Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC71604 Ondansetron-d3 hydrochloride Ondansetron-d3 hydrochloride是氘标记的盐酸昂丹司琼。
GC71603 Ondansetron-d5 Ondansetron-d5是氘标记的昂丹司琼。
GC19271 ONO-8590580 A negative allosteric modulator of α₅ subunit-containing GABA_A receptors
GC61889 OPC-14523 hydrochloride

OPC-14523盐酸盐
OPC-14523 hydrochloride 是一种具有口服活性的 sigma 和 5-HT1A 受体激动剂，对 sigma 受体 (σ1/2 IC50=47/56 nM)、5-HT1A 受体 (IC50=2.3 nM) 和 5-HT 转运体 (IC50=80 nM) 具有高度亲和力。OPC-14523 hydrochloride 显示抗抑郁药样活性。
GC46010 Opipramol

奥匹哌醇; Ensidon; G-33040
A σ receptor ligand
GC52453 Orexin A (17-33) (human, mouse, rat, bovine) (trifluoroacetate salt)

OXA (17-33)
A peptide orexin receptor 1 agonist
GC52507 Orexin A amide (bovine, human, mouse, rat) (trifluoroacetate salt)

Hypocretin 1, OXA
A hypothalamic neuropeptide
GC44512 Orexin B (human) (trifluoroacetate salt) Orexin B is a hypothalamic neuropeptide that regulates feeding behavior, wakefulness, and behavior under situations of high motivational relevance.
GC49553 Orexin B amide (human) (trifluoroacetate salt)

Hypocretin 2, OXB
A hypothalamic neuropeptide
GC49558 Orexin B amide (mouse, rat) (trifluoroacetate salt)

Hypocretin 2, OXB, RPGPPGLQGRLQRLLQANGNHAAGILTM-NH2
A hypothalamic neuropeptide
GC33510 Org-10490 Org-10490是一种dopamineD1受体和dopamineD2受体的拮抗剂，常用于治疗神经疾病。
GC38828 Org-12962

1-[6-氯-5-(三氟甲基)吡啶-2-基]哌嗪
A 5-HT_2C receptor agonist
GC30852 Org-26576 Org26576是AMPA受体的正变构调节剂。
GC13779 Orphenadrine Citrate

枸酸芬那君
Orphenadrine citrate 是一种具有口服活性且非竞争性的 NMDA 受体拮抗剂（穿过血脑屏障），Ki 为 6.0 μM。
GC33701 Orphenadrine hydrochloride

盐酸奥芬那君；盐酸邻甲苯海拉明；奥芬那君盐酸盐
A muscarinic acetylcholine receptor antagonist
GC40921 Orsellinic Acid

苔色酸
A fungal metabolite with antioxidant and neuroprotective activities
GC63131 Orvepitant maleate

GW823296 maleate
Orvepitant maleate (GW823296 maleate) 是一种有效，选择性，口服活性且耐受性良好的 neurokinin-1 (NK-1) 受体拮抗剂，对人 neurokinin-1 受体的 pKi 为 10.2。Orvepitant maleate 可以穿越血脑屏障。Orvepitant maleate 可用于抑郁症和慢性顽固性咳嗽的研究。
GC69634 OS-3-106 OS-3-106 是一种有效的、透过血脑屏障和选择性的多巴胺 D3 受体 (D3R) 激动剂。OS-3-106 在 D3R 处具有高亲和力 (Ki = 0.2 nM)。OS-3-106 可用于精神兴奋剂成瘾的研究。
GC38829 Osanetant

奥沙奈坦,SR142801
An NK₃ receptor antagonist
GC48405 Osanetant (hydrate)

SR 142801
An NK₃ receptor antagonist
GC61162 Osthenol

7-羟基-8-(3-甲基-2-丁烯)-二氢苯并吡喃,Ostenol
Osthenol(Ostenol)是从独活干根中分离得到的一种前酰化香豆素，是一种可逆的，选择性的竞争性人单胺氧化酶-A(hMAO-A)抑制剂(Ki=0.26µM)。Osthenol对重组hMAO-A具有潜在的选择性抑制作用，IC50为0.74µM，对hMAO-A和hMAO-B表现出较高的选择性指数。
GN10333 Osthole

蛇床子素; Osthol; NSC 31868
A coumarin with diverse biological activities
GC17238 OSU 6162 hydrochloride Dopamine stabilizer
GC10863 Otilonium Bromide

奥替溴铵; Octylonium bromide; SP63
An L- and T-type calcium channel inhibitor and mAChR antagonist
GC47847 Oxamyl

