Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

研究方向

Neuroscience 相关产品(3932)

GC33160 amyloid P-IN-1
CAS: 1819986-22-5
纯度: >99.50%
amyloidP-IN-1有利于在疾病或功能失调的治疗中消耗血清淀粉样蛋白P组件(SAP)，包括淀粉样变,阿尔茨海默病，2型糖尿病和关节炎。
GC33341 Transcrocetin (trans-Crocetin)
CAS: 27876-94-4
纯度: >98.00%
A natural apocarotenoid with diverse biological activities
GC33344 WAY 163909
CAS: 428868-32-0
WAY163909是有效的且有选择性的5-HT(2C)receptor激动剂,Ki值为10.5±1.1nM。
GC33434 Methacholine chloride
CAS: 62-51-1
纯度: >98.00%
Methacholine chloride是一种有效的毒蕈碱受体激动剂。Methacholine chloride能够直接作用于平滑肌上的乙酰胆碱受体，导致支气管收缩和气道变窄。
GC33484 Ampyrone (4-Aminoantipyrine)
CAS: 83-07-8
4-Aminoantipyrine(Ampyrone) is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties. It is used as a reagent for biochemical reactions producing peroxides or phenols.
GC33492 Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate)
CAS: 1435786-04-1
纯度: >98.00%
A partial agonist of the NMDA receptor
GC33499 Fexofenadine D6 (MDL-16455 D6)
CAS: 548783-71-7
纯度: >99.00%
Fexofenadine D6 (MDL-16455 D6) 被氘标记为 Fexofenadine，它是一种抗组胺药。
GC33504 4-Acetamidobutanoic acid (N-acetyl GABA)
CAS: 3025-96-5
纯度: >98.00%
A GABA derivative
GC33510 Org-10490
CAS: 83507-02-2
Org-10490是一种dopamineD1受体和dopamineD2受体的拮抗剂，常用于治疗神经疾病。
GC33527 Trimethobenzamide hydrochloride (Ro 2-9578)
CAS: 554-92-7
纯度: >99.50%
A dopamine D 2 receptor antagonist and antiemetic
GC33544 (±)-Methotrimeprazine (D6) (dl-Methotrimeprazine D6)
CAS: 1189805-51-3
纯度: >98.00%
(±)-Levomepromazine D6 ((±)-Methotrimeprazine D6) 是氘标记的 Methotrimeprazine，它是一种 D3 多巴胺和组胺 H1 受体拮抗剂。
GC33552 ABT-670
CAS: 630119-43-6
ABT-670是一种具有选择性，可口服的dopamineD4受体抑制剂。
GC33559 Netupitant metabolite Monohydroxy Netupitant (Monohydroxy Netupitant)
CAS: 910808-12-7
Monohydroxy Netupitant 是 Netupitant 的代谢物，Netupitant 是一种高选择性的 NK1 受体拮抗剂。
GC33573 Rasagiline 13C3 mesylate racemic (AGN1135 13C3 racemic)
CAS: 1216757-55-9
Rasagiline 13C3 mesylate racemic (AGN1135 13C3 racemic) 是一种 13C 标记的 Rasagiline mesylate 外消旋体。
GC33595 β-CGRP, human
CAS: 101462-82-2
β-CGRP, human是一种神经肽激素，由降钙素基因相关肽家族产生，可与降钙素受体样受体CRLR和RAMP形成复合物（CRLR/RAMP1：IC 50 = 1nM；CRLR/RAMP2：IC 50 = 300nM）。
GC33632 Veratric acid (3,4-Dimethoxybenzoic acid)
CAS: 93-07-2
Veratric acid (3,4-Dimethoxybenzoic acid), a simple benzoic acid derived from plants and fruits, has anti-oxidant, anti-inflammation, and blood pressure-lowering effects. Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation.
