Neuroscience(神经科学)

Neuroscience
Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more
Products for Neuroscience
- 5-HT Receptor(420)
- AChR(53)
- AChE(100)
- Alzheimer(107)
- Amyloid β(118)
- BACE(4)
- CGRP (33)
- COX(294)
- DAPK(7)
- Dopamine Receptor(290)
- GABA Receptor(155)
- Gap Junction(16)
- GluR(116)
- Histamine(2)
- Histamine Receptor(236)
- mPEGS-1(4)
- Muscarinic Receptor(41)
- Neuroscience Peptides(38)
- Nicotinic Receptor(62)
- P2 Receptor(2)
- P2X7 receptor(3)
- SSRIs(5)
- Substance P/NK1 Receptor(20)
- NMDA(2)
- Beta-secretase(25)
- CaMK(32)
- Dopamine Transporter(20)
- Monoamine Oxidase(91)
- Serotonin Transporter(57)
- nAChR(100)
- iGluR(155)
- Neurokinin Receptor(75)
- MCHR1 (GPR24)(16)
- mAChR(183)
- GPR139(4)
- Cholecystokinin Receptor(25)
- Behavioral Neuroscience(353)
- DREADD(1)
- Huntington(14)
- Neuroendocrinology(64)
- Neuroprotection(117)
- Ophthalmology(158)
- Pain Research(229)
- Parkinson(73)
- Prion(7)
- Seizure Disorders(94)
- Cholinesterases(13)
- Tau Protein(4)
- Neurodegenerative Disorders(5)
- Cholinesterase (ChE)(3)
- Amyloid-β(9)
- γ-secretase(1)
- Ischemia(3)
- Cat.No. 产品名称 Information
-
GC11810
PG 01037 dihydrochloride
A selective dopamine D3 receptor antagonist
-
GC15146
PHA 543613 hydrochloride
PHA 543613 hydrochloride 是一种有效的、口服活性的、脑渗透性和选择性的 α7 nAChR 激动剂,Ki 为 8.8 nM。
-
GC12678
PHA 568487
PHA 568487 是一种选择性 α7 烟碱型乙酰胆碱受体 (α-7 nAchR) 激动剂。
-
GC17383
PHCCC
N-苯基-7-(羟基亚胺基)环丙烯并[B]苯并吡喃-1A-甲酰胺
PHCCC 是 I 组 mGluR 拮抗剂,IC50 为 3 μM。 PHCCC 是 mGlu4 受体的选择性正调节剂。抗帕金森效应。 -
GC15928
Phenacetin
非那西丁; Acetophenetidin
An Analytical Reference Standard -
GC66429
Phenacetin-d5
Acetophenetidin-d5
Phenacetin-d5 (Acetophenetidin-d5) 是 Phenacetin 的氘代物。Phenacetin (Acetophenetidin) 是一种非阿片类解热化合物,可用于缓解疼痛的研究。Phenacetin 是一种选择性的 COX-3 抑制剂。Phenacetin 能作为人肝微粒体和大鼠体内 CYP1A2 的探针。 -
GC30773
Phenelzine sulfate
硫酸苯乙肼
Phenelzine是一种单胺氧化酶(MAO)抑制剂。 -
GC46200
Phenelzine-d5 (sulfate)
硫酸苯乙肼 d5 (硫酸盐)
An internal standard for the quantification of phenelzine -
GC63146
Phenibut
菲尼布特,β-Phenyl-GABA; 4-Amino-3-phenylbutanoic acid
An Analytical Reference Standard
-
GC61180
Phenidone
菲尼酮
Phenidone (1-phenyl-3-pyrazolidinone), a dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), is an organic compound that is primarily used as a photographic developer. -
GC69697
Pheniprazine hydrochloride
β-Phenylisopropylhydrazine hydrochloride
Pheniprazine hydrochloride 是一种有效的长效 monoamine oxidase 抑制剂。Pheniprazine hydrochloride 具有研究抑郁症的潜力。 -
GC16787
Pheniramine Maleate
马来酸非尼拉敏; Prophenpyridamine maleate; Tripoton maleate
