Neuroscience
Neuroscience(神经科学)
Neuroscience
Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more
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Neuroscience 相关产品(3932)
- GC31393Pumosetrag Hydrochloride (MKC-733)CAS: 194093-42-0纯度: >99.50%
Pumoserag Hydrochloride (MKC-733) (MKC-733; DDP-733) 是一种口服 5-HT3 部分激动剂，用于治疗肠易激综合征和胃食管反流病。
- GC31407Sograzepide (Netazepide)CAS: 155488-25-8纯度: >98.00%
Sograzepide (Netazepide)是一种口服活性高、选择性强且效力强的胃泌素/CCK-B拮抗剂，IC 50 值为 0.1nM，对胃泌素/CCK-A活性具有抑制作用，IC 50 为502nM。
- GC31418Clebopride malateCAS: 57645-91-7纯度: >99.50%
Clebopride is a dopamine antagonist drug and is used to treat functional gastrointestinal disorder such as nausea or vomiting.
- GC31422MCH-1 antagonist 1CAS: 1039825-68-7
MCH-1antagonist1是一种有效的黑色素浓缩激素1(MCH-1)拮抗剂，Ki值为2.6nM。MCH-1antagonist1还抑制CYP3A4，IC50为10μM。
- GC31479BMS-819881CAS: 1197420-05-5
BMS-819881是一种黑色素浓缩激素受体1(MCHR1)拮抗剂，结合大鼠MCHR1，Ki值为7nM。BMS-819881还有效且选择性地作用于CYP3A4，EC50为13μM.
- GC31505MCHr1 antagonist 2CAS: 863115-70-2纯度: >98.00%
MCHr1antagonist2是一种黑色素聚集激素受体1(melaninconcentratinghormonereceptor1)拮抗剂，IC50值为65nM；MCHr1antagonist2同时抑制hERG，在IMR-32细胞中，IC50值为4.0nM。
- GC31558CCK-A receptor inhibitor 1CAS: 137004-80-9
CCK-Areceptorinhibitor1是一种缩胆囊素A(cholecystokininA,CCK-A)受体抑制剂，IC50为340nM。
- GC31628MCHr1 antagonist 1CAS: 391610-37-0
MCHr1antagonist1是一种选择性的黑色素浓集激素1型受体(melaninconcentratinghormone-1receptor)拮抗剂，对人MCH1受体的Kb和Ki值分别为1nM和4nM，在降低体重方面可能起作用。
- GC31690Batefenterol (GSK961081)CAS: 743461-65-6纯度: >99.00%
A muscarinic receptor antagonist and β 2 -adrenergic receptor agonist
- GC31693AdelmidrolCAS: 1675-66-7纯度: >98.00%
Adelmidrol is an analogue of palmitoylethanolamide (PEA) with anti-inflammatory activities.
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC31393 | Pumosetrag Hydrochloride (MKC-733) | 194093-42-0 | >99.50% | |
Pumoserag Hydrochloride (MKC-733) (MKC-733; DDP-733) 是一种口服 5-HT3 部分激动剂，用于治疗肠易激综合征和胃食管反流病。 | ||||
| GC31407 | Sograzepide (Netazepide) | 155488-25-8 | >98.00% | |
Sograzepide (Netazepide)是一种口服活性高、选择性强且效力强的胃泌素/CCK-B拮抗剂，IC 50 值为 0.1nM，对胃泌素/CCK-A活性具有抑制作用，IC 50 为502nM。 | ||||
| GC31418 | Clebopride malate | 57645-91-7 | >99.50% | |
Clebopride is a dopamine antagonist drug and is used to treat functional gastrointestinal disorder such as nausea or vomiting. | ||||
| GC31422 | MCH-1 antagonist 1 | 1039825-68-7 | - | |
MCH-1antagonist1是一种有效的黑色素浓缩激素1(MCH-1)拮抗剂，Ki值为2.6nM。MCH-1antagonist1还抑制CYP3A4，IC50为10μM。 | ||||