GC33664 SKF-82958 hydrobromide ((±)-SKF 82958 hydrobromide)
CAS: 74115-01-8
纯度: >99.50%
A dopamine D 1 receptor agonist
GC33668 Naspm (1-Naphthylacetyl spermine)
CAS: 122306-11-0
Naspm (1-Naphthylacetyl semimine) (1-Naphthyl acetyl semimine) 是 Joro 蜘蛛毒素的合成类似物，是一种钙渗透性 AMPA (CP-AMPA) 受体拮抗剂。
GC33673 24-Hydroxycholesterol
CAS: 30271-38-6
纯度: >98.00%
24-Hydroxycholesterol是一种天然的固醇类物质，是n-甲基-d-天门冬氨酸受体(NMDA)和转录因子LXR的激活剂。
GC33674 Methiothepin mesylate (Metitepine mesylate)
CAS: 74611-28-2
纯度: >98.00%
Methiothepin mesylate (Metitepine mesylate) 是一种有效且非选择性的 5-HT2 受体拮抗剂，pKd 值为 7.10 (5-HT1A)、7.28 (5HT1B)、7.56 (5HT1C)、6.99 (5HT1D)、7.0 (5-HT5A) 、7.8 (5-HT5B)、8.74 (5-HT6) 和 8.99 (5-HT7)，以及 8.50 (5HT2A)、8.68 (5HT2B) 和 8.35 (5HT2C) 的 pKis。
GC33677 Iproniazid phosphate
CAS: 305-33-9
纯度: >98.00%
Iproniazid (Marsilid, Iprazid) phosphate is a non-selective, irreversible monoamine oxidase (MAO) inhibitor (MAOI) that is used as an antidepressive agent.
GC33683 Autocamtide 2 (Autocamtide II)
CAS: 129198-88-5
纯度: >98.50%
Autocamtide 2 (Autocamtide II) 是钙/钙调蛋白依赖性蛋白激酶 II (CaMKII) 的高选择性肽底物。
GC33684 Pralidoxime chloride (2-PAM chloride)
CAS: 51-15-0
纯度: >99.00%
An AChE reactivator
GC33685 Tulrampator (CX-1632)
CAS: 1038984-31-4
纯度: >99.00%
Tulrampator (CX-1632) (CX-1632) 是一种口服生物可利用的阳性 AMPAR（AMPA 受体的变构调节剂）。

分类产品列表
货号	产品名称	CAS号	纯度
GC33160	amyloid P-IN-1	1819986-22-5	>99.50%
GC33160	amyloidP-IN-1有利于在疾病或功能失调的治疗中消耗血清淀粉样蛋白P组件(SAP)，包括淀粉样变,阿尔茨海默病，2型糖尿病和关节炎。
GC33341	Transcrocetin (trans-Crocetin)	27876-94-4	>98.00%
GC33341	A natural apocarotenoid with diverse biological activities
GC33344	WAY 163909	428868-32-0	-
GC33344	WAY163909是有效的且有选择性的5-HT(2C)receptor激动剂,Ki值为10.5±1.1nM。
GC33434	Methacholine chloride	62-51-1	>98.00%
GC33434	Methacholine chloride是一种有效的毒蕈碱受体激动剂。Methacholine chloride能够直接作用于平滑肌上的乙酰胆碱受体，导致支气管收缩和气道变窄。
GC33484	Ampyrone (4-Aminoantipyrine)	83-07-8	-
GC33484	4-Aminoantipyrine(Ampyrone) is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties. It is used as a reagent for biochemical reactions producing peroxides or phenols.
