Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC50198 Topiramate - d12

托吡酯-D12,McN 4853 D12 ; RWJ 17021 D12
An internal standard for the quantification of topiramate
GC31220 Toreforant (JNJ-38518168)

JNJ-38518168
Toreforant (JNJ-38518168) 是一种有效的选择性组胺 H4 受体 (H4R) 拮抗剂，对人受体的 Ki 值为 8.4 nM。
GC40043 Totarol

桃柁酚,NSC 299936, (+)-Totarol, trans-Totarol
A diterpene with diverse biological activities
GC30865 TPA 023 TPA023是GABAAα2/α3的选择性的激动剂，Ki值为0.19-0.41nM。
GC67996 TPA-023B TPA-023B 是一种高亲和力的口服活性的 GABAA 受体 α2/α3 亚型 (Ki 为 0.73 nM/2 nM) 部分激动剂和 α1 亚型 (Ki 为 1.8 nM) 拮抗剂。TPA-023B 具有非镇静抗焦虑特性。
GC48191 TPMPA (hydrate) 选择性 GABA\u003csub\u003eA\u003c/sub\u003e-ρ1 (ρ1 GABA\u003csub\u003eC\u003c/sub\u003e) 受体拮抗剂
GC13346 TQS TQS 是一种 α7 烟碱型乙酰胆碱受体 (nAChR) 正变构调节剂。
GC33735 Tradipitant (VLY-686)

VLY-686; LY686017
Tradipitant (VLY-686) (VLY-686) 是一种神经激肽-1 (NK-1) 拮抗剂。
GC17910 Tramiprosate

3-氨基丙烷磺酸; Homotaurine; 3-Amino-1-propanesulfonic acid
A sulfated glycosaminoglycan mimetic
GC65582 Tramiprosate-d6

3-丙基甲苯,Homotaurine-d6; 3-Amino-1-propanesulfonic acid-d6
Tramiprosate-d6 (Homotaurine-d6) 是 Tramiprosate 的氘代物。Tramiprosate (Homotaurine)，一种具有口服活性和可透过血脑屏障的天然氨基酸，存在于各种红色海藻中。Tramiprosate 与可溶性 Aβ 结合并以非原纤维形式维持 Aβ。Tramiprosate 还是一种 GABA 类似物，具有神经保护，抗惊厥和抗高血压的作用。
GC20062 trans-3'-Hydroxycotinine

3'R,5'S)-3'-羟基可替宁,3HC
A metabolite of nicotine
GC45070 trans-Clovamide

trans-Clovamide
An antioxidant
GC13266 trans-Triprolidine hydrochloride

盐酸曲普利啶
trans-Triprolidine hydrochloride 是一种具有口服活性的组胺 H1 拮抗剂。
GC33341 Transcrocetin (trans-Crocetin)

藏红花酸; trans-Crocetin
A natural apocarotenoid with diverse biological activities
GC37821 Transcrocetin meglumine salt

trans-Crocetin meglumine salt
A natural apocarotenoid with diverse biological activities
GC32447 Transcrocetinate disodium (Disodium trans-crocetinate)

藏红花酸二钠盐,Disodium trans-crocetinate
从藏红花 (Crocus sativus L.) 中提取的 Transcrocetinate disodium (Disodium trans-crocetinate) 作为 NMDA 受体拮抗剂具有高亲和力。
GC30766 Tranylcypromine hemisulfate (dl-Tranylcypromine hemisulfate)

反苯环丙胺半硫酸盐; SKF 385 hemisulfate
Tranylcypromine (Parnate) is an irreversible inhibitor of monoamine oxidase (MAO) with a rapid onset of activity.
GC30839 Traxoprodil

曲索罗地

An antagonist of NR2B subunit-containing NMDA receptors
GC26002 Trazodone

AF-1161
Trazodone (AF-1161) is a 5-HT 2A/2C receptor antagonist that is used as an antidepressant for treating major depressive disorder and anxiety disorders.
GC14927 Trazodone HCl

盐酸曲唑酮; AF-1161
An Analytical Reference Material
GC45584 Triamcinolone acetonide-d7 An internal standard for the quantification of triamcinolone acetonide
GC52005 Triazolomethylindole-3-acetic Acid

三唑甲基吲哚-3-乙酸
A metabolite of rizatriptan
GC49247 Triazolopyridinone

吡啶三唑酮
An intermediate in the synthesis of trazadone
GC70059 Tribendimidine

三苯双脒
Tribendimidine 一种广谱的、具有口服活性的驱虫剂，对 A. lumbricoides 和 N. americanus 具有特别高的活性。Tribendimidine 也是 L 型烟碱乙酰胆碱受体 (nAChR) 激动剂。
GC45085 Trientine (hydrochloride)

