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Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. 产品名称 Information
  2. GC11810 PG 01037 dihydrochloride A selective dopamine D3 receptor antagonist
  3. GC15146 PHA 543613 hydrochloride PHA 543613 hydrochloride 是一种有效的、口服活性的、脑渗透性和选择性的 α7 nAChR 激动剂,Ki 为 8.8 nM。
  4. GC12678 PHA 568487 PHA 568487 是一种选择性 α7 烟碱型乙酰胆碱受体 (α-7 nAchR) 激动剂。
  5. GC17383 PHCCC

    N-苯基-7-(羟基亚胺基)环丙烯并[B]苯并吡喃-1A-甲酰胺

    PHCCC 是 I 组 mGluR 拮抗剂,IC50 为 3 μM。 PHCCC 是 mGlu4 受体的选择性正调节剂。抗帕金森效应。
  6. GC15928 Phenacetin

    非那西丁; Acetophenetidin

    An Analytical Reference Standard
  7. GC66429 Phenacetin-d5

    Acetophenetidin-d5

    Phenacetin-d5 (Acetophenetidin-d5) 是 Phenacetin 的氘代物。Phenacetin (Acetophenetidin) 是一种非阿片类解热化合物,可用于缓解疼痛的研究。Phenacetin 是一种选择性的 COX-3 抑制剂。Phenacetin 能作为人肝微粒体和大鼠体内 CYP1A2 的探针。
  8. GC30773 Phenelzine sulfate

    硫酸苯乙肼

    Phenelzine是一种单胺氧化酶(MAO)抑制剂。
  9. GC46200 Phenelzine-d5 (sulfate)

    硫酸苯乙肼 d5 (硫酸盐)

    An internal standard for the quantification of phenelzine
  10. GC63146 Phenibut

    菲尼布特,β-Phenyl-GABA; 4-Amino-3-phenylbutanoic acid

    An Analytical Reference Standard

  11. GC61180 Phenidone

    菲尼酮

    Phenidone (1-phenyl-3-pyrazolidinone), a dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), is an organic compound that is primarily used as a photographic developer.
  12. GC69697 Pheniprazine hydrochloride

    β-Phenylisopropylhydrazine hydrochloride

    Pheniprazine hydrochloride 是一种有效的长效 monoamine oxidase 抑制剂。Pheniprazine hydrochloride 具有研究抑郁症的潜力。
  13. GC16787 Pheniramine Maleate

    马来酸非尼拉敏; Prophenpyridamine maleate; Tripoton maleate

    Histamine receptor antagonist
  14. GC47946 Phenol-13C6

    苯酚-13C6

    A building block
  15. GC46202 Phenoxybenzamine-d5 (hydrochloride)

    盐酸酚苄明 d5 (盐酸盐)

    An internal standard for the quantification of phenoxybenzamine
  16. GC13783 Phenserine

    苯丝氨酸,(-)-Eseroline phenylcarbamate; (-)-Phenserine

    An AChE inhibitor
  17. GC45999 Phentolamine-d4 (hydrochloride) An internal standard for the quantification of phentolamine
  18. GC19921 Phenylarsine Oxide

    氧化苯胂,Arsenoso-Benzen;FenylArsinoxid;Oxophenyl-Arsin;Oxophenylarsine;Pao;Phenyl Arsene Oxide;Phenyl ARSENOxide;PhenylARSINE Oxide

    An organoarsenic compound
  19. GC30953 Phenylbiguanide (N-Phenylbiguanide)

    1-苯基双胍,N-Phenylbiguanide; PBG; 1-Phenylbiguanide

    1-Phenylbiguanide (Phenylbiguanide, PBG, N-Phenylbiguanide) is a 5-hydroxytryptamine3 (5-HT3) receptor agonist with EC50 of 3.0 μM.
  20. GC15008 Phenylbutazone

    保泰松

    An NSAID and COX inhibitor
  21. GC65108 Phenylbutazone(diphenyl-d10)

    保泰松 d10

    An NSAID and COX inhibitor
  22. GC69699 Phenylbutazone-13C12 Phenylbutazone-13C12 是 13C12 标记的 Phenylbutazone。Phenylbutazone 是有效的前列腺素 H 合酶 (PHS) 过氧化物酶的还原辅助因子。Phenylbutazone 是一种肝毒素,是非甾体类抗炎剂 (NSAID)。Phenylbutazone 诱导肌肉盲样蛋白1 (MBNL1) 表达,有用于强直性脊柱炎研究的潜力。
  23. GC49128 Phenylbutazone-d9

    保泰松 d9

    An internal standard for the quantification of phenylbutazone
  24. GC48861 Phenytoin-d10

    苯妥英D10,5,5-Diphenylhydantoin-d10

    An internal standard for the quantification of phenytoin
  25. GC74385 PHF6 TFA PHF6 TFA是一种能够引发全长tau蛋白聚集的自组装序列。
  26. GC12703 Philanthotoxin 74

    PhTx 74 dihydrochloride

    An AMPA receptor antagonist
  27. GC47955 Phloroglucinol

    间苯三酚

    A phenol with diverse biological activities
  28. GC44631 Phosphatidylethanolamines (bovine)

    磷酯酰乙醇胺

    Phosphatidylethanolamines (bovine)是真核细胞中第二丰富的甘油磷脂,占哺乳动物细胞总磷脂的15% - 25%。
  29. GC44632 Phosphatidylethanolamines (egg)

    磷脂酰乙醇胺

    A glycerophospholipid
  30. GC18560 Phosphatidylethanolamines (soy)

