GlpBio

Signaling Pathways

Signaling Pathways(信号通路)

研究方向

Signaling Pathways 相关产品(35130)

  • GC10479 structure
    GC10479PHA-680632
    CAS: 398493-79-3
    纯度: >99.50%

    An Aurora kinase inhibitor

  • GC10493 structure
    GC10493GDC-0449 (Vismodegib)
    CAS: 879085-55-9
    纯度: >98.00%

    GDC-0449 (Vismodegib)是一种具有口服活性和高效选择性的Smoothened（SMO）受体抑制剂，可抑制Hedgehog信号通路，IC 50 值为3.0nM。同时，也可抑制P-gp和ABCG2的活性，IC 50 值分别为3.0μM和1.4μM。

  • GC10494 structure
    GC10494ADX-47273
    CAS: 851881-60-2
    纯度: >99.00%

    A positive allosteric modulator of mGluR5

  • GC10500 structure
    GC10500Oxcarbazepine
    CAS: 28721-07-5
    纯度: >98.50%

    A prodrug form of 10,11-dihydro-10-hydroxy carbamazepine

  • GC10508 structure
    GC10508Solifenacin hydrochloride
    CAS: 180468-39-7
    纯度: >99.00%

    Solifenacin hydrochloride (YM905 hydrochloride) 是一种毒蕈碱受体拮抗剂，对 M1、M2 和 M3 受体的 pKis 分别为 7.6、6.9 和 8.0。

  • GC10510 structure
    GC10510LDN 57444
    CAS: 668467-91-2

    LDN 57444是一种小分子抑制剂，可阻断UCHL1的去泛素化酶活性（K i =0.40μM；IC 50 =0.88μM），抑制UCHL3的IC 50 值为25μM。

  • GC10511 structure
    GC10511Olopatadine HCl
    CAS: 140462-76-6
    纯度: >99.50%

    A histamine H 1 receptor antagonist

  • GC10512 structure
    GC10512Y-27632 dihydrochloride
    CAS: 129830-38-2
    纯度: >98.00%

    Y-27632 dihydrochloride 作为一种选择性 Rho 激酶抑制剂，是一种新型支气管扩张剂。

  • GC10516 structure
    GC10516Rofecoxib
    CAS: 162011-90-7
    纯度: >99.50%

    A COX-2 inhibitor

  • GC10518 structure
    GC10518AICAR
    CAS: 2627-69-2
    纯度: >98.00% / >99.00%

    AICAR（也称为 acadesine）是一种嘌呤核苷。

  • GC10521 structure
    GC10521Podophyllotoxin
    CAS: 518-28-5
    纯度: >99.50%

    A lignan with diverse biological activities

  • GC10522 structure
    GC10522Felbamate
    CAS: 25451-15-4
    纯度: >98.00%

    An inhibitor of NMDA receptors and a modulator of GABA A receptors

  • GC10528 structure
    GC10528Salirasib
    CAS: 162520-00-5
    纯度: >98.00%

    A Ras inhibitor with anti-cancer and anti-atherogenic activity

  • GC10531 structure
    GC10531AGI-5198
    CAS: 1355326-35-0
    纯度: >98.00%

    A potent, selective inhibitor of IDH1 mutations

  • GC10538 structure
    GC10538Pifithrin-α (PFTα)
    CAS: 63208-82-2
    纯度: >98.00%

    Pifithrin-α是一种p53抑制剂。

  • GC10539 structure
    GC10539Marbofloxacin
    CAS: 115550-35-1
    纯度: >99.50% / >98.00%

    A fluoroquinolone antibiotic

  • GC10542 structure
    GC10542CP 80633
    CAS: 135637-46-6

    Inhibitor of phosphodiesterase type 4

  • GC10556 structure
    GC10556PF-670462
    CAS: 950912-80-8
    纯度: >99.50%

    An inhibitor of the CK1 isoforms CK1ε and CK1δ

  • GC10566 structure
    GC10566Meropenem trihydrate
    CAS: 119478-56-7
    纯度: >99.50%

    A carbapenem antibiotic

  • GC10570 structure
    GC10570BMS-538203
    CAS: 543730-41-2

    HIV integrase inhibitor,highly efficient

  • GC10573 structure
    GC10573L803-mts
    CAS: 1043881-55-5

    Selective peptide inhibitor of glycogen synthase kinase-3 (GSK-3)

  • GC10576 structure
    GC10576Imeglimin
    CAS: 775351-65-0

    Imeglimin (EMD 387008) 是一种口服降糖剂。

  • GC10579 structure
    GC10579Ouabain Octahydrate
    CAS: 11018-89-6
    纯度: >99.50%

    Ouabain Octahydrate是一种Na + /K + -ATPase抑制剂，能够用于研究充血性心力衰竭。

  • GC10580 structure
    GC10580AICAR phosphate
    CAS: 681006-28-0
    纯度: >99.00% / >98.00%

    An activator of AMPK