Signaling Pathways(信号通路)

Cat.No. 产品名称 Information

GC91621 WLB-89462 WLB-89462 is a ligand of sigma intracellular receptor 2 (σ2 receptor).

GC91615 AZD 5462 AZD 5462 is an agonist of relaxin family peptide receptor 1 (RXFP1).

GC91613 FerroLOXIN-1 FerroLOXIN-1 is an inhibitor of the 15-lipoxygenase-2 (15-LO-2) and phosphatidylethanolamine-binding protein 1 (PEBP1) catalytic complex.

GC91612 FDW028 FDW028 is an inhibitor of fucosyltransferase 8 (FUC8).

GC91604 8RK64 8RK64 is a covalent inhibitor of ubiquitin C-terminal hydrolase L1 (UCH-L1; IC50 = 0.32 µM) and a click chemistry reagent.

GC91603 Homogentisic Acid lactone

Homogentisic Acid γ-lactone,NSC 61996

Homogentisic acid lactone is a fungal metabolite that has been found in the fungus WF5, has fungicidal activity, and is the lactonized form of homogentisic acid , an intermediate in aromatic amino acid metabolism.

GC91602 PFI-6 PFI-6 is a chemical probe for the YEATS domain-containing proteins MLLT1 and MLLT3 (IC50s = 140 and 160 nM, respectively).

GC91598 GPX4 16

Glutathione Peroxidase 4 16

GPX4 16 is an inhibitor of glutathione peroxidase 4 (GPX4).

GC91595 PDIC-NC PDIC-NC is an activator of stimulator of interferon genes (STING) and an anticancer agent.

GC91594 LYS-006 (hydrochloride) LYS-006 is an inhibitor of leukotriene A4 (LTA4) hydrolase.

GC91592 CP-4 CP-4 is a fluorescent probe for mesenchymal stem cells.

GC91590 DTPD-Q

2,5-Bis(o-tolylamino)cyclohexa-2,5-diene-1,4-dione,DTPD-quinone

DTPD-Q is an oxidized derivative of the antioxidant and methylphenyl substituted p-phenylenediamine DTPD.

GC91586 PROTAC RAF Degrader 1

SJF-0628

PROTAC RAF degrader 1 is a proteolysis-targeting chimera (PROTAC) that contains the inhibitor of mutant V600E and wild-type B-RAF vemurafenib (PLX4032; ) conjugated to VHL ligand 1 .

GC91585 10α-hydroxy Naltrexone 10α-hydroxy Naltrexone is a derivative of the opioid antagonist naltrexone.

GC91584 Pomalidomide 4'-alkylC6-amine (hydrochloride) Pomalidomide 4'-alkylC6-amine is a building block in the synthesis of proteolysis-targeting chimeras (PROTACs) and a derivative of the cereblon inhibitor pomalidomide .

GC91583 Clerosterol

(-)-Clerosterol,NSC 144945,δ5,25-Stigmastadienol

Clerosterol is a phytosterol that has been found in C. fragile and has diverse biological activities.

GC91582 Pomalidomide 4'-PEG5-amine (hydrochloride) Pomalidomide 4’-PEG5-amine is a PEGylated form of the cereblon (CRBN) inhibitor pomalidomide .

GC91581 10-(Phosphonooxy)-1-decanole

10-Hydroxydecyl dihydrogen phosphate,HDP

10-(Phosphonooxy)-1-decanole is a hydrolytic degradation product of 10-methacryloyloxydecyl dihydrogen phosphate-N-methylacryloyl glycine (MDP-NMGly) dental primers.

GC91576 Nedometinib

NFX-179

Nedometinib is a MEK1 inhibitor (IC50 = 135 nM).

GC91574 (±)2-HOTrE

FA 18:3;O,(±)2-9(Z),12(Z),15(Z)-HOTrE,α-Hydroxylinolenic Acid,2-Hydroxylinolenic Acid,(±)-2-hydroxy-9(Z),12(Z),15(Z)-OTrE

(±)2-HOTrE is an oxylipin.

GC91565 GSK199 analog (hydrochloride) GSK199 analog is an inhibitor of peptidyl arginine deiminase 4 (PAD4) and a derivative of the PAD4 inhibitor GSK199.

GC91549 L-742,001 (hydrochloride) L-742,001 is an inhibitor of influenza virus PA endonuclease (IC50 = 0.5 µM), an essential subdomain of the viral RNA polymerase.

GC91548 Rosuvastatin EP Impurity A (calcium salt) Rosuvastatin EP impurity A is a potential impurity in commercial preparations of the HMG-CoA reductase inhibitor rosuvastatin.

GC91547 Tanzawaic Acid B

(+)-Tanzawaic Acid B

Tanzawaic acid B is a fungal metabolite that has been found in Penicillium and has diverse biological activities.

GC91544 Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH

Fmoc-Lys(tBuOCO-(CH2)16-CO-Glu(AEEA-AEEA)-OtBu)-OH

Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH is a building block in the synthesis of the glucagon-like peptide 1 receptor (GLP-1R) agonist semaglutide .

GC91543 (E/Z)-Droloxifene

3-Hydroxytamoxifen

(E/Z)-Droloxifene is a mixture of (E)-droloxifene, a selective estrogen receptor modulator (SERM), and (Z)-droloxifene.

GC91540 5-Acetamide-Butenolide

4-acetamido-4-hydroxy-2-Butenoic Acid γ-lactone,NSC 114350

5-Acetamide-butenolide is a mycotoxin that has been found in Fusarium and has pro-oxidant activity.

GC91533 DTPD

N1,N4-bis(2-Methylphenyl)benzene-1,4-diamine,N,N'-di(o-tolyl)-p-phenylenediamine

DTPD is a substituted p-phenylenediamine and non-oxidized version of DTPD-Q .

GC91530 β-Ionone Acid β-Ionone acid is the acid form of the β-carotenoid derivative β-ionone.

GC91514 para-methoxy-2-amino Benzamidoxime

PMA,p-methoxy-2-amino Benzamidoxime

para-methoxy-2-amino-Benzamidoxime (PMA) is a fluorescent and reactive probe for ketones.

GC91507 CP 93,129 CP 93,129 is an agonist of the serotonin (5-HT) receptor subtype 5-HT1B.

GC91506 Bayer 18 Bayer 18 is a tyrosine kinase 2 (TYK2) inhibitor (IC50 = 18.7 nM).

GC91499 Voriconazole-d3 N-oxide Voriconazole-d3 N-oxide is intended for use as an internal standard for the quantification of voriconazole N-oxide by GC- or LC-MS.

GC91497 EB 47 (hydrochloride) EB 47 is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1; IC50 = 45 nM) and a dual site inhibitor of tankyrase 2 (TNKS2; IC50 = 45 nM).

GC91494 6-Deoxy-8-O-methylrabelomycin

(-)-8-O-Methyltetrangomycin,MM 47755

6-Deoxy-8-O-methylrabelomycin is an anthraquinone that has been found in Pseudonocardia with antiparasitic and antibiotic activities.

GC91493 Semaglutide Side Chain Semaglutide side chain is a synthetic intermediate.

GC91492 Propiverine N-oxide Propiverine N-oxide is an active metabolite of the muscarinic acetylcholine receptor antagonist propiverine .

GC91489 Chondroitin Sulfate A (sodium salt)

Chondroitin-4-sulfate,CSA

Chondroitin sulfate A (CSA) is a glycosaminoglycan.

GC91488 Proxymetacaine (hydrochloride)

Proparacaine

Proxymetacaine is an anesthetic.

GC91483 DPPD-Q

C.I. 56000,2,5-Dianilino-1,4-benzoquinone,2,5-Dianilino-p-benzoquinone,2,5-Dianilino-para-benzoquinone,N,N′-Diphenyl-1,4-phenylenediamine quinone,N,N′-Diphenyl-p-phenylenediamine quinone,N,N′-Diphenyl-para-phenylenediamine quinone,NSC 11

DPPD-Q is an oxidized derivative of the antioxidant and substituted p-phenylenediamine DPPD.