GlpBio

Signaling Pathways

Signaling Pathways(信号通路)

研究方向

Signaling Pathways 相关产品(35130)

  • GC12196 structure
    GC12196AMD-070
    CAS: 558447-26-0

    A CXCR4 antagonist

  • GC12198 structure
    GC12198IEM 1754 dihydrobroMide
    CAS: 162831-31-4

    IEM 1754 dihydrobroMide 是一种双阳离子金刚烷衍生物，是天然离子型谷氨酸受体开放通道的有效阻断剂，包括昆虫肌肉中的 quisqualate 敏感受体、培养的大鼠皮质神经元中的 NMDAR 和新鲜分离的海马细胞中的 AMPAR。

  • GC12208 structure
    GC12208MLN8054
    CAS: 869363-13-3
    纯度: >99.00%

    An inhibitor of Aurora A kinase

  • GC12216 structure
    GC12216Axitinib (AG 013736)
    CAS: 319460-85-0
    纯度: >99.50% / >98.00%

    Axitinib (AG 013736)是一种具有口服活性的特异性血管内皮生长因子受体（VEGFR）抑制剂，主要靶向VEGFR-1、VEGFR-2和VEGFR-3，IC 50 值分别为 0.1nM、0.2nM和0.1-0.3nM。

  • GC12218 structure
    GC12218BIIB021
    CAS: 848695-25-0
    纯度: >99.50%

    A potent, orally-available Hsp90 inhibitor

  • GC12219 structure
    GC12219AR-M 1000390 hydrochloride
    CAS: 209808-47-9
    纯度: >99.50%

    AR-M 1000390 hydrochloride 是一种特别选择性的强效 δ 阿片受体激动剂，δ 激动剂效力的 EC50 为 7.2±0.9 nM。

  • GC12226 structure
    GC12226Cisatracurium Besylate
    CAS: 96946-42-8
    纯度: >98.00%

    A competitive antagonist of nAChRs and non-depolarizing muscle relaxant

  • GC12234 structure
    GC12234Dronedarone HCl
    CAS: 141625-93-6
    纯度: >99.50%

    An antiarrhythmic agent

  • GC12236 structure
    GC12236Daclatasvir dihydrochloride
    CAS: 1009119-65-6
    纯度: >99.50%

    An NS5A inhibitor

  • GC12241 structure
    GC12241NS 398
    CAS: 123653-11-2
    纯度: >98.50%

    A selective COX2 inhibitor

  • GC12248 structure
    GC12248Sapogenins Glycosides
    CAS: 8047-15-2
    纯度: >98.00% / >82.00%

    Sapogenins Glycosides (Saponin) 是一类在各种植物物种中特别丰富的糖苷化合物。

  • GC12249 structure
    GC12249Varlitinib (ARRY334543)
    CAS: 845272-21-1

    An inhibitor of EGFR and HER2

  • GC12254 structure
    GC12254Triamterene
    CAS: 396-01-0
    纯度: >99.50%

    An ENaC inhibitor

  • GC12257 structure
    GC12257Panobinostat (LBH589)
    CAS: 404950-80-7
    纯度: >99.00%

    Panobinostat (LBH589)是一种强效，且具有口服活性和抗肿瘤活性的广谱组蛋白去乙酰化酶（HDAC）抑制剂，IC 50 值为5nM。

  • GC12261 structure
    GC12261FRAX597
    CAS: 1286739-19-2
    纯度: >98.00%

    A PAK1, PAK2, and PAK3 inhibitor

  • GC12268 structure
    GC12268Mibefradil
    CAS: 116644-53-2
    纯度: >98.00%

    Mibefradil是一种钙通道阻断剂，可以阻断T型和L型钙通道，Mibefradil对T型和L型钙电流的IC 50 分别为0.7μM和2μM。

  • GC12269 structure
    GC12269Kanamycin Sulfate
    CAS: 25389-94-0
    纯度: BA-≥750u/mg

    Kanamycin Sulfate是一种广谱氨基糖苷类抗生素，对多种革兰氏阳性菌和革兰氏阴性菌具有强大的抗菌活性，包括多重耐药菌株。Kanamycin Sulfate在临床中常用于治疗严重感染。

  • GC12275 structure
    GC12275GSK2334470
    CAS: 1227911-45-6
    纯度: >99.50%

    A selective PDK1 inhibitor

  • GC12276 structure
    GC12276CGS 12066B dimaleate
    CAS: 109028-10-6
    纯度: >98.00%

    A 5-HT 1B receptor agonist

  • GC12278 structure
    GC12278Bedaquiline
    CAS: 843663-66-1
    纯度: >98.00%

    Bedaquiline是一种二芳基喹啉类抗结核药物。Bedaquiline可通过抑制结核分枝杆菌ATP合成酶来阻断细菌能量供应。

  • GC12280 structure
    GC12280PF-4981517
    CAS: 1390637-82-7
    纯度: >99.00%

    A potent, selective inhibitor of CYP3A4

  • GC12282 structure
    GC12282Tinidazole
    CAS: 19387-91-8
    纯度: >99.50%

    An antiparasitic and antimicrobial nitroimidazole

  • GC12283 structure
    GC12283Nicotine Difartrate
    CAS: 65-31-6
    纯度: >98.00% / ＞95.00%

    Nicotinic acetylcholine receptor (nAChR) agonist

  • GC12292 structure
    GC12292Ofloxacin
    CAS: 82419-36-1
    纯度: >99.50%

    A fluoroquinolone antibiotic