    磷脂酰乙醇胺(大豆)

    A mixture of phosphatidylethanolamines isolated from soy
  31. GC31156 Physalaemin

    Physalaemin是一种非哺乳动物类的速激肽,选择性地高亲和力结合到神经激肽-1(NK1)受体。

  32. GC17391 Physostigmine hemisulfate

    毒扁豆碱半硫酸盐; Eserine hemisulfate

    毒扁豆碱半硫酸盐 (Eserine hemisulfate) 是一种可逆的乙酰胆碱酯酶 (AChE) 抑制剂。

  33. GC19294 Piboserod

    哌波色罗,SB-207266

    A selective, potent 5-HT4 receptor antagonist
  34. GC36912 Piboserod hydrochloride

    SB-207266 hydrochloride

    Piboserod (SB 207266)盐酸盐是5-羟色胺受体5-HT4选择性抑制剂。
  35. GC46206 Picamilon

    匹卡米隆,Nicotinoyl-GABA; Nicotinoyl-γ-aminobutyric acid

    A GABA derivative
  36. GC38411 Picfeltarraenin IA

    苦玄参苷 IA

    Picfeltarraenin IA is an AChE inhibitior, and an potential PI3K and EGFR inhibitor. It also acts as an inhibitor on both the classical and alternative pathways of the complement system.
  37. GC36915 Picfeltarraenin IB

    苦玄参苷 IB

    Picfeltarraenin IB, a cucurbitacin glycoside isolated from Picriafel-terrae, is an inhibitor of acetylcholinesterase (AChE). Picfeltarraenin IB can be used for the treatment of herpes infections, cancer and inflammation.
  38. GC36916 Picfeltarraenin IV

    苦玄参苷 IV

    Picfeltarraenin IV 是一种三萜类化合物,可从 Picriafel-terrae Lour (P.fel-terrae) 中提取。Picfeltarraenin IV 是一种乙酰胆碱酯酶 (AChE) 抑制剂。Picfeltarraenin IV 可用于治疗感染,癌症和炎症。
  39. GC18511 Picrotoxin

    苦毒浆果[木防已属],Cocculin;Picrotoxin;Picrotin

    Picrotoxin(Cocculin)是一种植物生物碱,是 GABAA受体的非竞争性拮抗剂,可阻断GABAA受体的氯离子通道。
  40. GC61186 Picrotoxinin

    木防己苦毒宁

    Picrotoxinin, a potent convulsant, is a chloride channel blocker. Picrotoxinin is a noncompetitive GABAA receptor antagonist, which negatively modulates the action of GABA on GABAAA receptors.
  41. GC17256 Pilocarpine HCl

    盐酸毛果芸香碱

    A muscarinic acetylcholine receptor agonist

  42. GC31001 Pilocarpine nitrate

    硝酸毛果芸香碱

    Pilocarpinenitrate是一种选择性的M3型毒蕈碱乙酰胆碱受体(M3muscarinicreceptor)激动剂。
  43. GC11844 Pimavanserin

    匹莫范色林; ACP-103

    A 5-HT2A inverse agonist
  44. GC36919 Pimavanserin tartrate

    匹莫范色林L-酒石酸盐,ACP-103 hemitartrate

    A 5-HT2A inverse agonist
  45. GC30999 Pimethixene (Pimetixene)

    匹美噻吨,Pimetixene

    Pimethixene (Pimetixene) 是抗组胺药和抗血清素能化合物,用作抗偏头痛剂。
  46. GC65296 Pimethixene maleate

    匹美噻吨马来酸盐; Pimetixene maleate

    Pimethixene (Pimetixene) maleate, an antihistamine, anntimigraine agent and antiserotonergic compound, is a highly potent antagonist of a broad range of monoamine receptors, including a variety of serotonin receptors. Pimethixene maleate inhibits 5-HT2A, 5-HT2B, 5-HT2C, 5-HT1A, 5-HT1B, 5-HT6, 5-HT7, Adrenergic α-1A, Dopamine D1 Receptor, Dopamine D2 Receptor, Dopamine D4.4 Receptor, Histamine H1 Receptor, Muscarinic M1 and Muscarinic M2 with pKi of 10.22, 10.44, 8.42, 7.63, < 5, 7.30, 7.28, 7.61, 6.37, 8.19, 7.54, 10.14, 8.61 and 9.38, respectively.
  47. GC10643 Pimozide

    匹莫齐特; R6238

    Pimozide是一种化学结构新颖、高效且口服长效的神经阻滞剂类多巴胺受体抑制剂,对多巴胺D2、D3和D4 受体的Ki值分别为2.4nM、0.2nM和1.8nM。
  48. GC45756 Pimozide-d4

    R6238-d4

    An internal standard for the quantification of pimozide
  49. GC67752 Pimozide-d4-1

    R6238-d4-1

    Pimozide-d4-1 氘代标记的 Pimozide。Pimozide 是 dopamine receptor 的拮抗剂,对 dopamine D2,D3 和 D1 受体的 Ki 值分别为 1.4 nM,2.5 nM 和 588 nM,同时对 α1-adrenoceptor 也有较高亲和性,Ki 值为 39 nM;Pimozide 也是 STAT3 和 STAT5 的抑制剂。
  50. GC18707 Pimprinine

    5-(1H-吲哚基)2-甲基噁唑

    An alkaloid with diverse biological activities
  51. GC17734 Pindolol

    吲哚洛尔; LB-46

    A β1- and β2-AR antagonist

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