Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC45045 Thioperamide (maleate)

硫丙咪胺马来酸,MR-12842 maleate
A histamine H₃ receptor antagonist
GC11977 Thioridazine HCl

盐酸硫利达嗪；盐酸硫代利哒；甲硫达嗪盐酸盐；甲硫哒嗪盐酸盐
A typical antipsychotic
GC48173 Thioridazine-d3 (hydrochloride)

盐酸氟西汀杂质-d3
An internal standard for the quantification of thioridazine
GC48174 Thiorphan-d5 An internal standard for the quantification of thiorphan
GC18797 Thiothixene

氨砜噻吨
A typical antipsychotic
GC37784 THIP

加波沙朵,Gaboxadol
THIP (Gaboxadol) 是一种选择性 δ-GABAAR 激动剂，功能选择性 GABAAR 配体，对 α4β1δ, α4β3δ 表现出激动作用，对 αβγ 和 α4β2δ GABAARs 表现出弱拮抗作用。
GC25994 Thonzylamine

Neohetramine
Thonzylamine (Neohetramine) is an antihistamine and anticholinergic drug.
GC17047 Threo-methylphenidate hydrochloride

盐酸哌甲酯

盐酸苏哌甲酯(Threo-methylphenidate hydrochloride)是一种儿茶酚胺再摄取抑制剂,抑制多巴胺转运蛋白(DAT)和去甲肾上腺素转运蛋白(NET)。
GC45750 Thymosin β4 (human, mouse, rat, porcine, bovine) (acetate)

Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES-NH2
An actin-sequestering peptide
GC48358 Thymulin (acetate hydrate)

Thymic Factor
A peptide hormone
GC10186 Tiagabine

噻加宾
A GAT-1 inhibitor
GC17402 Tiagabine hydrochloride

盐酸噻加宾; NO050328 hydrochloride; NO328 hydrochloride; TGB hydrochloride
A GAT-1 inhibitor
GC37788 Tiagabine hydrochloride hydrate

噻加宾盐酸水合物; NO050328 hydrochloride hydrate; NO328 hydrochloride hydrate; TGB hydrochloride hydrate
A GAT-1 inhibitor
GC48178 Tiagabine-d6 (hydrochloride) An internal standard for the quantification of tiagabine
GC14788 Tianeptine

噻奈普汀
An atypical antidepressant
GC10121 Tianeptine sodium

噻奈普汀钠
An atypical antidepressant
GC49905 Tianeptine-d6 (hydrochloride) An internal standard for the quantification of tianeptine
GC30975 Tiapride hydrochloride

盐酸硫必利
Tiapride is a drug that selectively blocks D2 and D3 dopamine receptors in the brain and is used to treat a variety of neurological and psychiatric disorders.
GC45579 Tiaprofenic Acid

噻洛芬酸
A COX inhibitor and NSAID
GC48790 Ticlopidine-d4 (hydrochloride)

盐酸噻氯匹定 d4 (盐酸盐)
An internal standard for the quantification of ticlopidine
GC31956 Tilmacoxib (JTE522)

替马考昔; JTE522; JTP19605; RWJ57504
Tilmacoxib (JTE522) (JTE522) 是一种高度选择性、时间依赖性和不可逆的人 COX-2 抑制剂，在酶试验中 IC50 为 85 nM。
GC71047 TIM-063 TIM-063CaMKKα和CaMKKβ的Ki值分别为0.35μM和0.2μM，IC50值分别为0.63μM和0.96μM。
GC31965 Timegadine (SR1368)

替美加定; SR1368
Timegadine (SR1368) 是一种新型抗炎剂，被发现是一种有效的、竞争性的环加氧酶 (COX) 和脂加氧酶抑制剂，IC50 范围为 5 nM（洗涤过的兔血小板）至 20 μM（大鼠脑） ) 用于 COX 和 100 μ；M 用于马血小板匀浆的胞质溶胶部分和洗涤过的兔血小板中的脂加氧酶。
GC32666 Timepidium bromide (Sesden)

噻哌溴铵,Sesden; SA504
Timepidium bromide (Sesden) (Sesden; SA504) 是一种抗胆碱能药物。
GN10616 Timosaponin A3

