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HSV-8 M

目录号 : GP25215

Herpes Simplex Virus-8 Mosaic Recombinant

Description

The E.Coli derived recombinant protein contains the C-terminal immunodominant regions from ORF65 140-170 a.a. and N-terminal regions from ORF8 32-62 a.a. The protein is fused with a GST tag.

Product Data

Purity HSV-8 Mosaic protein is >95% pure as determined by 10% PAGE (coomassie staining). Source
Phycical Appearance Sterile Filtered clear solution. Shipping Condition Shipped with Ice Packs.
Stability HSV-8 Mosaic protein although stable at 4°C for 1 week, should be stored below -18°C .Please prevent freeze thaw cycles.
Formulation 100mM NaCl, 0.1% SDS and 50% glycerol.

Introduction

Entry of HSV into the host cell involves interactions of several viral glycoproteins with cell surface receptors. The virus particle is covered by an envelope which, when bound to specific receptors on the cell surface, will fuse with the cell membrane and create an opening, or pore, through which the virus enters the host cell. The sequential stages of HSV entry are analagous to those of other viruses. At first, complementary receptors on the virus and cell surface bring the two membranes into proximity. In an intermediate state, the two membranes begin to merge, forming a hemifusion state. Finally, a stable entry pore is formed through which the viral envelope contents are introduced to the host cell.

Purification Method

HSV-8 Mosaic was purified by proprietary chromatographic technique.

Applications

HSV-8 Mosaic antigen is suitable for ELISA and Western blots, excellent antigen for detection of HSV with minimal specificity problems.

Stability

HSV-8 Mosaic protein although stable at 4°C for 1 week, should be stored below -18°C .Please prevent freeze thaw cycles.

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