盐酸三乙烯四胺,Triethylenetetramine
A polyamine chelating agent
GC63240 Trifluoperazine

三氟拉嗪
Trifluoperazine (TFP)是一种多巴胺受体拮抗剂，具有抗精神病作用，广泛用于治疗精神分裂症或相关精神病。
GC13031 Trifluoperazine 2HCl

盐酸三氟拉嗪；甲哌氟丙嗪；三氟吡拉嗪
An anti-adrenergic and anti-dopaminergic agent
GC49217 Trifluoperazine N-Glucuronide

三氟拉嗪N-Β-D-葡糖苷酸,UGT1A4
A metabolite of trifluoperazine
GC48204 Trifluoperazine-d3 (hydrochloride)

三氟拉嗪-D3盐酸盐
An internal standard for the quantification of trifluoperazine
GC30790 Triflupromazine hydrochloride

盐酸三氟丙嗪
A phenothiazine with diverse biological activities
GC13300 Triflusal

三氟柳
An inhibitor of platelet aggregation
GC12311 Trihexyphenidyl hydrochloride

盐酸苯海索
A muscarinic M₁ receptor antagonist
GC45945 Trihydroxycholestanoic Acid

粪甾烷酸,Trihydroxycoprostanic Acid
A cholic acid intermediate
GC33527 Trimethobenzamide hydrochloride (Ro 2-9578)

盐酸三甲氧苯酰胺,Ro 2-9578
A dopamine D₂ receptor antagonist and antiemetic
GC17488 Trimipramine (maleate)

三甲丙咪嗪马来酸盐
A tricyclic antidepressant
GC52060 Trimipramine N-oxide

10,11-二氢-N,N,BETA-三甲基-5H-二苯并[B,F]氮杂卓-5-丙胺N-氧化物
An active metabolite of trimipramine
GC48550 Trimipramine-d3 (maleate)

马来酸三甲丙咪嗪 d3 (马来酸盐)
An internal standard for the quantification of trimipramine by GC- or LC-MS
GC12061 Tripelennamine HCl

盐酸吡苄明；去敏灵；扑敏宁；盐酸吡甲胺；盐酸吡苯胺
Tripelennamine HCl 是一种乙二胺衍生物，是一种有效的组胺 H1 受体拮抗剂。
GC39735 Triprolidine hydrochloride monohydrate

盐酸曲普利啶一水合物
Triprolidine Hydrochloride is the hydrochloride salt form of Triprolidine, which is the first generation histamine H1 antagonist used in allergic rhinitis.
GC91977 TrkB Agonist Prodrug R13

TrkB-IN-1; Tropomyosin-related Kinase B Agonist Prodrug R13; Tropomyosin-related Kinase B Inhibitor 1
TrkB Agonist Prodrug R13（R13）是原肌球蛋白相关激酶B（TrkB）激活剂7,8-二羟基黄酮的前药形式。
GC90929 Trofinetide (acetate)

NNZ-2566

一种由甘-脯-谷氨酸衍生的化合物。
GC74629 Trontinemab

RG6102; RO-7126209
Trontinemab（RG6102）是一种脑渗透性、抗淀粉样蛋白、双特异性和人源化IgG1-κ抗体，靶向aβ斑块和转铁蛋白受体1（TFR1）。
GC15150 Tropicamide

托吡卡胺; Ro 1-7683
A selective muscarinic M₄ antagonist
GC71641 Tropicamide-d3 Tropicamide-d3是氘标记的托吡卡胺。
GC15223 Tropisetron Hydrochloride

盐酸托烷司琼
A 5-HT₃ receptor antagonist
GC48208 Tropisetron-d5 A neuropeptide with diverse biological activities
GC17483 Trospium chloride

曲司氯铵
An antagonist of muscarinic receptors
GC40027 True Blue

NCI 240899
A fluorescent neuronal retrograde tracer
GC70071 TRV-7019 TRV-7019 是一种可穿透大脑屏障的放射性配体，可用于靶向丁酰胆碱酯酶的脑成像。TRV-7019 可用于诊断淀粉样蛋白病、多发性硬化症、脑肿瘤或丁酰胆碱酯酶活性。
GC48930 Tryptamine-d4 (hydrochloride)

D4色胺盐酸
An internal standard for the quantification of tryptamine