Cell Cycle/Checkpoint(细胞周期/检查点)

Cell Cycle

Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more

Products for Cell Cycle/Checkpoint

Cat.No. 产品名称 Information
GC44260 Myristoyl Coenzyme A (hydrate)

Myristoyl-CoA, Tetradecanoyl Coenzyme A, Tetradecanoyl-CoA

A substrate for N-myristoyltransferase
GC45958 Myrothecine A A trichothecene mycotoxin
GC49491 N′-Nitrosonornicotine-d4

氘代N-亚硝基降烟碱(NNN)
An internal standard for the quantification of N'-nitrosonornicotine
GC49163 N’-Nitrosonornicotine

N-亚硝基降烟碱(NNN)
An N-nitrosamine and a carcinogen
GC45531 N-α-Benzoyl-L-Arginine ethyl ester (hydrochloride)

BAEE, Bz-Arg-OEt, NSC 86159
A nonpeptide substrate of proteases and deiminases
GC45667 N-(p-Tosyl)-GPR-pNA (acetate)

N-对甲苯磺酰基-甘氨酰-脯氨酰-精氨酰对硝基苯胺
A colorimetric thrombin substrate
GC18445 N-Deacetylcolchicine

NSC 201400
An inhibitor of microtubule polymerization
GC44343 n-Decyl-β-D-maltoside

n-Decyl-β-D-maltopyranoside, Decyl-β-maltopyranoside, Decyl-β-maltoside, Decylmaltoside
A nonionic surfactant
GC52007 N-hydroxylamine Dapsone

羟胺氨苯砜
An active metabolite of dapsone
GC49351 N-Nitroso Atenolol

NO-Atenolol
A genotoxic derivative of (±)-atenolol
GC49394 N-Nitroso Fluoxetine

氟西汀杂质22
A derivative of fluoxetine
GC49353 N-Nitroso Metoprolol A genotoxic derivative of metoprolol
GC44430 n-Nonyl-β-D-glucopyranoside

壬基-Β-D-葡萄吡喃糖甙
An anionic chiral surfactant
GC45833 N-Oleoyl-L-phenylalanine

18-1-Phe, C18:1-Phe
An N-acyl amide
GC47806 N-p-Tosyl-Gly-Pro-Lys-pNA (acetate)

N-p-Tosyl-Gly-Pro-Lys-p-nitroanilide
A colorimetric plasmin substrate
GC44313 Naphthofluorescein

萘基荧光素,Naphthafluorescein
Inhibitor of furin
GC12491 Narciclasine

水仙环素; Lycoricidinol
A plant growth regulator with anticancer activity
GC70777 NBI-42902 NBI-42902是一种口服活性、强效功能性和竞争性GnRH受体拮抗剂，IC50值分别为0.79 nM和0.56 nM。
GC73643 NBI-961 NBI-961是一种有效的NEK2抑制剂，可抑制蛋白酶体降解。
GC49204 Nefazodone-d6 (hydrochloride)

BMY-13754-d6; MJ-13754-1-d6
An internal standard for the quantification of nefazodone
GC90669 Negamycin (hydrochloride)

(+) Negamycin

一种抗生素。
GC45523 Nemorosone A PPAP with antiproliferative properties
GC10716 Netarsudil (AR-13324)

2,4-二甲基苯甲酸[4-[(1S)-1-(氨基甲基)-2-(6-异喹啉基氨基)-2-氧代乙基]苯基]甲基酯二盐酸盐
ROCK抑制剂
GC74069 NH2-PEG3-VC-PAB-MMAE NH2-PEG3-VC-PAB-MMAE是ADC的药物连接物偶联物，由可切割的ADC连接物（NH2-PEG3-VC-PAB）和有效的微管蛋白抑制剂Monometl auristatin E （MMAE）组成。
GC12515 NMS-1286937

4,5-二氢-1-(2-羟基乙基)-8-[[5-(4-甲基-1-哌嗪基)-2-(三氟甲氧基)苯基]氨基]-1H-吡唑并[4,3-H]喹唑啉-3-甲酰胺,NMS-1286937; NMS-P937
An inhibitor of Plk1
GC36752 NMS-P715 An Mps1/TTK inhibitor
GC14075 Nocodazole

诺考达唑
Nocodazole是一种抗有丝分裂药物，是一种快速可逆的微管聚合抑制剂，在无细胞试验中抑制Abl，Abl（E255K）和Abl（T315I），IC₅₀值分别为0.21μM，0.53μM和0.64μM。
GC47803 Noscapine-13C-d3

Narcotine-13C-d3, Opianine-13C-d3
An internal standard for the quantification of noscapine
GC44464 NSC 109555

DDUG, NCI C04808
An inhibitor of Chk2
GC13448 NSC 109555 ditosylate An inhibitor of Chk2
GC46190 NSC 15520 An inhibitor of RPA70 dsDNA binding
GC10069 NSC 23766 trihydrochloride Inhibitor of Rac1
GC12886 NSC 625987

Cdk4 Inhibitor II
A Cdk4/cyclin D1 complex inhibitor
GC11634 NSC 693868

1H-吡唑并[3,4-B]喹喔啉-3-胺,Cdk1/5 Inhibitor
A selective inhibitor of Cdk1 and Cdk5
GC49412 NSC 756093 An inhibitor of the GBP1-Pim-1 protein-protein interaction
GC15963 Nu 6027 A CDK and ATR inhibitor
GC18278 NU 6102

4-[[6-(环己基甲氧基)-1H-嘌呤-2-基]氨基]苯磺酰胺
A potent Cdk1 and Cdk2 inhibitor
GC34692 NU6140 A Cdk2 inhibitor
GC44475 NVP-BEZ235 (hydrochloride)

Dactolisib
Dual inhibitor of PI3K and mTOR
GC16959 NVP-LCQ195

4-(2,6-二氯苯甲酰基氨基)-1H-吡唑-3-羧酸N-[1-(甲基磺酰基)哌啶-4-基]酰胺,LCQ-195;AT-9311;NVP LCQ195;LCQ 195;AT9311;AT 9311
NVP-LCQ195 (AT9311; LCQ195) 是 CDK1、CDK2、CDK3 和 CDK5 的小分子杂环抑制剂，IC50 为 1-42 nM。
GC32830 NVS-PAK1-1 An allosteric inhibitor of PAK1
GC44478 NVS-PAK1-C A negative control for NVS-PAK1-1
GC61870 NY2267 NY2267 是一种 Myc-Max 相互作用 (Myc-Max interaction) 干扰物，其 IC50 值为 36.5 µM。
GC49186 O-Demethyl Apremilast

阿普斯特杂质
An active metabolite of apremilast
GC18727 O-methyl Sterigmatocystin

O-甲基杂色曲霉素
An aflatoxin precursor
GC72054 Obovatol Obovatol是一种从厚朴叶中分离出来的联苯醚木脂素。
GC47814 Ochratoxin A-13C20

赭曲霉素A13C20溶液
An internal standard for the quantification of ochratoxin A
GC44495 OH-C-Chol A cationic cholesterol
GC45534 OH-Chol A cationic cholesterol derivative
GC16520 Olomoucine

2-(2'-羟基乙基氨基)-9-甲基-6-(苄基氨基)嘌呤
An inhibitor of cyclin-dependent kinases