Signaling Pathways
Signaling Pathways(信号通路)
- Proteases(63)
- Apoptosis(1190)
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- MAPK Signaling(32)
- Tyrosine Kinase(97)
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- Membrane Transporter/Ion Channel(273)
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- Endocrinology and Hormones(168)
- Neuroscience(462)
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- Other Signal Transduction(141)
- Immunology/Inflammation(1111)
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- PROTAC(254)
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- Others(1718)
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- Toxins(90)
Signaling Pathways 相关产品(35130)
- GC16466Rimonabant hydrochlorideCAS: 158681-13-1纯度: >99.00%
A potent and selective CB 1 receptor antagonist
- GC16497SGI-1776 free baseCAS: 1025065-69-3纯度: >99.00%
SGI-1776 free base是一种ATP竞争性的Pim激酶抑制剂,可抑制Pim-1(IC 50 =7nM)、Pim-2(IC 50 =363nM)和Pim-3(IC 50 =69nM)的活性。
- GC16523DipraglurantCAS: 872363-17-2纯度: >99.50%
Dipraglurant (ADX48621) 是一种有效的、选择性的、具有口服活性和脑渗透性的 mGluR5 负变构调节剂 (NAM),IC50 为 21 nM。
- GC16530Batimastat (BB-94)CAS: 130370-60-4纯度: >98.50% / >98.00%
Batimastat (BB-94)是一种有效的广谱基质金属蛋白酶(MMPs)抑制剂,能够抑制MMP-1,MMP-2,MMP-9,MMP-7和MMP-3,IC 50 值分别为3nM,4nM,4nM,6nM和20nM。
- GC16531Bromodomain Inhibitor, (+)-JQ1CAS: 1268524-70-4纯度: >99.50%
A selective inhibitor of BET bromodomains
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC16466 | Rimonabant hydrochloride | 158681-13-1 | >99.00% | |
A potent and selective CB 1 receptor antagonist | ||||
| GC16468 | CYT387 sulfate salt | 1056636-06-6 | >98.00% | |
A potent inhibitor of JAK1 and JAK2 | ||||
| GC16473 | TC 1 | 362512-81-0 | - | |
σ1 receptor ligand | ||||
| GC16474 | 4-HQN | 491-36-1 | >99.50% | |
A heterocyclic building block | ||||
| GC16489 | CP-466722 | 1080622-86-1 | >99.50% | |
An ATM kinase inhibitor | ||||
| GC16490 | Methyldopa | 555-30-6 | - | |
A DOPA decarboxylase inhibitor | ||||
| GC16491 | GSK962040 | 923565-21-3 | - | |
GSK962040 (GSK962040) 是一种小分子选择性胃动素受体激动剂,pEC50 为 7.9。 | ||||
| GC16494 | Tonabersat | 175013-84-0 | >99.50% | |
An anti-migraine agent | ||||
| GC16496 | Ticlopidine | 55142-85-3 | >98.00% | |
A P2Y 12 receptor antagonist with antiplatelet activity | ||||
| GC16497 | SGI-1776 free base | 1025065-69-3 | >99.00% | |
SGI-1776 free base是一种ATP竞争性的Pim激酶抑制剂,可抑制Pim-1(IC 50 =7nM)、Pim-2(IC 50 =363nM)和Pim-3(IC 50 =69nM)的活性。 | ||||
| GC16501 | Cefoperazone | 62893-19-0 | >99.50% | |
A cephalosporin antibiotic | ||||
| GC16508 | Salicylic acid | 69-72-7 | >98.00% | |
An Analytical Reference Standard | ||||
| GC16519 | ENMD-2076 | 934353-76-1 | >98.00% | |
A multi-kinase inhibitor | ||||
| GC16523 | Dipraglurant | 872363-17-2 | >99.50% | |
Dipraglurant (ADX48621) 是一种有效的、选择性的、具有口服活性和脑渗透性的 mGluR5 负变构调节剂 (NAM),IC50 为 21 nM。 | ||||
| GC16526 | Atropine | 51-55-8 | >99.50% / >98.50% / >98.00% | |
A non-selective muscarinic acetylcholine receptor antagonist | ||||
| GC16527 | X-NeuNAc | 160369-85-7 | - | |
A chromogenic substrate for neuraminidase | ||||
| GC16530 | Batimastat (BB-94) | 130370-60-4 | >98.50% / >98.00% | |
Batimastat (BB-94)是一种有效的广谱基质金属蛋白酶(MMPs)抑制剂,能够抑制MMP-1,MMP-2,MMP-9,MMP-7和MMP-3,IC 50 值分别为3nM,4nM,4nM,6nM和20nM。 | ||||
| GC16531 | Bromodomain Inhibitor, (+)-JQ1 | 1268524-70-4 | >99.50% | |
A selective inhibitor of BET bromodomains | ||||
| GC16532 | Flunarizine 2HCl | 30484-77-6 | >99.50% | |
A calcium antagonist | ||||
| GC16543 | TAK-715 | 303162-79-0 | >98.00% | |
TAK-715是一种高效,具有选择性和口服活性的p38 丝裂原活化蛋白激酶(p38 MAPK)抑制剂,对p38α和p38β的IC 50 值分别为7.1nM和200nM。 | ||||
| GC16561 | Gliquidone | 33342-05-1 | >99.00% | |
A second generation sulfonylurea | ||||
| GC16564 | Niflumic acid | 4394-00-7 | >99.50% | |
A selective COX-2 inhibitor | ||||
| GC16567 | CYM 5442 hydrochloride | 1783987-80-3 | >98.50% | |
A selective SIP 1 receptor agonist | ||||
| GC16568 | AZD1080 | 612487-72-6 | >98.00% | |
A potent inhibitor of GSK3α and GSK3β | ||||