知母皂苷A-III,Xilingsaponin A; Zhi-mu saponin
A natural steroid saponin
GC11330 Tiotidine

硫替丁,ICI 125211
Tiotidine (ICI 125211) 是一种有效的选择性组胺 H2 受体拮抗剂（豚鼠右心房的 pA2=7.3-7.8）。
GC12554 Tiotropium Bromide

噻托溴铵; BA679 BR
A muscarinic receptor antagonist
GC13134 Tiotropium Bromide hydrate

噻托溴铵一水合物,BA-679 BR (hydrate)
A muscarinic receptor antagonist
GC71660 Tiotropium bromide monohydrate Tiotropium bromide monohydrate是一种抗胆碱能和支气管扩张剂，也是毒蕈碱受体拮抗剂。
GC72979 Tisolagiline

KDS2010
Tisolagiline（KDS2010）是一种可逆的MAO-B抑制剂，用于帕金森病研究。
GC48183 Tizanidine-d4 (hydrochloride) An internal standard for the quantification of tizanidine
GC19438 TMB 8 (hydrochloride)

3,4,5-三甲氧基苯甲酸(8-二乙氨基正辛基)酯盐酸盐
A non-competitive antagonist of nAChRs and an inhibitor of intracellular calcium availability
GC63230 TML-6 TML-6 是一种口服有效的姜黄素衍生物，抑制 β-淀粉样前体蛋白和 β-淀粉样蛋白 (Aβ) 的合成。TML-6 上调 Apo E，抑制 NF-κB 和 mTOR，并增加抗氧化 Nrf2 基因的活性。TML-6 具有用于阿尔茨海默氏病 (AD) 研究的潜力。
GC11406 TMPH hydrochloride neuronal nicotinic ACh receptors (nAChRs) antagonist
GC65328 TNIK-IN-3 TNIK-IN-3 (化合物 21k) 是一种有效，选择性和具有口服活性的 TNIK 抑制剂，IC50 值为 0.026 μM。TNIK-IN-3 还可以抑制 Flt4 (IC50=0.030 μM)，Flt1 (IC50=0.191 μM) 和 DRAK1 (IC50=0.411 μM)。TNIK-IN-3 可用于结直肠癌的研究。
GC90884 TNP-ATP (sodium salt)
这是一种ATP衍生物，可以作为嘌呤能受体P2Y1、P2X3和P2X2/3的拮抗剂。
GC17921 Tolcapone

托卡朋; Ro 40-7592
A reversible COMT inhibitor
GC45763 Tolcapone-d4

托卡朋-D4,Ro 40-7592-d4
An internal standard for the quantification of tolcapone
GC15395 Tolfenamic Acid

托芬那酸; GEA 6414
An NSAID with anticancer activity
GC45965 Tolfenamic Acid-d4

托芬那酸 D4
An internal standard for the quantification of tolfenamic acid
GC61337 Tolmetin

托麦汀；托美丁
Tolmetin (Tolectin) is a nonsteroidal anti-inflammatory drug of the heterocyclic acetic acid derivative class and also exhibits analgesic and antipyretic activity.
GC16428 Tolmetin (sodium salt hydrate)

痛灭定
A non-selective NSAID
GC34842 Toloxatone

托洛沙酮; MD 69276

An inhibitor of MAO-A
GC48185 Tolperisone-d10 (hydrochloride)

盐酸托哌酮 d10 (盐酸盐)
An internal standard for the quantification of tolperisone
GC52262 Tolterodine Dimer A potential impurity in commercial preparations of tolterodine
GC17954 Tolterodine tartrate

酒石酸托特罗定,Kabi-2234; PNU-200583E
A muscarinic acetylcholine receptor antagonist
GC71594 Tolterodine-d14 hydrochloride Tolterodine-d14 hydrochloride是氘标记的盐酸托特罗定。
GC50192 Tomoxetine - d3 hydrochloride

盐酸阿托西汀-d3
An internal standard for the quantification of atomoxetine
GC16494 Tonabersat

SB-220453;SB 220453;SB220453
An anti-migraine agent
GC16149 Topiramate

托吡酯; McN 4853; RWJ 17021
An anticonvulsant