Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC17192 Quinelorane hydrochloride

LY163502
Quinelorane hydrochloride (LY163502) 是一种有效的多巴胺 D3/D2 受体激动剂。
GC14547 Quinolinic acid

喹啉酸
An excitotoxic agonist at NMDA receptors
GC31820 Quinotolast sodium (FR71021)

FR71021
浓度范围为 1-100 μg/mL 的 Quinotolast sodium (FR71021) 以浓度依赖性方式抑制组胺、LTC4 和 PGD2 的释放。
GC14583 R 59-022

DKGI-I; Diacylglycerol kinase inhibitor I
R 59-022是一种二酰甘油激酶抑制剂（IC₅₀ = 2.8µM）。
GC18397 R-(-)-α-Methylhistamine (hydrochloride)

(R)-(-)-α-甲基组胺二盐酸盐
A histamine H₃ receptor agonist
GP10032 Rac GTPase fragment

H2N-Val-Phe-Asp-Glu-Ala-Ile-Arg-Ala-Val-OH

Fragment of small signaling G proteins
GC49157 rac-5-carboxy Tolterodine

5-羧基托特罗定
An inactive metabolite of tolterodine
GC48999 rac-Aprepitant-d4 An internal standard for the quantification of aprepitant
GC49203 rac-Desethyl Oxybutynin (hydrochloride)

(R,S)-DEOB
An active metabolite of oxybutynin
GC49904 rac-Eletriptan-d3 (hydrobromide) An internal standard for the quantification of eletriptan
GC37067 rac-Rotigotine Hydrochloride

5,6,7,8-四氢-6-[丙基[2-(2-噻吩基)乙基]氨基]-1-萘酚盐酸盐
rac-Rotigotine Hydrochloride 是D-2受体选择性激动剂，Ki为0.69 nM。
GC48461 rac-trans-4-hydroxy Glyburide

4-trans-hydroxycyclohexyl Glyburide, 4-trans-hydroxy Glibenclamide
An active metabolite of glyburide
GC38111 Rac-VU 6008667 Rac-VU 6008667 是毒蕈碱乙酰胆碱受体亚型 5 (M5 NAM) 的选择性负变构调节剂，对于人和大鼠的 IC50 值分别为 1.2 μM 和 1.6 μM。Rac-VU 6008667 具有高 CNS 渗透性。
GC37064 Racanisodamine

消旋山莨菪碱
A natural α₁-adrenoceptor antagonist
GC49108 Racecadotril-d5

消旋卡多曲杂质,Acetorphan-d5
An internal standard for the quantification of racecadotril
GC16769 Raclopride

雷氯必利
Raclopride是一种取代的苯甲酰胺，是具有高选择性的多巴胺D₂和D₃受体拮抗剂。
GC65513 Radequinil

AC-3933
Radequinil (AC-3933) 是一种苯二氮卓类受体 (BzR) 部分反向激动剂。AC-3933 与 GABA(-) 和 GABA(+) 配体结合，Ki 分别为 5.15 和 6.11 nM。
GC34753 Radiprodil

RGH-896

An NMDA receptor antagonist
GC50401 RAGE antagonist peptide

拮抗剂多肽RAGEANTAGONIST
RAGE 拮抗剂肽是一种晚期糖基化终产物 (RAGE) 拮抗剂。
GC62702 RAGE antagonist peptide TFA RAGE antagonist peptide TFA 是一种晚期糖基化终产物 (RAGE) 拮抗剂。RAGE antagonist peptide TFA 可阻断 RAGE 和几个重要配体 HMGB-1，S100P，S100A4 的结合。RAGE antagonist peptide TFA 具有抗肿瘤和抗炎活性。
GC40237 Ramelteon-d5

TAK-375-d5
An internal standard for the quantification of ramelteon
GC15639 Ramosetron Hydrochloride

盐酸雷莫司琼; YM060
A potent, selective 5-HT₃ receptor antagonist
GC12365 Ranitidine hydrochloride

盐酸雷尼替丁
A histamine H₂ receptor antagonist
GC30971 Rapacuronium bromide (Org 9487)

Org 9487
雷帕库溴铵 (Org 9487) (Org 9487) 是一种非去极化神经肌肉阻滞剂，是毒蕈碱乙酰胆碱受体 (mAChR) 的变构调节剂。
GC33492 Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate)

GLYX-13 Trifluoroacetate
A partial agonist of the NMDA receptor
GC33714 Rasagiline (AGN1135)

雷沙吉兰; (R)-AGN1135; TVP1012
An inhibitor of MAO-B
GC33573 Rasagiline 13C3 mesylate racemic (AGN1135 13C3 racemic)