Histamine receptor antagonist -
GC47946
Phenol-13C6
苯酚-13C6
A building block -
GC46202
Phenoxybenzamine-d5 (hydrochloride)
盐酸酚苄明 d5 (盐酸盐)
An internal standard for the quantification of phenoxybenzamine -
GC13783
Phenserine
苯丝氨酸,(-)-Eseroline phenylcarbamate; (-)-Phenserine
An AChE inhibitor -
GC45999
Phentolamine-d4 (hydrochloride)
An internal standard for the quantification of phentolamine
-
GC19921
Phenylarsine Oxide
氧化苯胂,Arsenoso-Benzen;FenylArsinoxid;Oxophenyl-Arsin;Oxophenylarsine;Pao;Phenyl Arsene Oxide;Phenyl ARSENOxide;PhenylARSINE Oxide
An organoarsenic compound -
GC30953
Phenylbiguanide (N-Phenylbiguanide)
1-苯基双胍,N-Phenylbiguanide; PBG; 1-Phenylbiguanide
1-Phenylbiguanide (Phenylbiguanide, PBG, N-Phenylbiguanide) is a 5-hydroxytryptamine3 (5-HT3) receptor agonist with EC50 of 3.0 μM. -
GC15008
Phenylbutazone
保泰松
An NSAID and COX inhibitor -
GC65108
Phenylbutazone(diphenyl-d10)
保泰松 d10
An NSAID and COX inhibitor -
GC69699
Phenylbutazone-13C12
Phenylbutazone-13C12 是 13C12 标记的 Phenylbutazone。Phenylbutazone 是有效的前列腺素 H 合酶 (PHS) 过氧化物酶的还原辅助因子。Phenylbutazone 是一种肝毒素,是非甾体类抗炎剂 (NSAID)。Phenylbutazone 诱导肌肉盲样蛋白1 (MBNL1) 表达,有用于强直性脊柱炎研究的潜力。
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GC49128
Phenylbutazone-d9
保泰松 d9
An internal standard for the quantification of phenylbutazone -
GC48861
Phenytoin-d10
苯妥英D10,5,5-Diphenylhydantoin-d10
An internal standard for the quantification of phenytoin -
GC74385
PHF6 TFA
PHF6 TFA是一种能够引发全长tau蛋白聚集的自组装序列。
-
GC12703
Philanthotoxin 74
PhTx 74 dihydrochloride
An AMPA receptor antagonist -
GC47955
Phloroglucinol
间苯三酚
A phenol with diverse biological activities -
GC44631
Phosphatidylethanolamines (bovine)
磷酯酰乙醇胺
Phosphatidylethanolamines (bovine)是真核细胞中第二丰富的甘油磷脂,占哺乳动物细胞总磷脂的15% - 25%。 -
GC44632
Phosphatidylethanolamines (egg)
磷脂酰乙醇胺
A glycerophospholipid -
GC18560
Phosphatidylethanolamines (soy)
磷脂酰乙醇胺(大豆)
A mixture of phosphatidylethanolamines isolated from soy -
GC31156
Physalaemin
Physalaemin是一种非哺乳动物类的速激肽,选择性地高亲和力结合到神经激肽-1(NK1)受体。
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GC17391
Physostigmine hemisulfate
毒扁豆碱半硫酸盐; Eserine hemisulfate
毒扁豆碱半硫酸盐 (Eserine hemisulfate) 是一种可逆的乙酰胆碱酯酶 (AChE) 抑制剂。
-
GC19294
Piboserod
哌波色罗,SB-207266
A selective, potent 5-HT4 receptor antagonist -
GC36912
Piboserod hydrochloride
SB-207266 hydrochloride
Piboserod (SB 207266)盐酸盐是5-羟色胺受体5-HT4选择性抑制剂。 -
GC46206
Picamilon
匹卡米隆,Nicotinoyl-GABA; Nicotinoyl-γ-aminobutyric acid
A GABA derivative -
GC38411
Picfeltarraenin IA
苦玄参苷 IA
