Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC13793 NH125 An antibacterial imidazole
GC44399 NIAD-4 A fluorescent probe for Aβ
GC30870 Nialamide

烟肼酰胺

Nialamide是一种非选择性的,不可逆的单胺氧化酶抑制剂(MAOI),用作抗抑郁药。
GC61467 Niaprazine

尼普拉嗪
Niaprazine是一种具有强效镇静作用的组胺H1受体(histamineH1-receptor)拮抗剂。Niaprazine具有抗组胺和抗血清素活性，并可用于睡眠障碍的研究。
GC52214 Nicotinamide riboside-d4 (triflate) An internal standard for the quantification of nicotinamide riboside
GC16564 Niflumic acid

氟尼酸
A selective COX-2 inhibitor
GC49090 Nilvadipine-d4

(±)-Nilvadipine-d4
An internal standard for the quantification of nilvadipine
GC46185 Nimbin

宁宾
A limonoid with diverse biological activities
GC18084 Nimesulide

尼美舒利; R805
An NSAID and COX2 inhibitor
GC39583 Nimesulide D5

尼美舒利 D5
An internal standard for the quantification of nimesulide
GC47775 Nimodipine-d7

尼莫地平 d7
An internal standard for the quantification of nimodipine
GC31455 Niperotidine

尼匹鲁替定；尼培替丁
Niperotidine是一种组胺H2受体(histamineH2-receptor)拮抗剂。
GC49501 Nirvanol

5-乙基-5-苯基海因
An active metabolite of mephenytoin
GC17627 Nitenpyram

烯啶虫胺
An insecticide
GP10011 Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell

Ac-Pro-Tyr-Asn-Ser-Ser-Pro-Arg-Pro-Glu-Gln-His-Lys-Ser-Tyr-Lys-Cys-OH
一氧化氮生产阻滞剂
GC36747 Nitroaspirin

2-乙酰氧基苯甲酸-3-硝酸甲基苯酯,NCX 4016
Nitroaspirin (NCX 4016) 是一氧化氮 (NO) 供体和阿司匹林的硝基衍生物，Aspirin 与 Nitroaspirin 联合以抑制环加氧酶。Nitroaspirin (NCX 4016) 具有抗血栓形成和抗血小板特性，并作为 COX-1 的直接和不可逆抑制剂。Nitroaspirin (NCX 4016) 通过下调 EGFR/PI3K/STAT3 信号传导和调节 Bcl-2 家族蛋白，在顺铂耐药人卵巢癌细胞中引起细胞周期停滞和凋亡。
GC10525 Nitrocaramiphen hydrochloride M1 muscarinic antagonist
GC34028 Nitroflurbiprofen (HCT 1206)

硝基氟比洛芬; HCT 1206; NO-flurbiprofen; Nitroxybutyl flurbiprofen
Nitroflurbiprofen (HCT 1206) 是一种环氧合酶 (COX) 抑制剂，具有提供一氧化氮 (NO) 的特性，可调节门脉高压性肝硬化大鼠肝内血管张力的增加。
GC31029 Nitroxazepine (CIBA 2330Go)

CIBA 2330Go
Nitroxazepine (CIBA 2330Go) 是一种用于抑郁症研究的三环类抗抑郁药 (TCA)。
GC12794 Nizatidine

尼扎替丁
A histamine H₂ receptor antagonist
GC30347 NK-1 Antagonist 1

罗拉吡坦中间体,NK-1 Antagonist 1
NK-1 Antagonist 1 (NK-1 Antagonist 1) 是一种 NK-1 受体拮抗剂，用于研究 NK-1 相关疾病和病症，如咳嗽、膀胱过度活动症、酒精依赖和抑郁症。
GC69568 NK1 receptor antagonist 2 NK1 receptor antagonist 2 是一种 NK1 受体拮抗剂。NK1 receptor antagonist 2 可用于耳鸣和听力损失的研究。
GC36749 NKP608

(2R,4S)-N-[1-[3,5-双(三氟甲基)苯甲酰]-2-(4-氯苄基)哌啶-4-基]喹啉-4-甲酰胺
NKP608为非肽类4-氨基哌啶衍生物，是神经激肽-1（NK-1）受体拮抗剂，IC50为2.6 nM。
GC63111 NLX-204 hydrochloride NLX-204 is a potent, selective agonist of ERK1/2 phosphorylation-preferring serotonin 5 HT1A receptor with pKi of 10.19.
GC17456 NMDA (N-Methyl-D-aspartic acid)