AGN1135 13C3; TVP1012 13C3 racemic
Rasagiline 13C3 mesylate racemic (AGN1135 13C3 racemic) 是一种 13C 标记的 Rasagiline mesylate 外消旋体。
GC12801 Rasagiline Mesylate

甲磺酸雷沙吉兰; (R)-AGN1135 mesylate; TVP1012 mesylate
An inhibitor of MAO-B
GC48028 Rasagiline-13C3 (mesylate)

甲磺酸雷沙吉兰-13C3
An internal standard for the quantification of rasagiline
GC44807 RBI 257 (maleate) A selective dopamine D₄ receptor antagonist
GC48029 RC363 An inhibitor of ferroptosis
GC48030 RC574
An inhibitor of ferroptosis
GC17367 Rebamipide

瑞巴派特; OPC12759; Proamipide
A gastroprotective agent and mucin secretagogue
GC61234 Rebamipide D4

瑞巴派特 D4; OPC12759-d4; Proamipide-d4
An internal standard for the quantification of rebamipide
GC63398 Rebamipide mofetil Rebamipide mofetil is an orally active prodrug of Rebamipide (OPC12759). Rebamipide induces COX-2 expression, increases PGE2 levels, and enhances gastric mucosal defense in a COX-2-dependent manner.
GC44810 Reduced Haloperidol

还原氟哌啶醇
An active metobolite of haloperidol
GC61235 Regaloside B

王百合苷 B
RegalosideB是一种从Liliumlongiflorum中分离出来的苯丙烷。RegalosideB可以抑制iNOS和COX-2的表达，具有抗炎活性。
GC61238 Rehmapicrogenin

地黄苦苷元

Rehmapicrogenin可从Rehmanniaglutinosa的根部分离得到，通过抑制iNOS、COX-2和IL-6表现出有效的抗炎作用。
GC71618 rel-Sertraline-d3 hydrochloride rel-Sertraline-d3 hydrochloride是氘标记的盐酸舍曲林。
GC63169 Relenopride hydrochloride

YKP10811 hydrochloride
Relenopride (YKP10811) hydrochloride 是一种特异性和选择性的 5-HT4 受体激动剂 (Ki=4.96 nM)。与5-HT4相比，Relenopride hydrochloride 对 5-HT2A (Ki=600 nM)和5-HT2B (Ki=31 nM) 受体的亲和力分别低 120 倍和 6 倍。Relenopride hydrochloride 增加胃肠运动。
GC73886 Remacemide

FPL 12924; PR 934-423; FPL 13592
Remacemide（FPL 12924）是一种口服活性、非竞争性、低亲和力NMDA受体拮抗剂。
GC14822 Remoxipride hydrochloride

瑞莫必利盐酸盐
An atypical antipsychotic
GC31812 ReN-1869 hydrochloride (NNC-05-1869 hydrochloride)

NNC-05-1869 hydrochloride
ReN 1869 hydrochloride 是一种新型选择性组胺 H1 受体拮抗剂，对组胺 H1 受体（豚鼠脑）具有亲和力，Ki 为 0.19±；0.04 μ；M 和非选择性 σ；位点（豚鼠脑），Ki 为 0.45 μ；M.
GC67923 Renzapride

BRL 24924
Renzapride (BRL 24924)，是一种取代苯甲酰胺，是 5-HT4 受体激动剂，也是 5HT2b 和 5HT3 受体拮抗剂。Renzapride (BRL 24924) 可以用于便秘型肠易激综合征 (C-IBS) 的研究。
GC64423 Repinotan hydrochloride

BAY x 3702
Repinotan hydrochloride (BAY x 3702) 是一种有效的、选择性的、可透过血脑屏障，并具有口服活性的 5-HT1A 受体激动剂，Ki 值为 0.19 nM (小牛海马)， 0.25 nM (大鼠和人类皮层) 和 0.59 nM (大鼠海马)。Repinotan hydrochloride 对其他相关受体的亲和力较弱。Repinotan hydrochloride 具有强效的神经保护作用。
GC70309 Repirinast Repirinast（MY-5116）是一种口服活性抗过敏剂。
GC48040 Reserpiline

利舍匹林
An indole alkaloid
GC48041 Resolvin D1-d5

RvD1-d5
An internal standard for the quantification of RvD1
GC40982 Resolvin D5

7(S),17(S)-diHDHA
A potent anti-inflammatory, pro-resolving lipid mediator
GC12599 Retigabine dihydrochloride

瑞替加滨,D 20443 dihydrochloride;D-20443 dihydrochloride;D20443 dihydrochloride
An Analytical Reference Standard