BACE-IN-1

目录号: GC31260纯度: >98%
BACE-IN-1(化合物13)是咪唑[1,2-a]吡啶衍的生物,其可以抑制β位点淀粉样蛋白前体蛋白切割酶(BACE),并且其可用于治疗涉及BACE的疾病,例如阿尔茨海默氏病。

BACE-IN-1
Cas No.: 1254166-60-3
规格价格库存数量操作
1mg¥3,570.00现货
1
5mg¥7,140.00现货
1
10mg¥12,138.00现货
1
20mg¥21,420.00现货
1

文献被引

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    183(7):1867-1883 (2020)
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产品描述 Description

BACE-IN-1 (Compound 13) is a substituted lmidazo[1 ,2-a]pyridine derivative which can inhibit β-site amyloid precursor protein-cleaving enzyme (BACE) and that may be useful in the treatment of diseases in which BACE is involved, such as Alzheimer's disease.

[1]. Adnan M.M. Mjalli, et al. SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE AS β-SECRETASE INHIBITORS. WO 2010126745 A1

产品文档 Product Documents

化学性质Chemical Properties

CAS 号
1254166-60-3
SMILES
O=C(C1=CN2C=C(Cl)C=CC2=N1)NC3=NC4=CC=C(OCC5=CC=CC=C5)C=C4N3
分子式
C22H16ClN5O2
分子量
417.85 g/mol
溶解性
Soluble in DMSO
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol