Signaling Pathways(信号通路)

Cat.No. 产品名称 Information

GC41345 (-)-α-Bisabolol

没药醇; (-)-α-Bisabolol

A sesquiterpene alcohol with diverse biological activities

GC40263 (-)-α-Cedrene

α-柏木烯; α-cedrene

A sesquiterpene

GC49502 (-)-β-Sesquiphellandrene

Β-倍半水芹烯

A sesquiterpene with antiviral and anticancer activities

GC45244 (-)-(α)-Kainic Acid (hydrate)

红藻氨酸

An L-glutamate analog with neuroexcitatory activities

GC31084 (-)-(S)-B-973B

(-)-(S)-B-973B为一种有效的α7nAChR别构激动剂和正别构调节剂，具有镇痛作用。

GC73658 (-)-5-HT2C agonist-3 (-)-5-HT2C agonist-3化合物-19是一种具有Gq信号偏好的5-HT2C选择性激动剂，5-HT2C的5-HT2受体的EC50值为103 nM；5-羟色胺2B：570 nM；5-HT2A:72nM。

GC14044 (-)-[3R,4S]-Chromanol 293B (-)-[3R,4S]-Chromanol 293B 是延迟整流器 K+ 电流 (IKs) 的慢速成分的有效选择性抑制剂。

GC32429 (-)-BAY-1251152

(-)-BAY-1251152; (-)-VIP152

A racemic mixture of (+)-BAY-1251152 and (–)-BAY-1251152

GC10065 (-)-Bicuculline methiodide

(-)-荷苞牡丹碱

GABAA受体拮抗剂

GC16857 (-)-Bicuculline methobromide

(-)-荷包牡丹碱甲溴化物,l-Bicuculline methobromide

(-)-Bicuculline methobromide (l-Bicuculline methobromide) 是一种有效的 GABAA 受体拮抗剂。

GC15636 (-)-Bicuculline methochloride

(-)-荷包牡丹碱甲氯化物,l-Bicuculline methochloride

An enantiomer of (+)-bicuculline methochloride

GC13430 (-)-Blebbistatin

(S)-(-)-Blebbistatin

(-)-Blebbistatin是外消旋体混合物(±)-Blebbistatin（货号：GC12341）的一种其中一个构型，是活性形式。(-)-Blebbistatin是一种非肌肉肌球蛋白II ATP酶的细胞渗透性抑制剂，有效抑制多种横纹肌肌球蛋白以及脊椎动物非肌肉肌球蛋白，IC₅₀值范围为0.5-5μM，平滑肌肌球蛋白仅受到微弱抑制（IC₅₀=80μM）。

GC61646 (-)-Camphoric acid

(-)-樟脑酸

(-)-Camphoricacid是Camphoricacid的低活性异构体。Camphoricacid刺激成骨细胞分化并诱导谷氨酸受体(glutamatereceptor)表达。Camphoricacid还诱导NF-κB和AP-1活化。

GC45245 (-)-Caryophyllene oxide

石竹素,(-)-Caryophyllene oxide

A bicyclic sesquiterpene

GC40842 (-)-Catechin

(-)-儿茶素; (-)-Cianidanol; (-)-Catechuic acid

A diastereoisomer of catechin

GC32957 (-)-Catechin gallate ((-)-Catechin 3-gallate)

儿茶素没食子酸酯; (-)-Catechin 3-gallate; (-)-Catechin 3-O-gallate

A polyphenol with diverse biological activities

GC30424 (-)-Cephaeline dihydrochloride (NSC 32944)

盐酸吐根酚碱,(-)-Cephaeline dihydrochloride; NSC 32944

(-)-Cephaeline dihydrochloride (NSC 32944) 是一种选择性 CYP2D6 抑制剂，IC50 为 121 μM.

GC45246 (-)-Chaetominine

(-)-Chaetominine

A cytotoxic alkaloid

GC71675 (-)-cis-Permethrin (-)-cis-Permethrin是一种菊酯类杀虫剂，广泛用于控制许多常见害虫。

GC30750 (-)-Corey lactone diol

科立内脂二醇

(-)-Coreylactonediol是coreyaldehyde的还原形式。化学合成中的砌块。

GC34947 (-)-Corynoxidine

延胡索乙素N氧化物

(-)-Corynoxidine 分离自延胡索 Corydalis speciosa，是一种乙酰胆碱酯酶 acetylcholinesterase 抑制剂，IC50 值为 89.0 μM。(-)-Corynoxidine 对金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌菌株有不同程度的抗菌活性。

GC17470 (-)-Cotinine

可替宁; (-)-Cotinine; (S)-Cotinine; NIH-10498

A major metabolite of nicotine

GC18343 (-)-CP 55,940

(-)-CP 55,940 is a potent and non-selective cannabinoid (CB) receptor agonist with Ki values of 0.5 to 5 and 0.69 to 2.8 nM for CB1 and CB2 receptors, respectively.

GC48635 (-)-Cryptopleurine

(R)-Cryptopleurine, NSC 19912

An alkaloid with diverse biological activities

GC45247 (-)-Cyclopenol

(-)-圆弧菌醇

A fungal metabolite

GC63940 (-)-Denudatin B

(-)-白玉兰亭B,Denudatin B

(-)-Denudatin B 具有抗血小板作用，通过电压门控和受体调控的Ca2+通道抑制Ca2+内流，从而放松血管平滑肌。(-)-Denudatin B 通过抑制胶原蛋白和凝血酶诱导的磷酸肌苷分解，在高浓度下具有非特异性的抗血小板作用。

GC32705 (-)-DHMEQ (Dehydroxymethylepoxyquinomicin)

Dehydroxymethylepoxyquinomicin

(-)-DHMEQ (Dehydroxymethylepoxyquinomicin) (Dehydroxymethylepoxyquinomicin) 是一种有效、选择性和不可逆的 NF-κB 抑制剂，可与半胱氨酸残基共价结合。

GC10603 (-)-epicatechin gallate

表儿茶素没食子酸酯; Epicatechin gallate; ECG; (-)-Epicatechin 3-O-gallate

A natural polyphenol with diverse protective actions

GC17242 (-)-epigallocatechin

(-)-表没食子儿茶素; Epigallocatechin; L-Epigallocatechin

A green tea polyphenol

GC14049 (-)-Epigallocatechin gallate (EGCG)

(-)-表没食子儿茶素没食子酸酯,EGCG

(-)-Epigallocatechin Gallate sulfate (EGCG) 是绿茶中的一种主要多酚,可抑制细胞增殖并诱导细胞凋亡。

GC40218 (-)-Epigallocatechin Gallate-d3/d4

EGCG-d3/d4

An internal standard for the quantification of (–)-epigallocatechin gallate

GC45248 (-)-FINO2 A ferroptosis inducer

GC46245 (-)-G-Lactone

(1S,5R)-2-氧杂二环[3.3.0]辛-6-烯-3-酮

A bicyclic γ-lactone

GC34948 (-)-GSK598809

1S,5R-GSK598809

(-)-GSK598809 是GSK598809的异构体。GSK598809 是多巴胺 D3 受体 (DRD3) 的选择性拮抗剂。

GC69463 (-)-GSK598809 hydrochloride

(1S,5R)-GSK598809 hydrochloride

(-)-GSK598809 是 GSK598809 的异构体。GSK598809 是多巴胺 D3 受体 (DRD3) 的选择性拮抗剂。

GC41344 (-)-Guaiol

(-)-愈创醇; Champacol; Guaiac alcohol

A sesquiterpene alcohol with diverse biological activities

GC14400 (-)-Huperzine A

石杉碱甲; Huperzine A

A neuroprotective AChE inhibitor

GC71452 (-)-Hydroxycitric acid (-)-Hydroxycitric acid藤黄酸是藤黄果皮的主要酸。

GC63570 (-)-Hydroxycitric acid lactone

藤黄内酯,Garcinia lactone

(-)-Hydroxycitric acid lactone (Garcinia lactone) 是一种减肥药，也是一种很受欢迎的减肥食品补充剂。(-)-Hydroxycitric acid lactone 是一种有效的 ATP-柠檬酸裂解酶抑制剂。(-)-Hydroxycitric acid lactone 催化柠檬酸盐线粒体外裂解为草酰乙酸和乙酰辅酶 A，限制了脂肪酸合成所需乙酰辅酶 A 单位的可用性。