| GC31440 | Syringaldehyde | 134-96-3 | >98.00% | |
A polyphenol with diverse biological activities | ||||
| GC31455 | Niperotidine | 84845-75-0 | - | |
Niperotidine是一种组胺H2受体(histamineH2-receptor)拮抗剂。 | ||||
| GC31477 | Tarazepide | 141374-81-4 | - | |
Tarazepide是一种有效且特异性的CCK-A受体拮抗剂。 | ||||
| GC31479 | BMS-819881 | 1197420-05-5 | - | |
BMS-819881是一种黑色素浓缩激素受体1(MCHR1)拮抗剂，结合大鼠MCHR1，Ki值为7nM。BMS-819881还有效且选择性地作用于CYP3A4，EC50为13μM. | ||||
| GC31503 | YM348 | 372163-84-3 | - | |
YM348是一种口服有效的5-HT2C受体激动剂，对克隆的人类5-HT2C受体具有高亲和力，Ki为0.89nM。 | ||||
| GC31504 | NGD-4715 | 476322-70-0 | - | |
NGD-4715是选择性，有口服活性的黑色素浓缩激素受体1(melanin-concentratinghormonereceptor1(MCHR1))的拮抗剂。 | ||||
| GC31505 | MCHr1 antagonist 2 | 863115-70-2 | >98.00% | |
MCHr1antagonist2是一种黑色素聚集激素受体1(melaninconcentratinghormonereceptor1)拮抗剂，IC50值为65nM；MCHr1antagonist2同时抑制hERG，在IMR-32细胞中，IC50值为4.0nM。 | ||||
| GC31506 | SB-568849 | 395679-53-5 | - | |
SB-568849是一种黑色素浓缩激素受体1(MCHR1)拮抗剂，pKi值为7.7。 | ||||
| GC31538 | AT-1002 | 835872-35-0 | - | |
AT-1002是一种6聚体合成肽，是一种紧密连接的调节剂和吸收增强剂。 | ||||
| GC31558 | CCK-A receptor inhibitor 1 | 137004-80-9 | - | |
CCK-Areceptorinhibitor1是一种缩胆囊素A(cholecystokininA,CCK-A)受体抑制剂，IC50为340nM。 | ||||
| GC31592 | GI 181771 | 305366-98-7 | - | |
GI181771是研究用于治疗肥胖症的胆囊收缩素1(cholecystokinin1)受体激动剂。 | ||||
| GC31613 | SR 146131 | 221671-61-0 | >98.00% | |
SR146131是一种有效，有口服活性，选择性的非多肽缩胆囊素1(cholecystokinin1)受体激动剂。 | ||||
| GC31628 | MCHr1 antagonist 1 | 391610-37-0 | - | |
MCHr1antagonist1是一种选择性的黑色素浓集激素1型受体(melaninconcentratinghormone-1receptor)拮抗剂，对人MCH1受体的Kb和Ki值分别为1nM和4nM，在降低体重方面可能起作用。 | ||||
| GC31643 | AZD1979 | 1254035-84-1 | - | |
AZD1979是一个Melanin-concentratinghormonereceptor1(MCHr1)拮抗剂,其IC50值约为12nM。 | ||||
| GC31690 | Batefenterol (GSK961081) | 743461-65-6 | >99.00% | |
A muscarinic receptor antagonist and β 2 -adrenergic receptor agonist | ||||
| GC31693 | Adelmidrol | 1675-66-7 | >98.00% | |
Adelmidrol is an analogue of palmitoylethanolamide (PEA) with anti-inflammatory activities. | ||||
| GC31695 | Acrivastine (BW825C) | 87848-99-5 | >98.00% | |
A histamine H 1 receptor antagonist | ||||
| GC31699 | Scopoletin (Gelseminic acid) | 92-61-5 | >98.00% | |
A natural coumarin | ||||
| GC31706 | Ginsenoside Rg5 | 186763-78-0 | >98.00% | |
A ginsenoside with diverse biological activities | ||||
| GC31707 | Chebulagic acid | 23094-71-5 | >98.00% | |
A polyphenol with diverse biological activities | ||||