GC33492	Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate)	1435786-04-1	>98.00%
GC33492	A partial agonist of the NMDA receptor
GC33499	Fexofenadine D6 (MDL-16455 D6)	548783-71-7	>99.00%
GC33499	Fexofenadine D6 (MDL-16455 D6) 被氘标记为 Fexofenadine，它是一种抗组胺药。
GC33504	4-Acetamidobutanoic acid (N-acetyl GABA)	3025-96-5	>98.00%
GC33504	A GABA derivative
GC33510	Org-10490	83507-02-2	-
GC33510	Org-10490是一种dopamineD1受体和dopamineD2受体的拮抗剂，常用于治疗神经疾病。
GC33527	Trimethobenzamide hydrochloride (Ro 2-9578)	554-92-7	>99.50%
GC33527	A dopamine D 2 receptor antagonist and antiemetic
GC33544	(±)-Methotrimeprazine (D6) (dl-Methotrimeprazine D6)	1189805-51-3	>98.00%
GC33544	(±)-Levomepromazine D6 ((±)-Methotrimeprazine D6) 是氘标记的 Methotrimeprazine，它是一种 D3 多巴胺和组胺 H1 受体拮抗剂。
GC33552	ABT-670	630119-43-6	-
GC33552	ABT-670是一种具有选择性，可口服的dopamineD4受体抑制剂。
GC33559	Netupitant metabolite Monohydroxy Netupitant (Monohydroxy Netupitant)	910808-12-7	-
GC33559	Monohydroxy Netupitant 是 Netupitant 的代谢物，Netupitant 是一种高选择性的 NK1 受体拮抗剂。
GC33573	Rasagiline 13C3 mesylate racemic (AGN1135 13C3 racemic)	1216757-55-9	-
GC33573	Rasagiline 13C3 mesylate racemic (AGN1135 13C3 racemic) 是一种 13C 标记的 Rasagiline mesylate 外消旋体。
GC33595	β-CGRP, human	101462-82-2	-
GC33595	β-CGRP, human是一种神经肽激素，由降钙素基因相关肽家族产生，可与降钙素受体样受体CRLR和RAMP形成复合物（CRLR/RAMP1：IC 50 = 1nM；CRLR/RAMP2：IC 50 = 300nM）。
GC33632	Veratric acid (3,4-Dimethoxybenzoic acid)	93-07-2	-
GC33632	Veratric acid (3,4-Dimethoxybenzoic acid), a simple benzoic acid derived from plants and fruits, has anti-oxidant, anti-inflammation, and blood pressure-lowering effects. Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation.
GC33664	SKF-82958 hydrobromide ((±)-SKF 82958 hydrobromide)	74115-01-8	>99.50%
GC33664	A dopamine D 1 receptor agonist
GC33668	Naspm (1-Naphthylacetyl spermine)	122306-11-0	-
GC33668	Naspm (1-Naphthylacetyl semimine) (1-Naphthyl acetyl semimine) 是 Joro 蜘蛛毒素的合成类似物，是一种钙渗透性 AMPA (CP-AMPA) 受体拮抗剂。
GC33673	24-Hydroxycholesterol	30271-38-6	>98.00%
GC33673	24-Hydroxycholesterol是一种天然的固醇类物质，是n-甲基-d-天门冬氨酸受体(NMDA)和转录因子LXR的激活剂。
GC33674	Methiothepin mesylate (Metitepine mesylate)	74611-28-2	>98.00%
GC33674	Methiothepin mesylate (Metitepine mesylate) 是一种有效且非选择性的 5-HT2 受体拮抗剂，pKd 值为 7.10 (5-HT1A)、7.28 (5HT1B)、7.56 (5HT1C)、6.99 (5HT1D)、7.0 (5-HT5A) 、7.8 (5-HT5B)、8.74 (5-HT6) 和 8.99 (5-HT7)，以及 8.50 (5HT2A)、8.68 (5HT2B) 和 8.35 (5HT2C) 的 pKis。
GC33677	Iproniazid phosphate	305-33-9	>98.00%
GC33677	Iproniazid (Marsilid, Iprazid) phosphate is a non-selective, irreversible monoamine oxidase (MAO) inhibitor (MAOI) that is used as an antidepressive agent.
GC33683	Autocamtide 2 (Autocamtide II)	129198-88-5	>98.50%
GC33683	Autocamtide 2 (Autocamtide II) 是钙/钙调蛋白依赖性蛋白激酶 II (CaMKII) 的高选择性肽底物。
GC33684	Pralidoxime chloride (2-PAM chloride)	51-15-0	>99.00%
GC33684	An AChE reactivator
GC33685	Tulrampator (CX-1632)	1038984-31-4	>99.00%
GC33685	Tulrampator (CX-1632) (CX-1632) 是一种口服生物可利用的阳性 AMPAR（AMPA 受体的变构调节剂）。