Picfeltarraenin IA is an AChE inhibitior, and an potential PI3K and EGFR inhibitor. It also acts as an inhibitor on both the classical and alternative pathways of the complement system. -
GC36915
Picfeltarraenin IB
苦玄参苷 IB
Picfeltarraenin IB, a cucurbitacin glycoside isolated from Picriafel-terrae, is an inhibitor of acetylcholinesterase (AChE). Picfeltarraenin IB can be used for the treatment of herpes infections, cancer and inflammation. -
GC36916
Picfeltarraenin IV
苦玄参苷 IV
Picfeltarraenin IV 是一种三萜类化合物,可从 Picriafel-terrae Lour (P.fel-terrae) 中提取。Picfeltarraenin IV 是一种乙酰胆碱酯酶 (AChE) 抑制剂。Picfeltarraenin IV 可用于治疗感染,癌症和炎症。 -
GC18511
Picrotoxin
苦毒浆果[木防已属],Cocculin;Picrotoxin;Picrotin
Picrotoxin(Cocculin)是一种植物生物碱,是 GABAA受体的非竞争性拮抗剂,可阻断GABAA受体的氯离子通道。 -
GC61186
Picrotoxinin
木防己苦毒宁
Picrotoxinin, a potent convulsant, is a chloride channel blocker. Picrotoxinin is a noncompetitive GABAA receptor antagonist, which negatively modulates the action of GABA on GABAAA receptors. -
GC17256
Pilocarpine HCl
盐酸毛果芸香碱
A muscarinic acetylcholine receptor agonist
-
GC31001
Pilocarpine nitrate
硝酸毛果芸香碱
Pilocarpinenitrate是一种选择性的M3型毒蕈碱乙酰胆碱受体(M3muscarinicreceptor)激动剂。 -
GC11844
Pimavanserin
匹莫范色林; ACP-103
A 5-HT2A inverse agonist -
GC36919
Pimavanserin tartrate
匹莫范色林L-酒石酸盐,ACP-103 hemitartrate
A 5-HT2A inverse agonist -
GC30999
Pimethixene (Pimetixene)
匹美噻吨,Pimetixene
Pimethixene (Pimetixene) 是抗组胺药和抗血清素能化合物,用作抗偏头痛剂。 -
GC65296
Pimethixene maleate
匹美噻吨马来酸盐; Pimetixene maleate
Pimethixene (Pimetixene) maleate, an antihistamine, anntimigraine agent and antiserotonergic compound, is a highly potent antagonist of a broad range of monoamine receptors, including a variety of serotonin receptors. Pimethixene maleate inhibits 5-HT2A, 5-HT2B, 5-HT2C, 5-HT1A, 5-HT1B, 5-HT6, 5-HT7, Adrenergic α-1A, Dopamine D1 Receptor, Dopamine D2 Receptor, Dopamine D4.4 Receptor, Histamine H1 Receptor, Muscarinic M1 and Muscarinic M2 with pKi of 10.22, 10.44, 8.42, 7.63, < 5, 7.30, 7.28, 7.61, 6.37, 8.19, 7.54, 10.14, 8.61 and 9.38, respectively. -
GC10643
Pimozide
匹莫齐特; R6238
Pimozide是一种化学结构新颖、高效且口服长效的神经阻滞剂类多巴胺受体抑制剂,对多巴胺D2、D3和D4 受体的Ki值分别为2.4nM、0.2nM和1.8nM。 -
GC45756
Pimozide-d4
R6238-d4
An internal standard for the quantification of pimozide -
GC67752
Pimozide-d4-1
R6238-d4-1
Pimozide-d4-1 氘代标记的 Pimozide。Pimozide 是 dopamine receptor 的拮抗剂,对 dopamine D2,D3 和 D1 受体的 Ki 值分别为 1.4 nM,2.5 nM 和 588 nM,同时对 α1-adrenoceptor 也有较高亲和性,Ki 值为 39 nM;Pimozide 也是 STAT3 和 STAT5 的抑制剂。 -
GC18707
Pimprinine
5-(1H-吲哚基)2-甲基噁唑
An alkaloid with diverse biological activities -
GC17734
Pindolol
吲哚洛尔; LB-46
A β1- and β2-AR antagonist