N-甲基-D-天冬氨酸; N-Methyl-D-aspartic acid
An excitatory neurotransmitter
GC34352 NMDAR antagonist 1

2,2,2-三氟-N-(丙-2-炔-1-基)乙酰胺
NMDAR antagonist 1 is a potent and orally bioavailable NR2B-selective antagonist of NMDAR. It has neuroprotective activity.
GC64521 NMDAR/TRPM4-IN-2 free base

N'-[(3-溴苯基)甲基]-N'-乙基乙烷-1,2-二胺
NMDAR/TRPM4-IN-2 free base (化合物 8) 是一种有效的 NMDAR/TRPM4 相互作用界面抑制剂。NMDAR/TRPM4-IN-2 free base 具有神经保护活性。NMDAR/TRPM4-IN-2 free base 可预防 NMDA 诱导的海马神经元细胞死亡和线粒体功能障碍，其 IC50 值为 2.1 μM。NMDAR/TRPM4-IN-2 free base 保护小鼠免受 MCAO 诱导的脑损伤和 NMDA 诱导的视网膜神经节细胞丢失。
GC31111 NMI 8739

DHA-DA, NMI 8739
A conjugate of DHA and dopamine
GC92131 NN1177 (trifluoroacetate salt) NN1177 (trifluoroacetate salt)是胰高血糖素受体（GCGR）和胰高血糖激素样肽1受体（GLP-1R）的双肽激动剂。
GC44431 nNOS Inhibitor I

Neuronal Nitric Oxide Synthase, NOS I, ncNOS
A selective inhibitor of nNOS
GC44439 NO-Indomethacin

NCX 2121
An NSAID-NO donor hybrid with anti-cancer activity
GC47788 Nociceptin (trifluoroacetate salt)

Orphanin FQ
A neuropeptide
GC52382 Nogo-66 (1-40) (human, mouse, rat) (trifluoroacetate salt)

NEP1-40, Nogo-40, Nogo-A Inhibitory Peptide, RIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNS-NH2
A peptide fragment of Nogo-A
GC17636 Noladin ether

2AG ether, Noladin
A potent and selective agonist of the CB₁ receptor and GPR55
GC13573 Nomifensine

诺米芬辛; (±)-Nomifensin
An inhibitor of norepinephrine and dopamine reuptake
GC10270 Noopept

N-(1-(苯基乙酰基)-L-脯氨酰)甘氨酸乙酯,GVS-111;GVS111;GVS 111;SGS-111;SGS 111;SGS111
An Analytical Reference Standard
GC52399 Norephedrine-d5 (hydrochloride) An internal standard for the quantification of norephedrine
GC44451 Norfluoxetine (hydrochloride)

去甲氟西汀,Desmethylfluoxetine
An active metabolite of fluoxetine
GC49355 Norfluoxetine-d5 (hydrochloride)

诺氟西汀-D5
An internal standard for the quantification of norfluoxetine
GC49851 Norquetiapine

11-(1-哌嗪基)二苯并[B,F][1,4]硫氮杂卓
An active metabolite of quetiapine
GC11989 Nortriptyline (hydrochloride)

盐酸去甲替林; Desmethylamitriptyline hydrochloride; Desitriptilina hydrochloride
A tricyclic antidepressant
GN10695 Notoginsenoside R1

三七皂甙R1,Sanchinoside R1; Sanqi glucoside R1
A saponin
GC18935 NPC-15437 (hydrochloride) A selective PKC inhibitor
GC17604 NPEC-caged-(1S,3R)-ACPD group I and II mGlu receptor agonist
GC11554 NPEC-caged-(S)-3,4-DCPG mGlu8a agonist
GC17075 NPEC-caged-dopamine Dopamine receptor agonist
GC10784 NPEC-caged-LY 379268 group II mGlu receptor agonist
GC11563 NPS 2390
Type I metabotropic glutamate receptor antagonist
GC17037 NQTrp

1,4-Naphthoquinon-2-yl-L-tryptophan
An inhibitor of Aβ oligomerization
GC31015 NRA-0160 NRA-0160是一种选择性的dopamineD4receptor拮抗剂，Ki值为0.48nM；同时对dopamineD2receptor，D3receptor，大鼠5-HT2Areceptor和α1adrenoceptor分别具有不同程度的亲和度，Ki值分别为>10000nM，39nM，180nM和237nM。