Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC40401 Prostaglandin F2α Alcohol methyl ether

AGN 191129, PGF2αOMe
A PGF_2α analog
GC41407 Prostaglandin F2α Ethanolamide

Dinoprost Ethanolamide, PGF2αEA
A metabolite of AEA
GC47998 Prostaglandin F2α Ethanolamide-d4

Dinoprost Ethanolamided4, PGF2αEAd4
A neuropeptide with diverse biological activities
GC44723 Prostaglandin F2α ethyl amide

Dinoprost ethyl amide, PGF2αNEt
An ocular hypotensive prodrug
GC44724 Prostaglandin F2α isopropyl ester

Dinoprost isopropyl ester, PGF2α isopropyl ester
An ester prodrug of PGF_2α
GC18914 Prostaglandin F2α Alcohol

AGN 190190, PGF2αOH, ZK 62717
A PGF_2α analog
GC18370 Prostaglandin F2α methyl ester

地诺前列素甲酯
A PGF_2α analog with ocular hypotensive activity
GC49873 Protectin D1 methyl ester

Neuroprotectin D1 methyl ester, NPD1 methyl ester, PD1 methyl ester
An esterified form of protectin D1
GC44732 Protopine (hydrochloride)

盐酸前鸦片碱
An alkaloid with diverse biological activities
GC30856 Protriptyline hydrochloride

盐酸普罗替林

A tricyclic antidepressant
GC15957 Proxyfan oxalate 组胺H3受体配体
GC91488 Proxymetacaine (hydrochloride)

Proparacaine
Proxymetacaine is an anesthetic.
GC11714 Prucalopride

普芦卡必利
A selective 5-HT₄ receptor agonist
GC13291 Prucalopride Succinat

琥珀酸普芦卡必利; R-108512
A selective 5-HT₄ receptor agonist
GC72789 Pruvanserin

EMD 281014 free acid; LY 2422347
Pruvanserin（EMD 281014游离酸）是一种选择性5-HT2A受体拮抗剂。
GC50564 PRX 07034

5-氯-2,3-二甲氧基-Α-甲基-N-[2-(甲基磺酰基)-5-(1-哌嗪基)苯基]-苯甲胺盐酸盐
PRX 07034 是一种高度选择性和有效的 5-HT6 受体拮抗剂，Ki = 4-8 nM，IC50 为 19 nM。
GC10450 PRX-08066 A 5-HT_2B receptor antagonist
GC16788 PRX-08066 Maleic acid 5-HT2B receptor antagonist,potent and selective
GC32595 PRX933 hydrochloride (GW876167 hydrochloride)

GW876167 hydrochloride; BVT-933 hydrochloride
PRX933 hydrochloride (GW876167 hydrochloride) 是一种 5-HT2c 受体激动剂，提取自专利 WO 2014140631 A1。
GC39141 Pseudocoptisine acetate

异黄连碱乙酸盐; Isocoptisine acetate
Pseudocoptisine acetate，一种具有苄基异喹啉骨架的季生物碱，分离于 Corydalis turtschaninovii 的块茎中。 Pseudocoptisine acetat 显示抗炎特性。
GC61566 Pseudocoptisine chloride

盐酸异黄连碱; Isocoptisine chloride
Pseudocoptisine chloride (Isocoptisine chloride) is a quaternary alkaloid with benzylisoquinoline skeleton isolated from Corydalis Tuber, inhibits acetylcholinesterase (AChE) activity with an IC50 of 12.8 μM, showing anti-inflammatory and anti-amnestic effects.
GC48406 PSI (trifluoroacetate salt)

Proteasome Inhibitor I, Z-Ile-Glu(OtBu)-Ala-Leu-aldehyde, Z-Ile-Glu(OtBu)-Ala-Leu-CHO
A proteasome inhibitor
GC64646 Psoralenoside

补骨脂苷
Psoralenoside 是源于 Psoralea corylifolia 中的一种苯并呋喃苷。Psoralenoside 对组胺 H1、钙调素和电压门控 l 型钙通道 (E-value≥-6.5 Kcal/mol) 具有较高的亲和力。Psoralenoside 具有雌激素样活性、促进成骨细胞增殖活性、抗肿瘤活性和抗菌活性。
GC14847 Psoralidin

补骨脂定
A furanocoumarin with anti-cancer activity
GC48356 Psychotridine An alkaloid with diverse biological activities
GC14508 PTAC oxalate muscarinic receptor ligand
GC60311 PTUPB PTUPB是一种新型的COX-2和sEH双抑制剂，IC₅₀ 值分别为 1.26 nM 和 0.9μM。
GN10680 Puerarin

葛根素
A natural isoflavonoid
GC31393 Pumosetrag Hydrochloride (MKC-733)

