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Home >> Signaling Pathways >> Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. 产品名称 Information
  2. GC63134 P11149 P11149 是 Galanthamine 的一个衍生物，是有效的、竞争性的、弱透过血脑屏障的、口服活性的、选择性的 AChE 抑制剂，具有中枢胆碱能活性和安全性。P11149 抑制大鼠 BChE/AChE 的 IC50 值为 1.3 μM。P11149 用于阿尔兹海默症的研究。
  3. GC52342 P4pal10 (trifluoroacetate salt)

    Palmitoyl-SGRRYGHALR-amide, Palmitoyl-SGRRYGHALR-NH2

     A PAR4 and FPR2 antagonist and an FFAR2 agonist
  4. GC44531 PACAP (1-27) (human, mouse, ovine, porcine, rat) (trifluoroacetate salt)

    Pituitary Adenylate Cyclase-activating Peptide (1-27)

     A PACAP receptor agonist
  5. GC44532 PACAP (1-38) (human, mouse, ovine, porcine, rat) (trifluoroacetate salt)

    Pituitary Adenylate Cyclase-activating Peptide (1-38)

     A PACAP receptor agonist
  6. GC44533 PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)

    Pituitary Adenylate Cyclase-activating Peptide (6-27)

     A PACAP receptor antagonist
  7. GC44534 PACAP (6-38) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)

    Pituitary Adenylate Cyclase-activating Peptide (6-38)

     A PACAP receptor antagonist
  8. GN10498 Paeonol

    丹皮酚

     A phenol with diverse biological activities
  9. GC10112 Paliperidone

    9-羟基利培酮; 9-Hydroxyrisperidone

     An atypical antipsychotic
  10. GC61167 Paliperidone palmitate

    棕榈酸帕利哌酮,9-Hydroxyrisperidone palmitate

     Paliperidone Palmitate (9-hydroxyrisperidone palmitate) is a palmitate ester of paliperidone, which is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class.
  11. GC47857 Paliperidone-d4

    帕潘立酮 d4

     An internal standard for the quantification of paliperidone
  12. GC49024 Palmitic Acid MaxSpec® Standard

    棕榈酸

     A long-chain saturated fatty acid
  13. GC49023 Palmitic Acid-d9 MaxSpec® Standard

    棕榈酸-13,13,14,14,15,15,16,16,16-D9

     A quantitative analytical standard guaranteed to meet MaxSpec identity, purity, stability, and concentration specifications
  14. GC47866 Palmitoyl Ethanolamide-d5

    Palmidrold5, PEA15,15,16,16,16d5

     A neuropeptide with diverse biological activities
  15. GC47867 Palmitoylcholine (chloride) An acyl choline
  16. GC36844 Palonosetron

    帕洛诺司琼

     Palonosetron (RS25259, RS 25259 197) is a 5-HT3 antagonist with Ki value of 0.17 nM. It is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).
  17. GC17917 Palonosetron HCl

    盐酸帕洛诺司琼

     A 5-HT3 receptor antagonist
  18. GC49184 Palonosetron N-oxide

    帕洛诺司琼N氧化物

     A metabolite of palonosetron
  19. GC45879 Palonosetron-d3 (hydrochloride)

    盐酸帕洛诺司琼 d3 (盐酸盐)

     A neuropeptide with diverse biological activities
  20. GC32640 Pamicogrel (KBT3022)

    帕米格雷; KBT3022

     A COX inhibitor and an antiplatelet agent
  21. GC44553 Pamoic Acid

    帕莫酸

     A potent agonist of GPR35 orphan receptors
  22. GC70266 Panadiplon Panadiplon（FG 10571；PNU 78875）是一种苯二氮卓类受体，是5GABAA部分激动剂。
  23. GC31022 Pancopride (LAS 30451)

    泮考必利,LAS 30451

     Pancopride (LAS 30451) 是一种新型的强效选择性 5-HT3 受体拮抗剂。
  24. GC47869 Pancuronium (bromide hydrate)

    NSC 293162

     An antagonist of muscle-type nAChRs
  25. GC11773 Pancuronium dibromide

    泮库溴铵

     Pancuronium dibromide 是一种双季铵盐类固醇，是一种神经肌肉松弛剂。
  26. GC12800 PAOPA dopamine D2 receptor modulator
  27. GC44556 PAQ

    3-Phenyl-6-aminoquinoxaline

     A neuroprotective agent
  28. GC40159 PAR1 (1-6) (mouse, rat) (trifluoroacetate salt)

    H-Ser-Phe-Phe-Leu-Arg-Asn, PAR1-AP, Proteinase-Activated Receptor 1, SFFLRN, TRAP, Thrombin Receptor Activating Peptide

     A peptide agonist of PAR1
  29. GC49422 PAR2 (1-6) amide (human) (trifluoroacetate salt)

