%

    Iproniazid (Marsilid, Iprazid) is a non-selective, irreversible monoamine oxidase (MAO) inhibitor (MAOI) that is used as an antidepressive agent.

  • GC60957 structure
    GC60957Jatrorrhizine hydroxide
    CAS: 483-43-2
    纯度: >98.00%

    Jatrorrhizine (Neprotin, Yatrorizine), one of the active constituents of Coptis chinensis Franch, has multiple bioactivities, such as hypoglycemic, antimicrobial, and antioxidant activities. It is an inhibitor of AChE with IC50 of 872 nM and demonstrates >115-fold selectivity for AChE over BuChE.

  • GC60965 structure
    GC60965Keto Ziprasidone
    CAS: 884305-07-1

    KetoZiprasidone是Ziprasidone的杂质。Ziprasidone，一种抗精神药物，是5-HT和多巴胺(dopaminereceptor)受体拮抗剂。

  • GC60966 structure
    GC60966Ketorolac D5
    CAS: 1215767-66-0
    纯度: >98.00%

    An internal standard for the quantification of ketorolac

  • GC61017 structure
    GC61017Lycoramine hydrobromide
    CAS: 89505-76-0

    Lycoraminehydrobromide是一种从Lycorisradiate中分离出的加兰他敏的二氢衍生物。Lycoraminehydrobromide是一种有效的乙酰胆碱酯酶(AChE)抑制剂。

  • GC61038 structure
    GC61038Mefenamic acid D4
    CAS: 1216745-79-7

    An internal standard for the quantification of mefenamic acid

  • GC61067 structure
    GC61067Mirtazapine D3
    CAS: 1216678-68-0

    An Analytical Reference Material

  • GC61108 structure
    GC61108Naftidrofuryl oxalate
    CAS: 3200-06-4
    纯度: >95.00%

    Naftidrofuryloxalate(Nafronyloxalatesalt)是在外周血和脑血管病症如血管扩张药的管理中使用的药物,增加细胞氧化能力,且是一种5-HT2受体拮抗剂。

  • GC61162 structure
    GC61162Osthenol
    CAS: 484-14-0
    纯度: >98.50%

    Osthenol(Ostenol)是从独活干根中分离得到的一种前酰化香豆素，是一种可逆的，选择性的竞争性人单胺氧化酶-A(hMAO-A)抑制剂(Ki=0.26µM)。Osthenol对重组hMAO-A具有潜在的选择性抑制作用，IC50为0.74µM，对hMAO-A和hMAO-B表现出较高的选择性指数。

  • GC61167 structure
    GC61167Paliperidone palmitate
    CAS: 199739-10-1
    纯度: >98.00%

    Paliperidone Palmitate (9-hydroxyrisperidone palmitate) is a palmitate ester of paliperidone, which is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class.

  • GC61180 structure
    GC61180Phenidone
    CAS: 92-43-3
    纯度: >98.00%

    Phenidone (1-phenyl-3-pyrazolidinone), a dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), is an organic compound that is primarily used as a photographic developer.

  • GC61186 structure
    GC61186Picrotoxinin
    CAS: 17617-45-7
    纯度: >98.00%

    Picrotoxinin是一种来源于天然植物的苦味毒素，存在于一种名为 Anamirta cocculus 的攀援植物的种子中，是一种氯离子通道阻断剂。Picrotoxinin是一种非竞争性的GABA A 受体拮抗剂，负向调节神经递质γ氨基丁酸（GABA）对GABA A 受体的作用。

  • GC61193 structure
    GC61193Piroxicam D3
    CAS: 942047-64-5

    An internal standard for the quantification of piroxicam

  • GC61206 structure
    GC61206Profenofos
    CAS: 41198-08-7

    Profenofos是一种乙酰胆碱酯酶抑制有机磷农药，广泛应用于农田作物、蔬菜和水果作物。

  • GC61234 structure
    GC61234Rebamipide D4
    CAS: 1219409-06-9

    An internal standard for the quantification of rebamipide

  • GC61235 structure
    GC61235Regaloside B
    CAS: 114420-67-6

    RegalosideB是一种从Liliumlongiflorum中分离出来的苯丙烷。RegalosideB可以抑制iNOS和COX-2的表达，具有抗炎活性。

  • GC61238 structure
    GC61238Rehmapicrogenin
    CAS: 135447-39-1

    Rehmapicrogenin可从Rehmanniaglutinosa的根部分离得到，通过抑制iNOS、COX-2和IL-6表现出有效的抗炎作用。

  • GC61255 structure
    GC61255Rubrofusarin triglucoside
    CAS: 245724-07-6

    Rubrofusarintriglucoside是一种从决明子种子中分离得到的糖苷化合物，可抑制人单胺氧化酶A(hMAO-A)，IC50为85.5μM。

  • GC61256 structure
    GC61256Rupatadine D4 fumarate
    CAS: 1795153-63-7

    RupatadineD4fumarate(UR-12592D4fumarate)是Rupatadinefumarate的氘代标记物。RupatadineFumarate(UR-12592Fumarate)富马酸盐是PAF/H1受体双抑制剂，Ki值分别为0.55μM和0.1μM。

  • GC61268 structure
    GC61268SB 243213
    CAS: 200940-22-3
    纯度: >98.50%

    A 5-HT 2C receptor inverse agonist

  • GC61281 structure
    GC61281SKF-83566
    CAS: 99295-33-7
    纯度: >99.00%

    A dopamine D 1 receptor antagonist

  • GC61286 structure
    GC61286SP-8356
    CAS: 1454885-45-0
    纯度: >99.00%

    SP-8356, an anti-inflammatory synthetic verbenone derivative, is a CD147 inhibitor with respect to its regulation of breast cancer cell behavior and cancer progression.

  • GC61317 structure
    GC61317Tebanicline dihydrochloride
    CAS: 209326-19-2
    纯度: >98.50%

    Tebaniclinedihydrochloride(Ebaniclinedihydrochloride)是nAChR的调节物，具有有效的口服止痛活性。抑制cytisine与神经元nAChR的结合的Ki值为37pM。