7-氧代-N-[3(R)-奎宁环基]-4,7-二氢噻吩并[3,2-B]吡啶-6-甲酰胺盐酸盐,MKC-733; DDP-733
Pumoserag Hydrochloride (MKC-733) (MKC-733; DDP-733) 是一种口服 5-HT3 部分激动剂，用于治疗肠易激综合征和胃食管反流病。
GC52484 Purified Ganglioside Mixture (bovine) (ammonium salt) A mixture of purified bovine gangliosides
GC63157 PW0464

PW0464
PW0464 是一种纳摩尔有效的完全 G 蛋白偏向配体，是一种非儿茶酚 D1R 激动剂，EC50 为 5.8 nM (Gs-cAMP)。
GC62202 PXS-4728A

BI-1467335
PXS-4728A 是一种具有口服活性的选择性氨基脲敏感性胺氧化酶 (SSAO) 抑制剂。PXS-4728A 可改善小鼠的慢性阻塞性肺疾病。
GC63158 PXS-5120A PXS-5120A 是一种有效的，不可逆的 Lysyl Oxidase-like 2/3 (LOXL2/3) 的氟代烯丙胺抑制剂，具有抗纤维化活性。与 LOXL (pIC50 为 5.8) 相比，PXS-5120A 对 LOXL2 (Ki 为 83 nM; pIC50 为 8.4) 的选择性高 300 倍以上。
GC31890 PXS-5153A
PXS-5153A是一种有效的、选择性的、具有口服活性和快速起效的赖氨酰氧化酶2/3(LOXL2/LOXL3)的双抑制剂，对几乎所有哺乳动物LOXL2的IC50均<40nM，对人类LOXL3的IC50为63nM。PXS-5153A可减少交联，改善纤维化。
GC38583 PXS-5153A monohydrochloride PXS-5153A monohydrochloride 是一种有效的、选择性的、具有口服活性和快速起效的赖氨酰氧化酶 2/3 (LOXL2/LOXL3) 的双抑制剂，对几乎所有哺乳动物LOXL2的IC50 均< 40 nM，对人类LOXL3 的IC50 为63 nM。PXS-5153A monohydrochloride 可减少交联，改善纤维化。
GC48013 PYD-106 A positive allosteric modulator of NR2C subunit-containing NMDARs
GC15348 Pyridostigmine Bromide

溴化吡啶斯的明
An inhibitor of AChE and BChE
GC34288 Pyridostigmine D6 bromide

溴化吡啶斯的明 d6 (溴盐)
PyridostigmineD6bromide是Pyridostigmine的氘代化合物标准品。
GC44790 Pyrithiamine (hydrobromide)

抗硫胺氢溴酸
Pyrithiamine (hydrobromide)是一种硫胺素类似物，可抑制硫胺素（维生素B1）的代谢。
GC50375 PZ-II-029 α6β3γ2-selective GABAA positive allosteric modulator
GC73043 QC-01-175 QC-01-175是一种异双功能分子，可降解异常tau蛋白。
GC16776 QNZ 46 An antagonist of NR2C- and NR2D-subunit containing NMDA receptors
GC73926 QP5038 QP5038（化合物28）是QPCTL的抑制剂，IC50值为3.8nM。
GC49243 Quassin

苦木素,Nigakilactone D
A quassinoid with diverse biological activities
GC14167 Quetiapine

喹硫平; ICI204636
Quetiapine是一种5-HT受体激动剂，对人类5-HT1A受体的 pEC₅₀为4.77。Quetiapine是一种多巴胺受体拮抗剂，对人类D2受体的pIC₅₀为6.33。Quetiapine是一种非典型抗精神病药，用于治疗精神分裂症、躁郁症和重度抑郁症。
GC37055 Quetiapine D4 fumarate

富马酸奎硫平 D4
Quetiapine D4富马酸盐是Quetiapine氘代化合物标准品。
GC39724 Quetiapine D4 hemifumarate

半富马酸奎硫平 D4
Quetiapine D4 hemifumarate 是 Quetiapine hemifumarate 的氘代物。Quetiapine 是一种 5-HT 受体激动剂，也是一种多巴胺受体 (dopamine receptor) 拮抗剂。具有抗抑郁和抗焦虑作用。
GC16891 Quetiapine Fumarate

富马酸喹硫平
An antagonist of diverse neurological receptors
GC48462 Quetiapine-d8 (fumarate)

富马酸喹硫平 d8 (富马酸盐)
An internal standard for the quantification of quetiapine
GC30840 Quinagolide hydrochloride (CV205-502 hydrochloride)

盐酸喹高利特; CV205-502 hydrochloride

Quinagolide hydrochloride (CV205-502 hydrochloride) 是一种选择性多巴胺 D2 受体激动剂，也是一种催乳素抑制剂。