杀线威
A carbamate pesticide
GC12114 Oxaprozin

奥沙普秦; Oxaprozinum; Wy21743
An NSAID and COX inhibitor
GC36828 Oxaprozin D4

Wy-21743 D4
Oxaprozin D4是Oxaprozin的氘代化合物标准品。
GC69640 Oxaprozin-d4

奥沙普秦D4; Wy-21743-d₄
Oxaprozin-d4 是 Oxaprozin 的氘代物。
GC49054 Oxaprozin-d5

Oxaprozinum-d5; Wy21743-d5
An internal standard for the quantification of oxaprozin
GC61401 Oxatomide

欧诗美锭
Oxatomide是一种有效的具有口服活性的双重H1组胺受体(H1-histaminereceptor)和P2X7受体拮抗剂，具有抗组胺和抗过敏活性。Oxatomide几乎完全阻断人P2X7受体中ATP诱导的电流(IC50为0.95μM)。Oxatomide可抑制ATP诱导的Ca2+内流，IC50值为0.43μM，并且还抑制5-羟色胺(serotonin)。
GC46195 Oxcarbazepine-d4

奥卡西平-D4,GP 47680-D4
An internal standard for the quantification of oxcarbazepine
GC30871 Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride)

6-羟基多巴胺盐酸盐; 6-Hydroxydopamine hydrochloride; 6-OHDA hydrochloride
Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride)（6-OHDA）是神经递质多巴胺的拮抗剂。
GC11963 Oxiracetam

奥拉西坦,ISF2522
An Analytical Reference Standard
GC32049 Oxitropium Bromide

氧托溴铵

Oxitropiumbromide是毒蕈碱受体拮抗剂。它是一种用于治疗哮喘和慢性阻塞性肺疾病的抗胆碱能支气管扩张剂药物。
GC12238 Oxomemazine

双氧异丁嗪
Oxomemazine 是一种基于吩噻嗪的组胺 H1 受体阻滞剂，具有明显的抗毒蕈碱特性。
GC16463 Oxotremorine M

碘化氧化震颤素M
A muscarinic receptor agonist and KCNQ2/3 potassium channel blocker
GC38658 Oxotremorine M iodide
Oxotremorine M iodide 是一种有效的，选择性毒蕈碱型乙酰胆碱受体 (mAChR) 激动剂。Oxotremorine M iodide 通过毒蕈碱受体依赖和独立机制增强 NMDA 受体。
GC16156 Oxotremorine sesquifumarate

1-(4-[1-吡咯烷基]-2-丁炔基)-2-吡咯烷酮
A muscarinic acetylcholine receptor agonist
GC48847 Oxprenolol-d7

dl-Alprenolol-d7, dl-Oxprenolol-d7
An internal standard for the quantification of oxprenolol
GC14113 Oxybutynin

奥昔布宁
An antagonist of muscarinic acetylcholine receptors
GC14703 Oxybutynin chloride

盐酸奥昔布宁
An antagonist of muscarinic acetylcholine receptors
GC47850 Oxybutynin-d10 (hydrochloride) An internal standard for the quantification of oxybutynin
GC44525 Oxyntomodulin (human, mouse, rat) (trifluoroacetate salt)

Glicentin (33-69), Proglucagon (33-69)
A peptide hormone
GC40651 Oxyphenbutazone

羟布宗
An NSAID
GC18332 Oxyphenonium (bromide)

奥芬溴铵
A muscarinic acetylcholine receptor antagonist
GC91296 p-Carboxyphenyl Sulfate

Benzoic Acid-4-sulfate, 4-Carboxyphenyl Sulfate, para-Carboxyphenyl Sulfate, 4-Hydroxybenzoic Acid Sulfate, p-Hydroxybenzoic Acid Sulfate, para-Hydroxybenzoic Acid Sulfate

一种硫酸化的酚酸。
GC31282 p-Hydroxybenzaldehyde

对羟基苯甲醛
p-Hydroxybenzaldehyde (4-Hydroxybenzaldehyde, 4-Formylphenol, p-Formylphenol), which can be found in the orchids Gastrodia elata, Galeola faberi and vanilla, is a hydroxybenzaldehyde that reacts with NAD+ and H2O to produce 4-hydroxybenzoate, NADH, and 2 protons. p-Hydroxybenzaldehyde at 101.7 μM can significantly reduce the GABA-induced chloride current of GABAA receptors(α1β2γ2S subtype) expressed.
GC72723 p-Hydroxybenzaldehyde-d4 p-Hydroxybenzaldehyde-d4是氘标记的对羟基苯甲醛。
GC91070 p-methyl-N-salicyloyl Tryptamine

LZWL02003, para-methyl-N-salicyloyl Tryptamine

一种神经保护剂
GC60293 p-MPPI hydrochloride p-MPPI hydrochloride 是一种选择性的，具有高亲和力的 5-HT1A 受体拮抗剂。p-MPPI hydrochloride 能穿过血脑屏障，具有明显的抗抑郁和抗焦虑作用。