GlpBio

Signaling Pathways

Signaling Pathways(信号通路)

研究方向

Signaling Pathways 相关产品(35130)

  • GC14682 structure
    GC14682PCI-24781 (CRA-024781)
    CAS: 783355-60-2
    纯度: >98.50%

    An HDAC inhibitor

  • GC14683 structure
    GC14683Sunitinib malate
    CAS: 341031-54-7
    纯度: >99.00%

    A multi-kinase inhibitor

  • GC14693 structure
    GC14693CMK
    CAS: 821794-90-5
    纯度: >99.50%

    CMK 是一种 RSK2 激酶抑制剂，与 FMK 相比，具有相似的效力，但化学稳定性较低。

  • GC14695 structure
    GC14695CO-1686 (AVL-301)
    CAS: 1374640-70-6
    纯度: >99.50%

    A selective inhibitor of mutant EGFR

  • GC14703 structure
    GC14703Oxybutynin chloride
    CAS: 1508-65-2
    纯度: >98.00%

    An antagonist of muscarinic acetylcholine receptors

  • GC14704 structure
    GC14704Levonorgestrel
    CAS: 797-63-7
    纯度: >99.00% / >98.00%

    Levonorgestrel是一种口服有效的孕酮抑制剂。

  • GC14709 structure
    GC14709AZD1152
    CAS: 722543-31-9
    纯度: >99.50%

    AZD1152是一种高度选择性的Aurora B激酶（AURKB）抑制剂，IC 50 值为0.37nM。AZD1152是一种前体药物，在体内转化为活性形式AZD1152-hydroxyquinazoline pyrazol anilide（AZD1152-hQPA），主要用于研究与治疗急性髓系白血病等恶性肿瘤。

  • GC14715 structure
    GC14715AZ 12080282 dihydrochloride
    纯度: >98.00%

    刺猬抑制剂

  • GC14720 structure
    GC14720Zalcitabine
    CAS: 7481-89-2
    纯度: >99.50%

    A nucleoside reverse transcriptase inhibitor

  • GC14726 structure
    GC14726Mianserin HCl
    CAS: 21535-47-7
    纯度: >99.50%

    Mianserin HCl是一种四环类化合物，对5-HT6受体的K i 值为0.056 ± 0.012μM。

  • GC14729 structure
    GC14729(R)-Crizotinib
    CAS: 877399-52-5
    纯度: >99.50%

    A c-MET and ALK receptor tyrosine kinase inhibitor

  • GC14732 structure
    GC14732PLX-4720
    CAS: 918505-84-7
    纯度: >99.50%

    An orally-available inhibitor of the B-raf mutant B-Raf V600E

  • GC14733 structure
    GC14733SU14813
    CAS: 627908-92-3
    纯度: >98.50%

    A dual VEGFR and PDGFR family kinase inhibitor

  • GC14743 structure
    GC14743WY 45233 succinate
    CAS: 448904-47-0

    serotonin and noradrenalin reuptake inhibitor

  • GC14745 structure
    GC14745Plerixafor (AMD3100)
    CAS: 110078-46-1
    纯度: >98.00% / >99.00%

    Plerixafor(AMD3100) 是 CXCR4 和 CXCL12 介导的趋化作用的小分子抑制剂，IC50 值分别为 44 nM 和 5.7 nM 。

  • GC14746 structure
    GC14746Meropenem
    CAS: 96036-03-2
    纯度: >98.00%

    美罗培南是一种碳青霉烯类抗菌剂。

  • GC14751 structure
    GC14751Malotilate
    CAS: 59937-28-9
    纯度: >99.50%

    A hepatoprotective agent

  • GC14759 structure
    GC14759Fenoldopam
    CAS: 67227-56-9

    An agonist of dopamine D 1A and D 1B receptors

  • GC14764 structure
    GC14764Lamotrigine
    CAS: 84057-84-1
    纯度: >99.50%

    An anticonvulsant

  • GC14769 structure
    GC14769Carvedilol
    CAS: 72956-09-3
    纯度: >99.50% / >98.00%

    Carvedilol是一种非选择性α1和β-肾上腺素能受体（Ars）的拮抗剂。

  • GC14783 structure
    GC14783Trilostane
    CAS: 13647-35-3
    纯度: >99.50%

    A 3β-hydroxysteroid dehydrogenase inhibitor

  • GC14785 structure
    GC14785Alvelestat
    CAS: 848141-11-7
    纯度: >99.50%

    An inhibitor of neutrophil elastase

  • GC14787 structure
    GC14787Curcumin
    CAS: 458-37-7
    纯度: >98.00%

    A yellow pigment with diverse biological activities

  • GC14788 structure
    GC14788Tianeptine
    CAS: 66981-73-5
    纯度: >98.00%

    An atypical antidepressant