    SLIGKV-NH2

     A peptide agonist of PAR2
  30. GC14849 Paradol

    姜酮酚; [6]-Gingerone; [6]-Paradol

     A phenolic ketone with diverse biological activities
  31. GP10069 Parathyroid hormone (1-34) (human)

    Teriparatide Acetate; 醋酸特立帕肽; Human parathyroid hormone-(1-34); hPTH (1-34)

     Parathyroid hormone (1-34) (human)是人类甲状旁腺激素（PTH）的N端片段（34个氨基酸），是甲状旁腺激素1（PTH1）受体的激动剂。
  32. GP10106 Parathyroid Hormone (1-34), bovine

    牛甲状旁腺激活素-(1-34),H2N-Ala-Val-Ser-Glu-Ile-Gln-Phe-Met-His-Asn-Leu-Gly-Lys-His-Leu-Ser-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH

    甲状旁腺激素 (1-34), bovine 是一种有效的甲状旁腺激素 (PTH) 受体激动剂。
  33. GP10014 parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis]

    H2N-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH

    Enhancer of blood calcium level
  34. GC47923 Paraxanthine-d6

    1,7-Dimethylxanthine-d6

     An internal standard for the quantification of paraxanthine
  35. GC31069 Pardoprunox (SLV-308)

    SLV-308; DU-126891

     Pardoprunox hydrochloride (DU-126891, SME-308) is a potent but partial dopamine D2 receptor agonist with pEC50 of 8.0, and a partial agonist in the induction of [35S]GTPγS binding with pEC50 of 9.2 and a serotonin 5-HT1A receptor agonist, with pEC50 of 6.3, respectively.
  36. GC30980 Pardoprunox hydrochloride (SLV-308 hydrochloride)

    盐酸帕多芦诺,SLV-308 hydrochloride; DU-126891 hydrochloride

     A dopamine D2 and D3 receptor partial agonist and 5-HT1A agonist
  37. GC36852 Parecoxib

    帕瑞昔布; SC 69124

     A prodrug form of valdecoxib
  38. GC17051 Parecoxib Sodium

    帕瑞昔布钠; SC 69124A

     A prodrug form of valdecoxib
  39. GC36853 Pargyline

    优降宁

     An irreversible MAO inhibitor
  40. GC16824 Pargyline (hydrochloride)

    优降宁盐酸盐；盐酸帕吉林；巴吉林盐酸盐

     An irreversible MAO inhibitor
  41. GC17229 Paroxetine HCl

    盐酸帕罗西汀; BRL29060 hydrochloride; BRL29060A

     A selective serotonin reuptake inhibitor
  42. GC30992 Paroxetine hydrochloride hemihydrate (BRL29060 hydrochloride hemihydrate)

    盐酸帕罗西汀半水合物; BRL29060 hydrochloride hemihydrate; BRL29060A hemihydrate

     Paroxetine HCl (BRL-29060A, FG-7051) is an antidepressant drug of the SSRI type.
  43. GC18102 Paroxetine maleate

    马来酸帕罗西汀

     5-HT uptake inhibitor
  44. GC25708 Paroxetine mesylate

    BRL-29060A mesylate,FG-7051 mesylate

     Paroxetine Mesylate(BRL-29060A mesylate,FG-7051 mesylate) is the mesylate salt form of paroxetine, a phenylpiperidine derivative and a selective serotonin reuptake inhibitor (SSRI) with antidepressant and anxiolytic properties.
  45. GC49624 Paroxetine-d6 (hydrochloride) An internal standard for the quantification of paroxetine
  46. GC30112 PAT-1251

    PAT-1251; GB2064

     PAT-1251是一种有效的，选择性的，可口服的赖氨酰氧化酶样蛋白2(LOXL2)抑制剂，对hLOXL2和hLOXL3的IC50值分别为0.71和1.17μM，同时对小鼠、大鼠和狗LOXL2的抑制作用很强，IC50值分别为0.10，0.12和0.16μM；PAT-1251已经进入临床开发，有治疗多种纤维性疾病的潜力。
  47. GC31949 PAT-1251 Hydrochloride PAT-1251Hydrochloride是一种口服有效的选择性赖氨酰氧化酶样蛋白2(LOXL2)抑制剂，对hLOXL2和hLOXL3的IC50值分别为0.71和1.17μM，同时对小鼠、大鼠和狗LOXL2的抑制作用很强，IC50值分别为0.10，0.12和0.16μM。
  48. GC30861 Pavinetant (MLE-4901)

    MLE-4901; AZD2624; AZD4901

     An NK3 receptor antagonist
  49. GC39419 PBD-150 A glutaminyl cyclase inhibitor
  50. GC72925 PCS1055 PCS1055是毒蕈碱M4受体的选择性和竞争性拮抗剂，IC50为18.1 nM，Kd为5.72 nM。
  51. GC17876 PD 102807 PD 102807 是一种 M4 毒蕈碱受体拮抗剂，IC50 为 90.7 nM。

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